ChemicalBook > CAS DataBase List > 1,10-Phenanthroline hydrate

1,10-Phenanthroline hydrate

Product Name
1,10-Phenanthroline hydrate
CAS No.
5144-89-8
Chemical Name
1,10-Phenanthroline hydrate
Synonyms
1,10-PHENANTHROLINE MONOHYDRATE;ORTHO-PHENANTHROLINE;Phenanthroline Monohydrate;1,10-PHENANTHROLINE H2O;O-PHENANTHROLINE MONOHYDRATE;1,10-Phenanthroline, ACS, 99%;10-Phenanthroline monohydrate;PHENYLANTHROLINE HYDRATE 1,10-;1,10-PHENANTHROLINE AR;Black bone vine extract
CBNumber
CB8290304
Molecular Formula
C12H8N2.H2O
Formula Weight
198.22
MOL File
5144-89-8.mol
More
Less

1,10-Phenanthroline hydrate Property

Melting point:
100-104 °C(lit.)
Density 
1.10
vapor density 
6.2 (vs air)
storage temp. 
Sealed in dry,Room Temperature
solubility 
methanol: soluble200MM (Stock solution is stable for months at –20° C.)
form 
Needle-Like Crystals
color 
Off-white, may become cream-colored during storage
Water Solubility 
<0.01 g/100 mL at 21 ºC
Merck 
14,7214
BRN 
4008096
Stability:
Stable. Incompatible with iron, other heavy metals, strong oxidizing agents, strong acids.
CAS DataBase Reference
5144-89-8(CAS DataBase Reference)
EPA Substance Registry System
1,10-Phenanthroline, monohydrate (5144-89-8)
More
Less

Safety

Hazard Codes 
T,N
Risk Statements 
25-50/53
Safety Statements 
45-60-61
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
RTECS 
SF8437000
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29339990
Toxicity
LD50 orally in Rabbit: 132 mg/kg
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
77500
Product name
1,10-Phenanthroline monohydrate
Purity
for the spectrophotometric determination of Fe, Pd, V, ≥99.0%
Packaging
5G
Price
$61.4
Updated
2024/03/01
Sigma-Aldrich
Product number
77500
Product name
1,10-Phenanthroline monohydrate
Purity
for the spectrophotometric determination of Fe, Pd, V, ≥99.0%
Packaging
25g
Price
$242
Updated
2024/03/01
Sigma-Aldrich
Product number
320056
Product name
1,10-Phenanthroline monohydrate
Purity
ACS reagent, 99%
Packaging
5g
Price
$70.8
Updated
2024/03/01
Sigma-Aldrich
Product number
320056
Product name
1,10-Phenanthroline monohydrate
Purity
ACS reagent, 99%
Packaging
25g
Price
$209
Updated
2024/03/01
Sigma-Aldrich
Product number
1.07225
Product name
1,10-Phenanthroline monohydrate
Purity
GR ACS
Packaging
10g
Price
$242
Updated
2024/03/01
More
Less

1,10-Phenanthroline hydrate Chemical Properties,Usage,Production

Chemical Properties

white crystals or powder

Uses

1,10-Phenanthroline monohydrate is useful to study the DNA-protein interactions due to its nuclease activity. It is used as a redox indicator and reagent for spectrophotometric assay of silver. It acts as a chelating ligand for the determination of Fe, Pd and V. It also acts as a matrix metalloproteinase inhibitor. It is a photometric reagent for iron, which forms a red chelate with ferrous (iron II) ion.

Uses

When complexed with copper, it possesses nuclease activity that has been used to study DNA-protein interactions.
1,10-Phenanthroline monohydrate is an aromatic nitrogen heterocycle that may be used as a chelating agent in the preparation of metal-chelate complexes.

General Description

White crystalline powder or solid. Slight odor.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

1,10-Phenanthroline hydrate is incompatible with strong oxidizers. 1,10-Phenanthroline hydrate is also incompatible with strong acids. 1,10-Phenanthroline hydrate forms complex compounds with ferrous ions. .

Fire Hazard

Flash point data for 1,10-Phenanthroline hydrate are not available. 1,10-Phenanthroline hydrate is probably combustible.

