Entecavir Impurity

Product Name: Entecavir Impurity
CAS No.: 1333204-94-6
Chemical Name: Entecavir Impurity
Synonyms: Entecavir Hydrate IMP;(1R,3S,4S)-ent-Entecavir;Entecavir (R,S,S)-Isomer;rel-2-Amino-9-((1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-3,9-dihydro-6H-purin-6-one;6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-, rel-
CBNumber: CB83050248
Molecular Formula: C12H15N5O3
Formula Weight: 277.28
MOL File: 1333204-94-6.mol

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Entecavir Impurity Property

Boiling point:: 661.4±65.0 °C(Predicted)
Density: 1.81±0.1 g/cm3(Predicted)
pka: 14.22±0.60(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: E558915
Product name: (1R,3S,4S)-Entecavir
Packaging: 10mg
Price: $10240
Updated: 2021/12/16

TRC

Product number: E558915
Product name: (1R,3S,4S)-Entecavir
Packaging: 25mg
Price: $13390
Updated: 2021/12/16

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Entecavir Impurity Chemical Properties,Usage,Production

Uses

(1R,3S,4S)-Entecavir is an impurity of Entecavir (E558900).

Definition

ChEBI: Entecavir (anhydrous) is guanine substituted at the 9 position by a 4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl group. A synthetic analogue of 2'-deoxyguanosine, it is a nucleoside reverse transcriptase inhibitor with selective antiviral activity against hepatitis B virus. Entecavir is phosphorylated intracellularly to the active triphosphate form, which competes with deoxyguanosine triphosphate, the natural substrate of hepatitis B virus reverse transcriptase, inhibiting every stage of the enzyme's activity, although it has no activity against HIV. It is used for the treatment of chronic hepatitis B. It has a role as an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor and an antiviral drug. It is a member of 2-aminopurines, an oxopurine, a primary alcohol and a secondary alcohol.

Entecavir Impurity Preparation Products And Raw materials

Raw materials

Preparation Products

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Entecavir Impurity Suppliers

China 30 India 1 United States 1 Global 32

Shandong Boluoda Biological Technology Co., Ltd.

Tel: 0531-58190570 15863796298
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ProdList: 332
Advantage: 58

Lianyungang TengFa Biological Technology Co. Ltd

Tel: 0518-85475186 18705131893
Fax: 0518-85475186
Email: wang666xt@163.com
Country: China
ProdList: 351
Advantage: 55

Pharmacodia (Beijing) Co.,Ltd

Tel: +86-400-851-9921
Fax: +86-10-82826195
Email: sales@pharmacodia.com
Country: China
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Advantage: 55

Roark Standards

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Country: China
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Hubei Yangxin Medical Technology Co., Ltd.

Tel: 15374522761
Fax: QQ:2853117752
Email: 3003392093@qq.com
Country: China
ProdList: 7851
Advantage: 55

Shenzhen SUNGENING Bio-Medical Co., Ltd.

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Shenzhen Polymeri Biochemical Technology Co., Ltd.

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Shenzhen Popeye Biotechnology Co. Ltd.

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Guangzhou Dreampharm Biotechnology Co., Ltd.

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Country: China
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Hubei Moco Chemical Co., Ltd.

Tel: 18627756402
Fax: QQ：3001051413
Email: 3001051413@qq.com
Country: China
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View Lastest Price from Entecavir Impurity manufacturers

Career Henan Chemical Co

Product: Entecavir Impurity 1333204-94-6
Price: US $1.00/g
Min. Order: 1g
Purity: 99.99%
Supply Ability: 200kg
Release date: 2019-12-23

1333204-94-6, Entecavir ImpurityRelated Search:

(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol 6-(Benzyloxy)-9-((1S,3S)-4-(benzyloxy)-3-((benzyloxy)methyl)-2-methylenecyclopentyl)-N-((4-methoxyphenyl)diphenylmethyl)-9H-purin-2-amine 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]- (1R,3R,4R)-Entecavir (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(benzyloxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanone 2-AMino-1,9-dihydro-9-[(1S,3R,4S)-4-(hydroxydiMethylsilyl)-3-(hydroxyMethyl)-2-Methylenecyclopentyl]-6H-purin-6-one Entecavir (1S, 2R)-2-(Benzyloxymethyl)-1-hydroxy-3-cyclopentene Entecavir Impurity 17(Entecavir EP Impurity C) 6-O-Benzyl-4-dehydroxy-4-diMethylphenylsilyl Entecavir (1S,3S,4R)-Entecavir 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one Entecavir Impurity 5 2-amino-9-((1R,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1,9-dihydro-6H-purin-6-one hydrate 2-amino-9-((1S,3S,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1,9-dihydro-6H-purin-6-one (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol (1'S,3'S,4'S)-Entecavir IsoMer Entecavir Impurity 32

Entecavir Hydrate IMP

(1R,3S,4S)-ent-Entecavir

6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-, rel-

Entecavir (R,S,S)-Isomer

rel-2-Amino-9-((1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-3,9-dihydro-6H-purin-6-one

1333204-94-6

870614-02-7