1-(1-(3-methoxyphenyl)-7-propoxyindolizin-3-yl)ethanone
- Product Name
- 1-(1-(3-methoxyphenyl)-7-propoxyindolizin-3-yl)ethanone
- CAS No.
- 1693766-04-9
- Chemical Name
- 1-(1-(3-methoxyphenyl)-7-propoxyindolizin-3-yl)ethanone
- Synonyms
- GSK8573;gsk5873;gsk-5873;GSK8573, 10 mM in DMSO;GSK-5873;GSK5873;GSK 8573;GSK8573;GSK-8573;GSK 8573;QBGNWWJANJWNY-UHFFFAOYSA-N;GSK-8573(negative control of GSK-2801);1-(1-(3-methoxyphenyl)-7-propoxyindolizin-3-yl)ethanone;1-(1-(3-Methoxyphenyl)-7-propoxyindolizin-3-yl)ethan-1-one
- CBNumber
- CB83041732
- Molecular Formula
- C20H21NO3
- Formula Weight
- 323.39
- MOL File
- 1693766-04-9.mol
1-(1-(3-methoxyphenyl)-7-propoxyindolizin-3-yl)ethanone Property
- Density
- 1.12±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 25 mg/mL (77.31 mM)
- form
- Solid
- color
- Light yellow to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 43560
- Product name
- GSK8573
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2026/04/30
- Product number
- 43560
- Product name
- GSK8573
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $96
- Updated
- 2026/04/30
- Product number
- 43560
- Product name
- GSK8573
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $160
- Updated
- 2026/04/30
- Product number
- 43560
- Product name
- GSK8573
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $280
- Updated
- 2026/04/30
- Product number
- CS-0028596
- Product name
- GSK8573
- Purity
- 98.01%
- Packaging
- 25mg
- Price
- $360
- Updated
- 2021/12/16
1-(1-(3-methoxyphenyl)-7-propoxyindolizin-3-yl)ethanone Chemical Properties,Usage,Production
Uses
GSK8573 is an inactive control compound for GSK2801 (acetyl-lysine competitive inhibitor of BAZ2A and BAZ2B bromodomains). GSK8573 has binding activity to BRD9 with a Kd value of 1.04 μM and is inactive against BAZ2A/B and other bromodomain familiy. GSK8573 can be used as a structurally related negative control compound in biological experiments[1].
IC 50
BRD9: 1.04 μM (Kd)
References
[1] Chen P, et al. Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B. J Med Chem. 2016 Feb 25;59(4):1410-24. DOI:10.1021/acs.jmedchem.5b00209
1-(1-(3-methoxyphenyl)-7-propoxyindolizin-3-yl)ethanone Preparation Products And Raw materials
Raw materials
Preparation Products
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