ChemicalBook > CAS DataBase List > OKADAIC ACID SODIUM SALT

OKADAIC ACID SODIUM SALT

Product Name
OKADAIC ACID SODIUM SALT
CAS No.
209266-80-8
Chemical Name
OKADAIC ACID SODIUM SALT
Synonyms
HALOCHONDRINE A;OKADAIC ACID SODIUM;Chlorfenapyr Impurity 6;OKADAIC ACID SODIUM SALT;BYHIFOCTDVNQQT-BWQUQSRCSA-M;HALOCHONDRINE A, SODIUM SALT;Mussel matrix with DSP toxins;Okadaic acid sodium salt (high purity);OKADAIC ACID SODIUM SALT, 98%, HIGH PURITY;9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIOFOLICIN
CBNumber
CB8300139
Molecular Formula
C44H67NaO13
Formula Weight
826.98
MOL File
209266-80-8.mol
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OKADAIC ACID SODIUM SALT Property

storage temp. 
-20°C
solubility 
Soluble in DMSO or ethanol
form 
film
color 
translucent
biological source
plant (Prorocentrum concavum)
Water Solubility 
water: 1mg/mL
DMSO: 20mg/mL
ethanol: 20mg/mL
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Safety

Hazard Codes 
T
Risk Statements 
23/24/25-38
Safety Statements 
26-36/37-45
RIDADR 
UN 3462 6.1/PG 1
WGK Germany 
3
HazardClass 
6.1
HS Code 
29321900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
O7760
Product name
Okadaic acid sodium salt from Prorocentrum concavum
Purity
≥90% (HPLC), film
Packaging
10μg
Price
$142
Updated
2025/07/31
Sigma-Aldrich
Product number
O7760
Product name
Okadaic acid sodium salt from Prorocentrum concavum
Purity
≥90% (HPLC), film
Packaging
25μg
Price
$222
Updated
2025/07/31
Sigma-Aldrich
Product number
O7760
Product name
Okadaic acid sodium salt from Prorocentrum concavum
Purity
≥90% (HPLC), film
Packaging
50μg
Price
$239.5
Updated
2025/07/31
Sigma-Aldrich
Product number
459620
Product name
Okadaic Acid, Sodium Salt
Purity
Water-soluble analog of Okadaic Acid. Inhibits protein phosphatases 1 and 2A.
Packaging
25μG
Price
$102
Updated
2025/07/31
Usbiological
Product number
O5800
Product name
Okadaic Acid, Sodium salt
Packaging
100ug
Price
$262
Updated
2021/12/16
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OKADAIC ACID SODIUM SALT Chemical Properties,Usage,Production

Chemical Properties

white to off-white solid

Uses

Potent inhibitor of serine/threonine-specific protein phosphatases 1 and 2A (PP1 and PP2A). Does not inhibit tyrosine or alkaline phosphatases

Biochem/physiol Actions

Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases. Does not inhibit tyrosine phosphatases, alkaline phosphatases or acid phosphatase. Known tumor promotor. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling.

in vivo

Okadaic acid sodium can be used to induce Alzheimer's disease models[6].

Induction of alzheimer's disease model[6]
Background
Okadaic acid sodium is a Ser/Thr phosphatase enzyme inhibitor that causes Tau hyperphosphorylation and induces the intracellular aggregation of neurofibrillary tangles.
Specific Modeling Methods
Mice: Wistar ? male ?-250-300 g
Administration: 100μg ? icv ? single dose
Modeling Indicators
Molecular changes: Induced increases in pTauser396 in the hippocampus.
Correlated Product(s): /
Opposite Product(s): /

IC 50

PP1: 15-50 nM (IC50); PP2A: 0.1-0.3 nM (IC50); PP3: 3.7-4 nM (IC50); PP4: 0.1 nM (IC50); PP5: 3.5 nM (IC50); PP2B: ~4000 nM (IC50); PP7: >1000 nM (IC50)

storage

Store at -20°C (desiccate)

OKADAIC ACID SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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OKADAIC ACID SODIUM SALT Suppliers

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209266-80-8, OKADAIC ACID SODIUM SALTRelated Search:

MICROCYSTIN-LR OKADAIC ACID POTASSIUM SALT CALYCULIN A MICROCYSTIN YR NODULARIN TAUTOMYCIN OKADAIC ACID AMMONIUM SALT OKADAIC ACID SODIUM SALT 98+% TRANS-2-BUTENAL DIETHYL ACETAL 2-(ALLYLOXY)TETRAHYDROPYRAN 1,7-DIOXASPIRO[5.5]UNDECANE Okadaic Acid sodium salt (dinoflagellate marine toxin), Protein Phosphatase Inhibitor (PP-1 & PP-2A), Apoptosis Inducer, 0.827kD 6-BUTYL-3,6-DIHYDRO-2,4-DIMETHYL-2H-PYRAN Acrolein diethyl acetal OKADAIC ACID SODIUM SALT

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  • Okadaic Acid Sodium Salt DISCONTINUED, offer O515500
  • (2R)-3-[(2S,6R,8S,11R)-2-[(E,2R)-4-[(2S,2''R,4R,4aS,6R,8aR)-4-hydroxy-2-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl]-3-methylidenespiro[4a,7,8,8a-tetrahydro-4H-pyrano[3,2-b]pyran-6,5''-oxolane]-2''-yl]but-3-en-2-yl]
  • Chlorfenapyr Impurity 6
  • Okadaic acid sodium salt from <i>Prorocentrum concavum</i>
  • Mussel matrix with DSP toxins
  • Okadaic Acid (sodium salt) solution in methanol (6 μg in 0.5 mL)
  • 209266-80-8
  • C44H67NaO13
  • C44H67O13Na
  • Inhibitor