ChemicalBook > CAS DataBase List > 1,10-Phenanthroline hydrate

1,10-Phenanthroline hydrate

Product Name
1,10-Phenanthroline hydrate
CAS No.
5144-89-8
Chemical Name
1,10-Phenanthroline hydrate
Synonyms
1,10-PHENANTHROLINE MONOHYDRATE;ORTHO-PHENANTHROLINE;Phenanthroline Monohydrate;1,10-PHENANTHROLINE H2O;O-PHENANTHROLINE MONOHYDRATE;1,10-Phenanthroline, ACS, 99%;10-Phenanthroline monohydrate;PHENYLANTHROLINE HYDRATE 1,10-;1,10-PHENANTHROLINE AR;Black bone vine extract
CBNumber
CB8290304
Molecular Formula
C12H8N2.H2O
Formula Weight
198.22
MOL File
5144-89-8.mol
More
Less

1,10-Phenanthroline hydrate Property

Melting point:
100-104 °C(lit.)
Density 
1.10
vapor density 
6.2 (vs air)
storage temp. 
Sealed in dry,Room Temperature
solubility 
methanol: soluble200MM (Stock solution is stable for months at –20° C.)
form 
Needle-Like Crystals
color 
Off-white, may become cream-colored during storage
Water Solubility 
<0.01 g/100 mL at 21 ºC
Merck 
14,7214
BRN 
4008096
Stability:
Stable. Incompatible with iron, other heavy metals, strong oxidizing agents, strong acids.
CAS DataBase Reference
5144-89-8(CAS DataBase Reference)
EPA Substance Registry System
1,10-Phenanthroline, monohydrate (5144-89-8)
More
Less

Safety

Hazard Codes 
T,N
Risk Statements 
25-50/53
Safety Statements 
45-60-61
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
RTECS 
SF8437000
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29339990
Toxicity
LD50 orally in Rabbit: 132 mg/kg
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
77500
Product name
1,10-Phenanthroline monohydrate
Purity
for the spectrophotometric determination of Fe, Pd, V, ≥99.0%
Packaging
5G
Price
$61.4
Updated
2024/03/01
Sigma-Aldrich
Product number
77500
Product name
1,10-Phenanthroline monohydrate
Purity
for the spectrophotometric determination of Fe, Pd, V, ≥99.0%
Packaging
25g
Price
$242
Updated
2024/03/01
Sigma-Aldrich
Product number
320056
Product name
1,10-Phenanthroline monohydrate
Purity
ACS reagent, 99%
Packaging
5g
Price
$70.8
Updated
2024/03/01
Sigma-Aldrich
Product number
320056
Product name
1,10-Phenanthroline monohydrate
Purity
ACS reagent, 99%
Packaging
25g
Price
$209
Updated
2024/03/01
Sigma-Aldrich
Product number
1.07225
Product name
1,10-Phenanthroline monohydrate
Purity
GR ACS
Packaging
10g
Price
$242
Updated
2024/03/01
More
Less

1,10-Phenanthroline hydrate Chemical Properties,Usage,Production

Chemical Properties

white crystals or powder

Uses

1,10-Phenanthroline monohydrate is useful to study the DNA-protein interactions due to its nuclease activity. It is used as a redox indicator and reagent for spectrophotometric assay of silver. It acts as a chelating ligand for the determination of Fe, Pd and V. It also acts as a matrix metalloproteinase inhibitor. It is a photometric reagent for iron, which forms a red chelate with ferrous (iron II) ion.

Uses

When complexed with copper, it possesses nuclease activity that has been used to study DNA-protein interactions.
1,10-Phenanthroline monohydrate is an aromatic nitrogen heterocycle that may be used as a chelating agent in the preparation of metal-chelate complexes.

General Description

White crystalline powder or solid. Slight odor.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

1,10-Phenanthroline hydrate is incompatible with strong oxidizers. 1,10-Phenanthroline hydrate is also incompatible with strong acids. 1,10-Phenanthroline hydrate forms complex compounds with ferrous ions. .

Fire Hazard

Flash point data for 1,10-Phenanthroline hydrate are not available. 1,10-Phenanthroline hydrate is probably combustible.

Biochem/physiol Actions

Metalloprotease inhibitor; chelates iron, zinc and other divalent metals. Effective concentration 1-10 mM.

