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MI-136

Product Name
MI-136
CAS No.
1628316-74-4
Chemical Name
MI-136
Synonyms
MI-136;CS-2162;MI136;MI 136;HY-19319 (MI 136;MI-136;HY-19319 (MI 136; MI136);;5-((4-((6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)methyl)-1H-in;5-[[4-[[6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-1H-indole-2-carbonitrile;5-((4-((6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)methyl)-1H-indole-2-carbonitrile;1H-Indole-2-carbonitrile, 5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-;PPI,MI 136,Apoptosis,inhibit,MI136,Inhibitor,CRPC,castration,cancer,resistant,MI-136,Androgen Receptor,Epigenetic Reader Domain,prostate
CBNumber
CB83121119
Molecular Formula
C23H21F3N6S
Formula Weight
470.51
MOL File
1628316-74-4.mol
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MI-136 Property

Boiling point:
654.9±55.0 °C(Predicted)
Density 
1.45±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 10 mg/ml
form 
A crystalline solid
pka
14.20±0.30(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
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N-Bromosuccinimide Price

Cayman Chemical
Product number
19245
Product name
MI-136
Purity
≥98%
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
19245
Product name
MI-136
Purity
≥98%
Packaging
5mg
Price
$161
Updated
2024/03/01
Cayman Chemical
Product number
19245
Product name
MI-136
Purity
≥98%
Packaging
10mg
Price
$283
Updated
2024/03/01
Cayman Chemical
Product number
19245
Product name
MI-136
Purity
≥98%
Packaging
25mg
Price
$618
Updated
2024/03/01
ChemScene
Product number
CS-5526
Product name
MI-136
Purity
98.64%
Packaging
50mg
Price
$650
Updated
2021/12/16
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MI-136 Chemical Properties,Usage,Production

Description

MI-136 is an inhibitor of the menin-MLL interaction (IC50 = 31 nM; Kd = 23.6 nM). By blocking MLL recruitment predominantly at the level of the menin-MLL interaction, it can inhibit androgen receptor (AR)-mediated transcription. At 40 mg/kg, MI-136 has been shown to block AR signaling, inhibiting the growth of castration-resistant tumors in mice.

MI-136 Preparation Products And Raw materials

Raw materials

Preparation Products

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MI-136 Suppliers

China 54 India 1 United States 11 Global 66
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
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4861
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Musechem
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+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
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60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
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58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
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58
Cckinase, Inc.
Tel
+1 (732)236-3202
Email
sales@cckinase.com
Country
United States
ProdList
2738
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58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
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58
TargetMol Chemicals Inc.
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Email
support@targetmol.com
Country
United States
ProdList
38632
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58
ApexBio Technology
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Fax
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sales@apexbt.com
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United States
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BOC Sciences
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16314854226
Email
info@bocsci.com
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United States
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Cayman Chemical Company
Tel
--
Fax
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Email
cayman@caymanchem.com
Country
United States
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6213
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81
Matrix Scientific
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Email
sales@matrixscientific.com
Country
United States
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1628316-74-4, MI-136Related Search:

SAR405838 (MI-773) MI-3 (Menin-MLL Inhibitor) MI-2 (Menin-MLL Inhibitor) CeftazidiMe

  • MI-136
  • MI-136;HY-19319 (MI 136; MI136);
  • HY-19319 (MI 136
  • 1H-Indole-2-carbonitrile, 5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-
  • MI136;MI 136
  • CS-2162
  • 5-[[4-[[6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-1H-indole-2-carbonitrile
  • 5-((4-((6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)methyl)-1H-in
  • PPI,MI 136,Apoptosis,inhibit,MI136,Inhibitor,CRPC,castration,cancer,resistant,MI-136,Androgen Receptor,Epigenetic Reader Domain,prostate
  • 5-((4-((6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)methyl)-1H-indole-2-carbonitrile
  • 1628316-74-4
  • C23H21F3N6S