Azido-PEG2-CH2CO2tBu

Product Name: Azido-PEG2-CH2CO2tBu
CAS No.: 251564-45-1
Chemical Name: Azido-PEG2-CH2CO2tBu
Synonyms: N3-AEEA-OtBu;CAS_251564-45-1;N3-PEG2-CH2COOtBu;Azido-PEG2-C1-Boc;Azido-PEG2-CH2COOtBu;Azido-PEG2-CH2CO2tBu;Azido-PEG2-t-butyl acetate;Azido-PEG2-CH2COOH t-Bu Ester;tert-butyl 8-azido-3,6-dioxaoctanoate;tert-butyl 2-(2-(2-azidoethoxy)ethoxy)acetate
CBNumber: CB83062346
Molecular Formula: C10H19N3O4
Formula Weight: 245.27556
MOL File: 251564-45-1.mol

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Azido-PEG2-CH2CO2tBu Property

storage temp.: Storage temp. 2-8°C
solubility: Soluble in DMSO, DCM, DMF
form: Liquid
color: Colorless to light yellow

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Safety

HS Code: 9999999999

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific

Product number: AMTGC627
Product name: 8-Azido-3,6-dioxaoctanoicacidtert-butylester
Packaging: 100mg
Price: $49
Updated: 2021/12/16

Chem-Impex

Product number: 30728
Product name: 8-Azido-3,6-dioxaoctanoicacidtert-butylester,≥95%(GC)
Purity: ≥95%(GC)
Packaging: 100MG
Price: $58.24
Updated: 2021/12/16

Chem-Impex

Product number: 30728
Product name: 8-Azido-3,6-dioxaoctanoicacidtert-butylester,≥95%(GC)
Purity: ≥95%(GC)
Packaging: 250MG
Price: $110.66
Updated: 2021/12/16

Chem-Impex

Product number: 30728
Product name: 8-Azido-3,6-dioxaoctanoicacidtert-butylester,≥95%(GC)
Purity: ≥95%(GC)
Packaging: 1G
Price: $326.14
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1148
Product name: Azido-PEG2-CH2CO2tBu
Packaging: 100mg
Price: $546
Updated: 2021/12/16

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Azido-PEG2-CH2CO2tBu Chemical Properties,Usage,Production

Description

Azido-PEG2-CH2CO2-t-Bu is a azide containing PEG molecule with a t-butyl ester. The azide group is reactive with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Chemical Properties

Colorless oil

Uses

Azido-PEG2-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG2-C1-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azido-PEG2-CH2CO2tBu Preparation Products And Raw materials

Raw materials

Preparation Products

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Azido-PEG2-CH2CO2tBu Suppliers

China 41 United Kingdom 1 United States 4 Global 46

Shanghai Topbiochem Technology Co., Ltd

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Hunan HuaTeng Pharmaceutical Co., Ltd.,

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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

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Borenpharm Co., Ltd

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Zhengzhou Acme Chemical Co., Ltd.

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Amatek Scientific Co. Ltd.

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SHANGHAI FDC-CHEMICAL CO.,LTD

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Henan Alfachem Co.,Ltd.

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Alpha Biopharmaceuticals Co., Ltd

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View Lastest Price from Azido-PEG2-CH2CO2tBu manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: N3-PEG2-CH2COOtBu 251564-45-1
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
Release date: 2026-02-04

251564-45-1, Azido-PEG2-CH2CO2tBuRelated Search:

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Azido-PEG2-t-butyl acetate

tert-butyl 8-azido-3,6-dioxaoctanoate

Azido-PEG2-CH2CO2tBu

8-Azido-3,6-dioxaoctanoic acidtert-butyl ester≥ 95% (GC)

N3-AEEA-OtBu

N3-PEG2-CH2COOtBu

CAS_251564-45-1

Azido-PEG2-C1-Boc

8-Azido-3,6-dioxaoctanoic acid tert-butyl ester

Azido-PEG2-CH2COOtBu

tert-butyl 2-(2-(2-azidoethoxy)ethoxy)acetate

Azido-PEG2-CH2COOH t-Bu Ester

N3-PEG2-CH2COOtBu/Acetic acid, 2-[2-(2-azidoethoxy)ethoxy]-, 1,1-dimethylethyl ester

251564-45-1

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