GTQTUABHRCWVLL-UHFFFAOYSA-N

Product Name: GTQTUABHRCWVLL-UHFFFAOYSA-N
CAS No.: 1383450-81-4
Chemical Name: GTQTUABHRCWVLL-UHFFFAOYSA-N
Synonyms: JNJ-678);Rilematovir;Rilematovir (JNJ-678);JNJ-678 (JNJ-53718678);JNJ-53718678 (JNJ53718678;Rilematovir, 10 mM in DMSO;GTQTUABHRCWVLL-UHFFFAOYSA-N;Rilematovir (Synonyms: JNJ-678;GTQTUABHRCWVLL-UHFFFAOYSA-N,JNJ-53718678;3-((5-Chloro-1-(3-(methylsulfonyl)propyl)-1H-indol-2-yl)methyl)-1-(2,2,2-trifluoroethyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one
CBNumber: CB83147021
Molecular Formula: C21H20ClF3N4O3S
Formula Weight: 500.92
MOL File: 1383450-81-4.mol

More

Less

GTQTUABHRCWVLL-UHFFFAOYSA-N Property

Boiling point:: 672.5±55.0 °C(Predicted)
Density: 1.50±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:65.0(Max Conc. mg/mL);129.76(Max Conc. mM)
form: A crystalline solid
pka: 6.39±0.20(Predicted)
color: White to off-white

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-0043622
Product name: JNJ-678
Purity: 98.22%
Packaging: 5mg
Price: $450
Updated: 2021/12/16

ChemScene

Product number: CS-0043622
Product name: JNJ-678
Purity: 98.22%
Packaging: 10mg
Price: $750
Updated: 2021/12/16

ChemScene

Product number: CS-0043622
Product name: JNJ-678
Purity: 98.22%
Packaging: 25mg
Price: $1500
Updated: 2021/12/16

ChemScene

Product number: CS-0043622
Product name: JNJ-678
Purity: 98.22%
Packaging: 50mg
Price: $2100
Updated: 2021/12/16

ChemScene

Product number: CS-0043622
Product name: JNJ-678
Purity: 98.22%
Packaging: 100mg
Price: $3300
Updated: 2021/12/16

More

Less

GTQTUABHRCWVLL-UHFFFAOYSA-N Chemical Properties,Usage,Production

Uses

Rilematovir (JNJ-678) is a novel fusion protein inhibitor. Rilematovir has the potential for respiratory syncytial virus (RSV) research.

in vivo

Oral treatment of neonatal lambs with Rilematovir, or with an equally active close analog, efficiently inhibits established acute lower respiratory tract infection in the animals, even when treatment is delayed until external signs of respiratory syncytial virus illness have become visible^[1].

References

[1] Roymans D, et al. Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor. Nat Commun. 2017 Aug 1;8(1):167. DOI:10.1038/s41467-017-00170-x

GTQTUABHRCWVLL-UHFFFAOYSA-N Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

GTQTUABHRCWVLL-UHFFFAOYSA-N Suppliers

China 44 United States 3 Global 47

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

1383450-81-4, GTQTUABHRCWVLL-UHFFFAOYSA-NRelated Search:

GTQTUABHRCWVLL-UHFFFAOYSA-N

JNJ-53718678 (JNJ53718678

JNJ-678)

3-({5-Chloro-1-[3-(methylsulfonyl)propyl]-1H-indol-2-yl}methyl)-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one

2H-Imidazo[4,5-c]pyridin-2-one, 3-[[5-chloro-1-[3-(methylsulfonyl)propyl]-1H-indol-2-yl]methyl]-1,3-dihydro-1-(2,2,2-trifluoroethyl)-

JNJ-678 (JNJ-53718678)

GTQTUABHRCWVLL-UHFFFAOYSA-N,JNJ-53718678

Rilematovir (Synonyms: JNJ-678

3-((5-Chloro-1-(3-(methylsulfonyl)propyl)-1H-indol-2-yl)methyl)-1-(2,2,2-trifluoroethyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one

Rilematovir

Rilematovir (JNJ-678)

Rilematovir, 10 mM in DMSO

1383450-81-4

C21H20ClF3N4O3S