Uses Description
ChemicalBook > CAS DataBase List > Methyl 2-phenylacetoacetate

Methyl 2-phenylacetoacetate

Uses Description
Product Name
Methyl 2-phenylacetoacetate
CAS No.
16648-44-5
Chemical Name
Methyl 2-phenylacetoacetate
Synonyms
BMK Glycidate;Benzeneacetic;Methyl 3-oxo-2-phenylbutanoate;BMK glycidate oil;Benzeneacetic acid, a-acetyl-, methyl ester;PBMK;BMK PRICE;bmk factory;bmk white powder;BMK CHINA FACTORY
CBNumber
CB83067497
Molecular Formula
C11H12O3
Formula Weight
192.21
MOL File
16648-44-5.mol
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Methyl 2-phenylacetoacetate Property

Melting point:
58.5-59.0 °C
Boiling point:
92-96 °C(Press: 0.6 Torr)
Density 
1?+-.0.06 g/cm3(Predicted)
solubility 
DMF: 30 mg/ml; DMSO: 50 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 50 mg/ml; Methanol: 1 mg/ml
form 
A crystalline solid
pka
10.67±0.46(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
28352
Product name
Methyl 2-phenylacetoacetate
Packaging
5mg
Price
$150
Updated
2023/06/20
AK Scientific
Product number
3810CU
Product name
Methylalpha-acetylphenylacetate
Packaging
5mg
Price
$268
Updated
2021/12/16
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Methyl 2-phenylacetoacetate Chemical Properties,Usage,Production

Uses

Benzeneacetic acid, a-acetyl-, methyl ester can be used as a pharmaceutical raw material.

Description

Methyl 2-phenylacetoacetate is an analytical reference standard categorized as a precursor in the synthesis of amphetamines and methamphetamines. This product is intended for research and forensic applications.
The Drug Enforcement Administration is proposing the control of the chemical methyl alpha-phenylacetoacetate (also known as MAPA; methyl 3-oxo-2-phenylbutanoate; methyl 2-phenylacetoacetate; [alpha]-acetyl-benzeneacetic acid, methyl ester; and CAS Number: 16648-44-5) and its optical isomers as a list I chemical under the Controlled Substances Act (CSA). Methyl alpha-phenylacetoacetate is used in clandestine laboratories to illicitly manufacture the schedule II controlled substances phenylacetone (also known as phenyl-2-propanone or P2P), methamphetamine, and amphetamine and is important to the manufacture of these controlled substances.

Description

Methyl 2-phenylacetoacetate (Item No. 28352) is an analytical reference standard categorized as a precursor in the synthesis of amphetamines and methamphetamines. This product is intended for research and forensic applications.

Uses

D1, D2 dopamine receptor antagonist; butyrophenone antipsychotic and anti-emetic. Droperidol is a potent antagonist of dopamine subtype 2 receptor. It is an antipsychotic, which is used to treat acute behavioral anomalies. It helps to manage postoperative nausea and vomiting. Endogenous κ1b opioid receptor agonist.

Preparation

Methyl phenyldiazoacetate, precursor to cyclopropanation agents, is prepared by treating methyl phenylacetate with p-acetamidobenzenesulfonyl azide in the presence of base.

Methyl 2-phenylacetoacetate Preparation Products And Raw materials

Raw materials

Preparation Products

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