ChemicalBook > CAS DataBase List > trace amine receptor 1
trace amine receptor 1
- Product Name
- trace amine receptor 1
- CAS No.
- 1043495-96-0
- Chemical Name
- trace amine receptor 1
- Synonyms
- tar1;TRAR1;TAAR1;rTAR1;snorf33;RO-5256390;RP11-295F4.9;RO-5256390,RO5256390;trace amine receptor 1;trace amine associated receptor 1
- CBNumber
- CB82907965
- Molecular Formula
- C13H18N2O
- Formula Weight
- 218.29
- MOL File
- 1043495-96-0.mol
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trace amine receptor 1 Property
- Boiling point:
- 330.9±25.0 °C(Predicted)
- Density
- 1.13±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- pka
- 8.58±0.70(Predicted)
- color
- White to off-white
- optical activity
- [α]/D 14 to 19°, c =1 in methanol
- biological source
- rabbit
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N-Bromosuccinimide Price
TRC
- Product number
- R637375
- Product name
- RO5256390
- Packaging
- 5mg
- Price
- $195
- Updated
- 2021/12/16
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trace amine receptor 1 Chemical Properties,Usage,Production
Uses
RO 5256390 is a trace amine-associated receptor 1(TAAR1) agonist which may be used as treatment of cocaine addiction.
Biological Activity
RO5256390 is an agonist of Trace amine-associated receptor 1 (TAAR1), a GPCR primarily found in the brain, expressed in areas where the major monoamine amine transmitters (DA and NE) are also present. RO5256390 is a selective TAAR1 agonist shown to be a negative regulator of dopamine transmission. It has antipsychotic activity in models of schizophrenia, reduces cocaineμs reinforcng effects, and blocks binge-eating disorder.
trace amine receptor 1 Preparation Products And Raw materials
Raw materials
Preparation Products
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