Biochem/physiol Actions

Metalloprotease inhibitor; chelates iron, zinc and other divalent metals. Effective concentration 1-10 mM.

Purification Methods

Crystallise its picrate (m 191o) from EtOH; then the free base is liberated with aqueous alkali, dried at 78o/8mm over P2O5 and crystallised from pet ether (b 80-100o). [Cumper et al. J Chem Soc 1188 1962.] It can be purified by zone melting. It has also been crystallised from hexane, *benzene/pet ether (b 40-60o) or sodium-dried *benzene, dried and stored over H2SO4. The monohydrate is obtained by crystallisation from aqueous EtOH or ethyl acetate. It has been crystallised from H2O (300 parts) to give the monohydrate m 102-103o which sublimes at 10-3mm [Fielding & LeFevre J Chem Soc 1811 1951.] The anhydrous compound has m 118o (after drying at high vacuum at 80o) and is also obtained by recrystallisation from pet ether or *C6H6 (70 parts) and drying at 78o/8mm. [UV: Badger et al. J Chem Soc 3199 1951.] IthasapKainH2Oof 4.857 (25o) or 5.02 (20o) and 4.27 in 50% aqueous EtOH (20o). [Albert et al. J Chem Soc 2240 1948]. [Beilstein 23 H 227, 23 II 235, 23/8 V 419.]

1,10-Phenanthroline hydrate Preparation Products And Raw materials

Raw materials

Preparation Products

1 10-PHENANTHROLINE-5 6-DIONE 97 4-Vinylcyclohexene dioxide
More
Less

1,10-Phenanthroline hydrate Suppliers

Americas 1 Australia 1 Austria 1 Belgium 1 Brazil 1 Canada 2 China 400 Czech Republic 3 Europe 4 France 3 Germany 8 India 29 Japan 8 Mexico 2 Poland 1 Russia 1 South Korea 1 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 24 United States 71 Global 566
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38632
Advantage
58
Eastar Chemical Corp
Tel
+1-8008982436 +86-13998381317
Email
manannan@chinaeastar.com
Country
United States
ProdList
376
Advantage
58
United States Biological
Tel
--
Fax
--
Email
sales@advtechind.com
Country
United States
ProdList
6075
Advantage
58
Alfa Chemistry
Tel
--
Fax
--
Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
Redox Scientific
Tel
--
Fax
--
Email
info@redoxsci.com
Country
United States
ProdList
2380
Advantage
58
LOBA FEINCHEMIE GMBH
Tel
--
Fax
--
Email
sales@loba.co.at
Country
United States
ProdList
72
Advantage
58
Lab Express International
Tel
--
Fax
--
Email
@labexpress.com
Country
United States
ProdList
307
Advantage
58
Selleck Chemicals LLC
Tel
--
Fax
--
Email
sales@selleckchem.com
Country
United States
ProdList
1848
Advantage
58
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
MD Chemicals
Tel
--
Fax
--
Email
info@mdchemicals.net
Country
United States
ProdList
158
Advantage
58
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
GFS Chemicals Inc
Tel
--
Fax
--
Email
service@gfschemicals.com
Country
United States
ProdList
2329
Advantage
58
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
HBCChem, Inc.
Tel
--
Fax
--
Email
Sales@hbcchem-inc.com
Country
United States
ProdList
887
Advantage
50
Bosgen Chemical Inc.
Tel
--
Fax
--
Email
sale@chemapi.com
Country
United States
ProdList
609
Advantage
30
Santa Cruz Biotechnology, Inc.
Tel
--
Fax
--
Email
scbt@scbt.com
Country
United States
ProdList
3597
Advantage
60
Anvia Chemicals, LLC
Tel
--
Fax
--
Email
sales@anviachem.com
Country
United States
ProdList
3933
Advantage
0
Sisco Research Laboratories Pvt. Ltd.
Tel
--
Fax
--
Email
srlmarketing@dishnetdsl.net
Country
United States
ProdList
1905
Advantage
64
HBCChem Inc.
Tel
--
Fax
--
Email
sales@hbcchem-inc.com
Country
United States
ProdList
4569
Advantage
30
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
ChemService Inc.
Tel
--
Fax
--
Country
United States
ProdList
6379
Advantage
68
ProChem, Inc.
Tel
--
Fax
--
Email
prochem1@aol.com
Country
United States
ProdList
1691
Advantage
66
Dudley Chemical Corp.
Tel
--
Fax
--
Email
dudley@dudley-chem.com
Country
United States
ProdList
687
Advantage
64
Naugra Export
Tel
--
Fax
--
Country
United States
ProdList
1332
Advantage
47
ACS Chemical, Inc.
Tel
--
Fax
--
Email
acsrenee@verizon.net
Country
United States
ProdList
271
Advantage
30
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
APAC Pharmaceutical, LLC
Tel
--
Fax
--
Email
sales@apacpharma.com
Country
United States
ProdList
6322
Advantage
38
Accord Corporation
Tel
--
Fax
--
Email
info@accordchem.com
Country
United States
ProdList
225
Advantage
42
TimTec Corporation
Tel
--
Fax
--
Country
United States
ProdList
1945
Advantage
58
M/S PANAMIT INTERNATIONAL
Tel
--
Fax
--
Email
sales@jyotichem.com
Country
United States
ProdList
312
Advantage
46
Baddley Chemicals, Inc.
Tel
--
Fax
--
Email
quotation@baddley.com
Country
United States
ProdList
178
Advantage
68
Sciencelab.com, Inc.
Tel
--
Fax
--
Email
accounting@sciencelab.com
Country
United States
ProdList
4159
Advantage
82
Lab Express
Tel
--
Fax
--
Email
sales@labexpress.com
Country
United States
ProdList
1577
Advantage
67
Loba Chemie Pvt. Ltd.
Tel
--
Fax
--
Country
United States
ProdList
1945
Advantage
71
J.T. Baker-A Division of Mallinckrodt Baker, Inc.
Tel
--
Fax
--
Country
United States
ProdList
1066
Advantage
82
Fisher Scientific
Tel
--
Fax
--
Email
sales@fishersci.com
Country
United States
ProdList
2337
Advantage
86
ASDI Incorporated
Tel
--
Fax
--
Email
customerservice@asdi.net
Country
United States
ProdList
6922
Advantage
67
ChromaDex
Tel
--
Fax
--
Email
sales@chromadex.com
Country
United States
ProdList
2501
Advantage
76
More
Less