Purification Methods

Crystallise its picrate (m 191o) from EtOH; then the free base is liberated with aqueous alkali, dried at 78o/8mm over P2O5 and crystallised from pet ether (b 80-100o). [Cumper et al. J Chem Soc 1188 1962.] It can be purified by zone melting. It has also been crystallised from hexane, *benzene/pet ether (b 40-60o) or sodium-dried *benzene, dried and stored over H2SO4. The monohydrate is obtained by crystallisation from aqueous EtOH or ethyl acetate. It has been crystallised from H2O (300 parts) to give the monohydrate m 102-103o which sublimes at 10-3mm [Fielding & LeFevre J Chem Soc 1811 1951.] The anhydrous compound has m 118o (after drying at high vacuum at 80o) and is also obtained by recrystallisation from pet ether or *C6H6 (70 parts) and drying at 78o/8mm. [UV: Badger et al. J Chem Soc 3199 1951.] IthasapKainH2Oof 4.857 (25o) or 5.02 (20o) and 4.27 in 50% aqueous EtOH (20o). [Albert et al. J Chem Soc 2240 1948]. [Beilstein 23 H 227, 23 II 235, 23/8 V 419.]

1,10-Phenanthroline hydrate Preparation Products And Raw materials

Raw materials

Preparation Products

1 10-PHENANTHROLINE-5 6-DIONE 97 4-Vinylcyclohexene dioxide
More
Less

1,10-Phenanthroline hydrate Suppliers

Americas 1 Australia 1 Austria 1 Belgium 1 Brazil 1 Canada 2 China 382 Czech Republic 3 Europe 4 France 3 Germany 8 India 28 Japan 8 Mexico 2 Poland 1 Russia 1 South Korea 1 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 24 United States 70 Global 546
SHENYANG SINOCHEM BIOTECH CO.,LTD
Tel
024-23769576 13840269002
Email
274311108@qq.com
Country
China
ProdList
392
Advantage
58
Shenyang yimoke chemical products co. LTD
Tel
13998106873
Email
297303255@qq.com
Country
China
ProdList
144
Advantage
58
Kaiyuan city Shenxin fine chemical co., ltd.
Tel
024-024-22595298 18698863499
Fax
024-22595296
Email
1253960@qq.com
Country
China
ProdList
134
Advantage
58
Shanghai Rolead Chemical Technology Co., Ltd.
Tel
021-69992220 13701886816
Fax
021-69992237
Email
roleadchem@163.com
Country
China
ProdList
4759
Advantage
50
Chongqing Yuzhiquan Biological Technology Co., Ltd.
Tel
18306022109
Fax
QQ:2966918840
Email
3236923470@qq.com
Country
China
ProdList
292
Advantage
58
Shenyang Shengyuan chemical industry co., ltd
Tel
13190211560 13190211560
Email
1319074246@qq.com
Country
China
ProdList
94
Advantage
58
Shenyang Snota Biotech Co.,Ltd
Tel
+86-024-31174117 +86-18002429090
Fax
024-31174117
Email
2193387905@qq.com
Country
China
ProdList
103
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3576
Advantage
66
More
Less

View Lastest Price from 1,10-Phenanthroline hydrate manufacturers

Henan Fengda Chemical Co., Ltd
Product
1,10-Phenanthroline hydrate 5144-89-8
Price
US $8.00-0.80/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-09
Shenyang Simchoice Chemical Co.,Ltd
Product
1,10-Phenanthroline monohydrate 5144-89-8
Price
US $100.00-95.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
6000 per month
Release date
2023-01-03
Shanghai UCHEM Inc.
Product
1,10-phenanthrollne monohydrate 5144-89-8
Price
US $22.00-161.00/g
Min. Order
100g
Purity
0.98
Supply Ability
100kg
Release date
2023-10-18

5144-89-8, 1,10-Phenanthroline hydrateRelated Search:

Bathocuproine p-Toluenesulfonic acid monohydrate o-Phenanthroline Chloral hydrate 1,7-PHENANTHROLINE Levofloxacin heMihydrate Citric acid monohydrate MELIBIOSE 5,6-Dimethyl-1,10-phenanthroline 5-CHLORO-1,10-PHENANTHROLINE Neocuproine 5-NITRO-1 10-PHENANTHROLINE HYDRATE & o-Phenanthroline monohydrochloride monohydrate 3,4,7,8-Tetramethyl-1,10-phenanthroline 4,7-Dimethyl-1,10-phenanthroline BATHOPHENANTHROLINEDISULFONIC ACID DISODIUM SALT TRIHYDRATE Bathophenanthroline BATHOCUPROINEDISULFONIC ACID DISODIUM SALT Phenanthroline Monohydrate

