TRANS-DECAHYDROISOQUINOLINE Property

Boiling point:

87 °C / 12mmHg

Density 

0,93 g/cm³

pka

11.84±0.20(Predicted)

Safety

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

TRANS-DECAHYDROISOQUINOLINE Chemical Properties,Usage,Production

Purification Methods

This is purified as the cis-isomer above. The trans-picrate has m 175-176o, and the trans-hydrochloride has m 221-222o and has IR (KBr) 2930, 3800, 1589, 1450, 1400, 1070, 952, 837 cm-1 . The pure free base is prepared as above max and had IR (film) 2920, 2820, 2720, 2560, 1584, 1470, 1445, 1415, 1395, 1315, 1300, 1135, 1080, 1020, 990, 873 cm. The 1HNMR in CDCl3 is characteristically different from that of the cis-isomer. (references as above and Helfer Helv Chim Acta 9 818 1926). [Beilstein 20 II 73, 20 III/IV 2026.]