View Lastest Price from 1,10-Phenanthroline hydrate manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
1,10-Phenanthroline hydrate 5144-89-8
Price
US $999.00-666.00/ton
Min. Order
1ton
Purity
99%
Supply Ability
5000
Release date
2024-08-20
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
O-Phenanthroline Monohydrate 5144-89-8
Price
US $180.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-23
Shandong Deshang Chemical Co., Ltd.
Product
1,10-Phenanthroline hydrate 5144-89-8
Price
US $10.00-7.00/kg
Min. Order
1kg
Purity
99.99%
Supply Ability
10 tons
Release date
2024-06-14

5144-89-8, 1,10-Phenanthroline hydrateRelated Search:

Bathocuproine p-Toluenesulfonic acid monohydrate o-Phenanthroline Chloral hydrate 1,7-PHENANTHROLINE Levofloxacin heMihydrate Citric acid monohydrate MELIBIOSE 5,6-Dimethyl-1,10-phenanthroline 5-CHLORO-1,10-PHENANTHROLINE Neocuproine 5-NITRO-1 10-PHENANTHROLINE HYDRATE & o-Phenanthroline monohydrochloride monohydrate 3,4,7,8-Tetramethyl-1,10-phenanthroline 4,7-Dimethyl-1,10-phenanthroline BATHOPHENANTHROLINEDISULFONIC ACID DISODIUM SALT TRIHYDRATE Bathophenanthroline BATHOCUPROINEDISULFONIC ACID DISODIUM SALT Phenanthroline Monohydrate

