ANTI-MOESIN
- Product Name
- ANTI-MOESIN
- Chemical Name
- ANTI-MOESIN
- Synonyms
- ANTI-MOESIN;MONOCLONAL ANTI-MOESIN;ANTI-EZRIN/RADIXIN/MOESIN ANTIBODY;Anti-MSN antibody produced in rabbit;Anti-Moesin antibody produced in goat;Monoclonal Anti-MSN antibody produced in mouse;Anti-Membrane-organizing extension spike protein;Monoclonal Anti-Moesin antibody produced in mouse
- CBNumber
- CB8301257
- Formula Weight
- 0
- MOL File
- Mol file
ANTI-MOESIN Property
- storage temp.
- -20°C
- form
- buffered aqueous solution
- biological source
- rabbit
Safety
- WGK Germany
- -
- Storage Class
- 10 - Combustible liquids
N-Bromosuccinimide Price
- Product number
- WH0004478M13
- Product name
- Monoclonal Anti-MSN antibody produced in mouse
- Purity
- clone 4B8, purified immunoglobulin, buffered aqueous solution
- Packaging
- 100 μg
- Price
- $406
- Updated
- 2025/07/31
- Product number
- SAB1410798
- Product name
- Anti-MSN antibody produced in rabbit
- Purity
- purified immunoglobulin, buffered aqueous solution
- Packaging
- 100μG
- Price
- $541
- Updated
- 2025/07/31
- Product number
- M7060
- Product name
- Monoclonal Anti-Moesin antibody produced in mouse
- Purity
- clone 38/87, purified immunoglobulin, buffered aqueous solution
- Packaging
- 0.2ML
- Price
- $545
- Updated
- 2025/07/31
- Product number
- HPA011227
- Product name
- Anti-MSN antibody produced in rabbit
- Purity
- Prestige Antibodies<SUP>®</SUP> Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
- Packaging
- 100 μL
- Price
- $555
- Updated
- 2025/07/31
- Product number
- HPA011135
- Product name
- Anti-MSN antibody produced in rabbit
- Purity
- Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
- Packaging
- 100μL
- Price
- $555
- Updated
- 2025/07/31
ANTI-MOESIN Chemical Properties,Usage,Production
Uses
Mouse monoclonal clone 38/87 anti-Moesin antibody may be used for ELISA, immunoblotting (a closely spaced doublet of 78/80 kDa) immunoprecipitation, immunohistochemistry (reported for frozen sections and for formalin-fixed paraffin-embedded sections following boiling in 0.01M citrate buffer pH 6), immunocytochemistry (3.7% paraformaldehyde, 0.1% Triton X-100), flow cytometry (3-3.7% paraformaldehyde, 0.1-0.25% Triton X-100) and electron microscopy. The intensity of the fainter doublet‘s upper band seen in immunoblotting varies depending on the tissue. The antibody has been used to inhibit both the binding of proteoheparan sulfate to smooth muscle cells, and the infectivity of measles virus.
Biological Activity
The ERM (ezrin-radixin-moesin) proteins, members of the talin-protein 4.1- merlin/schwannomin superfamily, are general cross-linkers between the plasma membrane and actin filaments. They provide such links through their N-terminal halves th at associate with integral membrane proteins either directly or indirectly through adapter molecules, and through their C-terminal halves th at associate with F-actin. ERM proteins are involved not only in cytoskeletal organization but also in signal transduction and apoptosis. Because their expression is regulated in a tissue-specific manner, each ERM protein has been proposed to have unique functions. There is approximately 80% homology between moesin, ezrin and radixin. These proteins are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures. However, moesin (in contrast to radixin and ezrin) is strongly expressed in endothelium of vessels, in T and B lymphocytes, in basal layers of squamous epithelium and glandular ducts, and in cells of carcinoma and mesothelioma. Moesin is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines. It is overexpressed in some estrogen receptor (ER)-negative cell lines but absent from ER-positive ones, suggesting th at it may play a role in the invasiveness and pattern of metastasis characteristic of ER-negative breast cancers.
ANTI-MOESIN Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-MOESIN Suppliers
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- 021-61415566 800-8193336
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- China
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