ChemicalBook > CAS DataBase List > (R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole

(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole

Product Name
(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole
CAS No.
681490-95-9
Chemical Name
(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole
Synonyms
(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole;(R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropyl 4-Nitrobenzoate;1H-Imidazole-1-propanol, 2-chloro-β-hydroxy-β-methyl-4-nitro-, 1-(4-nitrobenzoate), (βR)-
CBNumber
CB83154144
Molecular Formula
C14H13ClN4O7
Formula Weight
384.73
MOL File
681490-95-9.mol
More
Less

(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole Property

Melting point:
122-123 °C(Solv: ethyl acetate (141-78-6); isopropyl ether (108-20-3))
Boiling point:
638.9±65.0 °C(Predicted)
Density 
1.58±0.1 g/cm3(Predicted)
solubility 
Chloroform, DCM
form 
Solid
pka
12.81±0.29(Predicted)
color 
Off-White
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
C367630
Product name
(R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropyl4-Nitrobenzoate
Packaging
50mg
Price
$525
Updated
2021/12/16
More
Less

(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole Chemical Properties,Usage,Production

Uses

(R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropyl 4-Nitrobenzoate is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis.

(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole Suppliers

Canada 1 China 6 India 1 United Kingdom 1 Global 9
Lynnchem
Tel
86-(0)29-85992781 17792393971
Email
info@lynnchem.com
Country
China
ProdList
4587
Advantage
58
Novachemistry
Tel
44-20819178-90 02081917890
Fax
(0)2080432064
Email
info@novachemistry.com
Country
United Kingdom
ProdList
4381
Advantage
58
Beijing xinyanhui pharmaceutical research and development co., LTD
Tel
13969155946
Email
1461866103@qq.com
Country
China
ProdList
16111
Advantage
58
Suzhou Meishi Biotechnology Co., Ltd.
Tel
1173954148q
Email
meishipharma@126.com
Country
China
ProdList
20033
Advantage
58
Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd
Tel
18162595016; 18162595016
Email
3287908757@qq.com
Country
China
ProdList
9122
Advantage
58
Tel
4008-099-669
Email
23419001name@qq.com
Country
CHINA
ProdList
73043
Advantage
58

681490-95-9, (R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazoleRelated Search:


  • (R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole
  • (R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropyl 4-Nitrobenzoate
  • 1H-Imidazole-1-propanol, 2-chloro-β-hydroxy-β-methyl-4-nitro-, 1-(4-nitrobenzoate), (βR)-
  • 681490-95-9
  • C14H13ClN4O7