  • 1,10-PHENANTHROLINE H2O
  • 1,10-Phenanthroline monohydrate, reagent ACS
  • 1,10-Phenanthrolinemonhydrate
  • 1,10-Phenanthroline monohydrate, ACS
  • 1,10-Phenanthroline, ACS, 99%
  • 1,10-PHENANTHROLINE MONOHYDRATE extrapure AR
  • 1,10-Phenanthroline, Monohydrate, Reagent
  • 1,10-Phenanthroline Monohydrate [for Biochemical Research]
  • 1,10-PHENANTHROLINE AR
  • 1,10-PHENANTHROLINE AR (H2O)
  • 1,10-phenanthrolinemonorate
  • 1,10-Phenanthroline hydrate,99+%
  • 1,10-Phenanthroline Monohydrate,98%
  • o-Phenanthroline monohydrate, redox indicator, reagent grade, ACS
  • 1,10-Phenanthroline monohydrate p.a.
  • o-Phenanthroline Monohydrate, GR ACS
  • 1,10-Phenanthroline&nbsp
  • 1,10-Phenanthroline Monohydrate, 99+% 25GR
  • 1,10-Phenanthroline Monohydrate, 99+% 5GR
  • glaucescent fissistigma root P.E.
  • 1,10-Phenanthroline monohydrate≥ 99.5% (Titration)
  • O-phenanthroline indicator solution
  • 10-Phenanthroline monohydrate
  • 1,10- phenanthroline ferrous indicator
  • 1,10-Phenanthroline hydrate solution
  • 1,10-Phenanthroline monohydrate, 99%, indicator, ACS reagent
  • o-Phenanthroline - CAS 5144-89-8 - Calbiochem
  • 1,10-PHENANTHROLINE MONOHYDRATE, REAGENT (ACS)1,10-PHENANTHROLINE MONOHYDRATE, REAGENT (ACS)1,10-PHENANTHROLINE MONOHYDRATE, REAGENT (ACS)1,10-PHENANTHROLINE MONOHYDRATE, REAGENT (ACS)
  • 1,10-PHENANTHROLINE SOLUTION, 0.12% in Water1,10-PHENANTHROLINE SOLUTION, 0.12% in Water1,10-PHENANTHROLINE SOLUTION, 0.12% in Water
  • 1,10-PHENANTHROLINE 1HYD
  • 1,10-Phenathroline(Monohydrate)
  • 1,10-PHENANTHROLINE HYDRATE
  • 1,10-PHENANTHROLINE MONOHYDRATE
  • 1,10-PHENANTHROLINE MONOHYDRATE (O-)
  • ORTHO-PHENANTHROLINE
  • ORTHOPHENANTHROLINE MONOHYDRATE
  • O-PHENANTHROLINE MONOHYDRATE
  • O-PHENANTHROLINE HYDRATE
  • PHENYLANTHROLINE HYDRATE 1,10-
  • 1,10-phenanthrollne,monohydrate
  • 4,5-Phenanthrolinemonohydrate
  • 1 10-PHENANTHROLINE MONOHYDRATE 99% &
  • 1,10-PHENANTHROLINE MONOHYDRATE*ACS REAG ENT
  • 1,10-PHENANTHROLINE MONOHYDRATE, 99%, A. C.S. REAGENT
  • 1,10-Phenanthroline(Monohydrate)Gr
  • 1,10-PhenanthrolineGrMonohydrate-RedoxIndicator
  • 1,10-PhenanthrolineGrMonohydrate
  • 1,10-PHENANTHROLINE MONOHYDRATE, 99+%
  • Phenanthroline Monohydrate
  • Black bone vine extract
  • HISTOLOGICAL FIXATIVE A.F.A. HISTONORM
  • 1,10-Phenanthroline monohydrate ACS reagent, puriss. p.a., >=99.5% (calc. to the dried substance), for redox titration
  • 1,10-Phenanthroline monohydrate Vetec(TM) reagent grade
  • 1,10-PHENANTHROLINE 1H2O
  • Phenanthroline analytical grade
  • EGG YOLK (6X100ML)+TELLUR.(6X) Y-IRR.
  • 1,10-PhenanthrolineMonohydrate[forBiochemicalResearch]&gt
  • 1,10-Phenanthroline monohydrate, 98%, for analysis