  • 1,10-PHENANTHROLINE H2O
  • 1,10-Phenanthroline monohydrate, reagent ACS
  • 1,10-Phenanthrolinemonhydrate
  • 1,10-Phenanthroline monohydrate, ACS
  • 1,10-Phenanthroline, ACS, 99%
  • 1,10-PHENANTHROLINE MONOHYDRATE extrapure AR
  • 1,10-Phenanthroline, Monohydrate, Reagent
  • 1,10-Phenanthroline Monohydrate [for Biochemical Research]
  • 1,10-PHENANTHROLINE AR
  • 1,10-PHENANTHROLINE AR (H2O)
  • 1,10-phenanthrolinemonorate
  • 1,10-Phenanthroline hydrate,99+%
  • 1,10-Phenanthroline Monohydrate,98%
  • o-Phenanthroline monohydrate, redox indicator, reagent grade, ACS
  • 1,10-Phenanthroline monohydrate p.a.
  • o-Phenanthroline Monohydrate, GR ACS
  • 1,10-Phenanthroline&nbsp
  • 1,10-Phenanthroline Monohydrate, 99+% 25GR
  • 1,10-Phenanthroline Monohydrate, 99+% 5GR
  • glaucescent fissistigma root P.E.
  • 1,10-Phenanthroline monohydrate≥ 99.5% (Titration)
  • O-phenanthroline indicator solution
  • 10-Phenanthroline monohydrate
  • 1,10- phenanthroline ferrous indicator
  • 1,10-Phenanthroline hydrate solution
  • 1,10-Phenanthroline monohydrate, 99%, indicator, ACS reagent
  • o-Phenanthroline - CAS 5144-89-8 - Calbiochem
  • 1,10-PHENANTHROLINE MONOHYDRATE, REAGENT (ACS)1,10-PHENANTHROLINE MONOHYDRATE, REAGENT (ACS)1,10-PHENANTHROLINE MONOHYDRATE, REAGENT (ACS)1,10-PHENANTHROLINE MONOHYDRATE, REAGENT (ACS)
  • 1,10-PHENANTHROLINE SOLUTION, 0.12% in Water1,10-PHENANTHROLINE SOLUTION, 0.12% in Water1,10-PHENANTHROLINE SOLUTION, 0.12% in Water
  • 1,10-PHENANTHROLINE 1HYD
  • 1,10-Phenathroline(Monohydrate)
  • 1,10-PHENANTHROLINE HYDRATE
  • 1,10-PHENANTHROLINE MONOHYDRATE
  • 1,10-PHENANTHROLINE MONOHYDRATE (O-)
  • ORTHO-PHENANTHROLINE
  • ORTHOPHENANTHROLINE MONOHYDRATE
  • O-PHENANTHROLINE MONOHYDRATE
  • O-PHENANTHROLINE HYDRATE
  • PHENYLANTHROLINE HYDRATE 1,10-
  • 1,10-phenanthrollne,monohydrate
  • 4,5-Phenanthrolinemonohydrate
  • 1 10-PHENANTHROLINE MONOHYDRATE 99% &
  • 1,10-PHENANTHROLINE MONOHYDRATE*ACS REAG ENT
  • 1,10-PHENANTHROLINE MONOHYDRATE, 99%, A. C.S. REAGENT
  • 1,10-Phenanthroline(Monohydrate)Gr
  • 1,10-PhenanthrolineGrMonohydrate-RedoxIndicator
  • 1,10-PhenanthrolineGrMonohydrate
  • 1,10-PHENANTHROLINE MONOHYDRATE, 99+%
  • Phenanthroline Monohydrate
  • Black bone vine extract
  • HISTOLOGICAL FIXATIVE A.F.A. HISTONORM
  • 1,10-Phenanthroline monohydrate ACS reagent, puriss. p.a., >=99.5% (calc. to the dried substance), for redox titration
  • 1,10-Phenanthroline monohydrate Vetec(TM) reagent grade
  • 1,10-PHENANTHROLINE 1H2O
  • Phenanthroline analytical grade
  • EGG YOLK (6X100ML)+TELLUR.(6X) Y-IRR.
  • 1,10-PhenanthrolineMonohydrate[forBiochemicalResearch]&gt
  • 1,10-Phenanthroline monohydrate, 98%, for analysis