6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile

Product Name: 6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile
CAS No.: 1207836-10-9
Chemical Name: 6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile
Synonyms: LOXO-292 intermediate;6-Bromo-4-methoxypyrazoL;Selpercatinib intermediate;o[1,5-a]pyridine-3-carbonitriL;6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonit;6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile;6-bromo-4-methoxypyrazolol[.5-alpyridine-3-carbonitrile;6-bromo-4-methoxypyrazole[1,5-a]pyridine-3-carbonitrile;6-Bromo-4-methoxypyrazolo [1,5-A] pyridine-3-acetonitrile;Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-bromo-4-methoxy-
CBNumber: CB83143962
Molecular Formula: C9H6BrN3O
Formula Weight: 252.07
MOL File: 1207836-10-9.mol

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6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile Property

Density: 1.67±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: -1.97±0.30(Predicted)
InChI: InChI=1S/C9H6BrN3O/c1-14-8-2-7(10)5-13-9(8)6(3-11)4-12-13/h2,4-5H,1H3
InChIKey: JTEWRYBKHXGXHP-UHFFFAOYSA-N
SMILES: C12=C(C#N)C=NN1C=C(Br)C=C2OC

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

AK Scientific

Product number: 0400DP
Product name: 6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile
Packaging: 5g
Price: $1275
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0621203
Product name: 6-BROMO-4-METHOXYPYRAZOLO[1,5-A]PYRIDINE-3-CARBONITRILE
Purity: 95.00%
Packaging: 5MG
Price: $502.68
Updated: 2021/12/16

Ambeed

Product number: A866632
Product name: 6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile
Purity: 95%
Packaging: 100g
Price: $920
Updated: 2021/12/16

Chemenu

Product number: CM325273
Product name: 6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile
Purity: 95+%
Packaging: 100g
Price: $1263
Updated: 2021/12/16

Crysdot

Product number: CD11373512
Product name: 6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile
Purity: 98%
Packaging: 5g
Price: $1663
Updated: 2021/12/16

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6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile Chemical Properties,Usage,Production

Uses

6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile is an organic intermediate for laboratory R&D processes.

Synthesis

The DMF 10L solution of 2,4,6-trimethylbenzenesulfonic acid 3-bromo-5-methoxypyridinamine salt 2000g (4.96mol, 1.0eq), 2-chloropropene cyanide (7.44mol, 1.5eq) was added with potassium carbonate 684g (4.96mol, 1.0eq) and stirred at 20-30°C for 8h. Then the mixtrue was heated with dropwise 1132g (7.44mol, 1.5eq) of diazabicyclo at 50-60°C for 20h. After the reaction is finished and poured into water 30 L at RT. the solution was filtered, washed with water and recrystallized in ethanol to give a pale yellow solid, 6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile (702g 56%).

6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile Suppliers

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View Lastest Price from 6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile manufacturers

hebei hongtan Biotechnology Co., Ltd

Product: 6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile 1207836-10-9
Price: US $75.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000kg
Release date: 2024-03-18

hebei hongtan Biotechnology Co., Ltd

Product: Selpercatinib intermediate 1207836-10-9
Price: US $30.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2024-03-19

Jinan Million Pharmaceutical Co., Ltd

Product: 6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile 1207836-10-9
Price: US $2.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1200KG/M
Release date: 2023-08-11

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