ACETOACETYL COENZYME A SODIUM SALT HYDRATE
- Product Name
- ACETOACETYL COENZYME A SODIUM SALT HYDRATE
- CAS No.
- 1420-36-6
- Chemical Name
- ACETOACETYL COENZYME A SODIUM SALT HYDRATE
- Synonyms
- ACETOACETYL-COANA3;ACETOACETYL-COANA3 TRIHYDRATE;ACETOACETYL COENZYME A SODIUM SALT HYDRATE;ACETOACETYL COENZYME A TRISODIUM SALT TRIHYDRATE
- CBNumber
- CB8302522
- Molecular Formula
- C25H43N7Na3O21P3S
- Formula Weight
- 971.6
- MOL File
- Mol file
ACETOACETYL COENZYME A SODIUM SALT HYDRATE Property
- storage temp.
- −20°C
- solubility
- H2O: 50 mg/mL, clear, colorless to faintly yellow
Safety
- WGK Germany
- 3
- F
- 10-21
N-Bromosuccinimide Price
- Product number
- 21219
- Product name
- Acetoacetyl Coenzyme A (sodium salt hydrate)
- Packaging
- 1mg
- Price
- $81
- Updated
- 2024/03/01
- Product number
- 21219
- Product name
- Acetoacetyl Coenzyme A (sodium salt hydrate)
- Packaging
- 10mg
- Price
- $364
- Updated
- 2024/03/01
- Product number
- 21219
- Product name
- Acetoacetyl Coenzyme A (sodium salt hydrate)
- Packaging
- 5mg
- Price
- $202
- Updated
- 2024/03/01
ACETOACETYL COENZYME A SODIUM SALT HYDRATE Chemical Properties,Usage,Production
Description
Acetoacetyl-coenzyme A (acetoacetyl-CoA) is a precursor to HMG-CoA in the isoprenoid pathway. It is reversibly converted to acetyl-CoA by acetoacetyl-CoA thiolase in the mitochondria. Acetoacetyl-CoA thiolase (T2) deficiency results in a build-up of ketone bodies leading to intermittent ketoacidosis. Acetoacetyl-CoA is also an intermediate in the microbial biosynthesis of polyhydroxybutyrate.
References
[1] OCHOA S. Enzymes of fatty acid metabolism: a commentary on “Enzymes of Fatty Acid Metabolism”.[J]. Biochimica et biophysica acta, 1989, 1000: 279-280.
[2] MIZIORKO H M. Enzymes of the mevalonate pathway of isoprenoid biosynthesis[J]. Archives of biochemistry and biophysics, 2011, 505 2: Pages 131-143. DOI: 10.1016/j.abb.2010.09.028
[3] R S DAUM. An inherited disorder of isoleucine catabolism causing accumulation of alpha-methylacetoacetate and alpha-methyl-beta -hydroxybutyrate, and intermittent metabolic acidosis.[J]. Pediatric Research, 1973, 7 3: 149-160. DOI: 10.1203/00006450-197303000-00007
[4] TOSHIYUKI FUKAO . The Clinical Phenotype and Outcome of Mitochondrial Acetoacetyl-CoA Thiolase Deficiency (β-Ketothiolase or T2 Deficiency) in 26 Enzymatically Proved and Mutation-Defined Patients[J]. Molecular genetics and metabolism, 2001, 72 2: Pages 109-114. DOI: 10.1006/mgme.2000.3113
[5] NICOLAS JACQUEL . Isolation and purification of bacterial poly(3-hydroxyalkanoates)[J]. Biochemical Engineering Journal, 2008, 39 1: Pages 15-27. DOI: 10.1016/j.bej.2007.11.029
ACETOACETYL COENZYME A SODIUM SALT HYDRATE Preparation Products And Raw materials
Raw materials
Preparation Products
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