H-VAL-NH2 HCL

Product Name: H-VAL-NH2 HCL
CAS No.: 3014-80-0
Chemical Name: H-VAL-NH2 HCL
Synonyms: L-Val-NH2;Val-Nh2.Hcl;H-Val-NH HCl;L-Val-NH2·HCl;VALINE-NH2 HC;H-VAL-NH2 HCL;VALINE-NH2 HCL;H-L-VAL-NH2 HCL;L-Valinamide HCl;L-VALINE AMIDE HCL
CBNumber: CB8306409
Molecular Formula: C5H12N2O.ClH
Formula Weight: 152.62
MOL File: 3014-80-0.mol

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H-VAL-NH2 HCL Property

Melting point:: 266-270 °C(lit.)
refractive index: 27 ° (C=1, H2O)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Soluble in methanol (50 mg/ ml-clear, colorless solution).
form: Solid
color: White to Almost white
optical activity: [α]25/D +25.8°, c = 1 in H2O
InChI: InChI=1/C5H12N2O.ClH/c1-3(2)4(6)5(7)8;/h3-4H,6H2,1-2H3,(H2,7,8);1H/t4-;/s3
InChIKey: XFCNYSGKNAWXFL-NDILARRWNA-N
SMILES: [C@@H](N)(C(=O)N)C(C)C.Cl |&1:0,r|

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Safety

Safety Statements: 24/25
WGK Germany: 3
HS Code: 29241990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 459232
Product name: L-Valinamide hydrochloride
Purity: 97%
Packaging: 5g
Price: $54.82
Updated: 2025/07/31

TCI Chemical

Product number: V0102
Product name: L-Valinamide Hydrochloride
Purity: >98.0%(N)(T)
Packaging: 5g
Price: $29
Updated: 2025/07/31

TCI Chemical

Product number: V0102
Product name: L-Valinamide Hydrochloride
Purity: >98.0%(N)(T)
Packaging: 25g
Price: $84
Updated: 2025/07/31

TRC

Product number: V094210
Product name: L-ValineAmide
Packaging: 10g
Price: $120
Updated: 2021/12/16

Chem-Impex

Product number: 03166
Product name: L-Valineamidehydrochloride,≥99%(HPLC)
Purity: ≥99%(HPLC)
Packaging: 5G
Price: $23.3
Updated: 2021/12/16

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H-VAL-NH2 HCL Chemical Properties,Usage,Production

Chemical Properties

Crystalline

Uses

L-Valine Amide is a reagent used in the synthesis of alkylpyrazines. Also used in the synthesis of elastase inhibitory activity.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

72-18-4

7732-18-5

75-24-1

3014-80-0

Preparation of Example 9 (S)-2-Amino-3-methylbutyramide hydrochloride: anhydrous ammonia was passed into 150 mL of cooled dichloromethane (ice bath) at 0°C until the solution was saturated. The mixture was cooled to 5°C and trimethylaluminum (136.2 mL of a 2M hexane solution, 272.4 mmol) was added slowly and dropwise under nitrogen protection. The resulting turbid solution was warmed to room temperature and stirred for 22 hours. L-valine (10.6 g, 90.79 mmol) was added in batches and stirring was continued at room temperature for 18 hours. The reaction mixture was cooled to 0 °C (ice-water bath) and 190 mL of 6N hydrochloric acid was added slowly and dropwise until the pH reached 2. The mixture was warmed to room temperature and stirred for 2 h. Subsequently, the pH was adjusted to 11-12 with 10% aqueous sodium hydroxide. 100 mL of dichloromethane and 100 mL of water were added to the alkaline solution, the organic layer was separated, dried over magnesium sulfate and concentrated to dryness under reduced pressure. The residue was dissolved in 100 mL of dichloromethane and acidified by passing hydrogen chloride gas. The solid formed was collected by filtration and dried under reduced pressure to give 6.8 g (49% yield) of L-valine amide hydrochloride with melting point 258°-260°C. IR (Nujol, cm-1 ) showed C=O (1686) and N-H (3387,3241) absorption peaks.1H NMR and 13C NMR (CDCl3 ) data were consistent with the target product. Elemental analysis (C5H13ClN2O) Calculated values: C, 39.35; H, 8.59; N, 18.35; Cl, 23.23; Measured values: C, 39.82; H, 8.52; N, 18.40; Cl, 23.13. Mass spectra (MS): m/e 117 (M+-Cl).

References

[1] Patent: US5643855, 1997, A

H-VAL-NH2 HCL Preparation Products And Raw materials

Raw materials

Preparation Products

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H-VAL-NH2 HCL Suppliers

Belgium 1 Canada 1 China 240 Europe 1 France 1 Germany 6 India 11 Japan 8 Spain 1 Switzerland 4 The Netherlands 1 United Kingdom 8 United States 41 Global 324

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View Lastest Price from H-VAL-NH2 HCL manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: H-VAL-NH2 HCL 3014-80-0
Price: US $25.00/kg
Min. Order: 100kg
Purity: 99.5%
Supply Ability: 100 mt
Release date: 2024-11-26

Career Henan Chemical Co

Product: H-VAL-NH2 HCL 3014-80-0
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2018-12-24

Career Henan Chemical Co

Product: H-VAL-NH2 HCL 3014-80-0
Price: US $100.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2018-07-27

3014-80-0, H-VAL-NH2 HCLRelated Search:

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L-VALINAMIDE HYDROCHLORIDE 3014-80-0

H-VAL-NH2 HCL USP/EP/BP

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Specialty Synthesis

Peptide Synthesis

Valine

Amino Acid Derivatives

Amino Acids and Derivatives

Amino hydrochloride

Amino Acid Derivatives

Amino Acids

Peptide Synthesis

Valine