Cuspin-1

Product Name: Cuspin-1
CAS No.: 337932-29-3
Chemical Name: Cuspin-1
Synonyms: Cuspin-1;Cuspin 1,Cuspin1;Cuspin-1 >=98% (HPLC);(5-Bromo-3-pyridinyl)(4-methylphenyl)methanone;Methanone, (5-bromo-3-pyridinyl)(4-methylphenyl)-
CBNumber: CB83067543
Molecular Formula: C13H10BrNO
Formula Weight: 276.1286
MOL File: 337932-29-3.mol

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Cuspin-1 Property

storage temp.: Store at -20°C
solubility: DMF: 25 mg/mL; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 16 mg/mL; Ethanol: 1 mg/mL
form: A crystalline solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 18526
Product name: Cuspin-1
Purity: ≥98%
Packaging: 5mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 18526
Product name: Cuspin-1
Purity: ≥98%
Packaging: 10mg
Price: $95
Updated: 2024/03/01

Cayman Chemical

Product number: 18526
Product name: Cuspin-1
Purity: ≥98%
Packaging: 25mg
Price: $208
Updated: 2024/03/01

Cayman Chemical

Product number: 18526
Product name: Cuspin-1
Purity: ≥98%
Packaging: 50mg
Price: $384
Updated: 2024/03/01

TRC

Product number: C845005
Product name: Cuspin1
Packaging: 10mg
Price: $85
Updated: 2021/12/16

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Cuspin-1 Chemical Properties,Usage,Production

Description

The Survival of Motor Neurons (SMN) protein participates in RNA splicing. Decreases in SMN, typically a consequence of defects in the smn1 gene, result in the death of motor neurons and lead to the neurodegenerative disease, spinal muscular atrophy (SMA). Cuspin-1 is a small molecule upregulator of SMN that has been shown in vitro to increase levels of SMN in SMA patient fibroblasts by 50% at 18 μM. Its mechanism of action is thought to involve increased phosphorylation of ERK to initiate Ras-Raf-MEK signaling, which results in an increased rate of SMN translation.

Uses

Cuspin 1 is used in cuspin-1 characterization and regulation of SMN protein via Ras signaling in spinal muscular atropy.

Cuspin-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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Cuspin-1 Suppliers

China 30 United Kingdom 1 United States 5 Global 36

BOC Sciences

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Lynnchem

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Novachemistry

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Shanghai Hongye Biotechnology Co. Ltd

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TargetMol Chemicals Inc.

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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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337932-29-3, Cuspin-1Related Search:

Cuspin-1

Methanone, (5-bromo-3-pyridinyl)(4-methylphenyl)-

Cuspin-1 >=98% (HPLC)

Cuspin 1,Cuspin1

(5-Bromo-3-pyridinyl)(4-methylphenyl)methanone

337932-29-3