Tegoprazan

Drug Approval Medical efficacy

Product Name: Tegoprazan
CAS No.: 942195-55-3
Chemical Name: Tegoprazan
Synonyms: 7-[[(4S)-5,7-difluoro-3,4-dihydro-2H-chromen-4-yl]oxy]-N,N,2-trimethyl-3H-benzimidazole-5-carboxamide;1H-Benzimidazole-5-carboxamide, 7-[[(4S)-5,7-difluoro-3,4-dihydro-2H-1-benzopyran-4-yl]oxy]-N,N,2-trimethyl-;RQ-4;CJ 12420;Tigorasan;Tegoprazan;RQ-00000004;Tegopmsam Al;Tegoprazan API;Tegoprazan (B)
CBNumber: CB83159891
Molecular Formula: C20H19F2N3O3
Formula Weight: 387.38
MOL File: 942195-55-3.mol

More

Less

Tegoprazan Property

Boiling point:: 596.5±50.0 °C(Predicted)
Density: 1.371±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: soluble
form: A solid
pka: 9.73±0.30(Predicted)
color: Off-white to light yellow
InChI: InChI=1S/C20H19F2N3O3/c1-10-23-14-6-11(20(26)25(2)3)7-17(19(14)24-10)28-15-4-5-27-16-9-12(21)8-13(22)18(15)16/h6-9,15H,4-5H2,1-3H3,(H,23,24)/t15-/m0/s1
InChIKey: CLIQCDHNPDMGSL-HNNXBMFYSA-N
SMILES: C1(C)NC2=C(O[C@@H]3C4=C(F)C=C(F)C=C4OCC3)C=C(C(N(C)C)=O)C=C2N=1

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning

More

Less

N-Bromosuccinimide Price

TRC

Product number: T145030
Product name: Tegoprazan
Packaging: 0.5mg
Price: $235
Updated: 2021/12/16

TRC

Product number: T145030
Product name: Tegoprazan
Packaging: 5mg
Price: $2365
Updated: 2021/12/16

ChemScene

Product number: CS-0014702
Product name: Tegoprazan
Purity: 98.85%
Packaging: 50mg
Price: $1450
Updated: 2021/12/16

ChemScene

Product number: CS-0014702
Product name: Tegoprazan
Purity: 98.85%
Packaging: 100mg
Price: $2250
Updated: 2021/12/16

ChemScene

Product number: CS-0014702
Product name: Tegoprazan
Purity: 98.85%
Packaging: 5mg
Price: $300
Updated: 2021/12/16

More

Less

Tegoprazan Chemical Properties,Usage,Production

Drug Approval

Tegoprazan was approved by the Ministry of Food and Drug Safety (MFDS) for marketing in July 2018 for the treatment of gastroesophageal reflux disease and erosive esophagitis. Tegoprazan was originally developed by Pfizer. In 2008, it was licensed to RaQualiaPharma (separated from Pfizer) for joint development. In 2014, Tegoprazan was licensed to CJHealthCare by RaQualiaPharma. Finally, CJHealthCare was successfully developed and marketed in Korea. The drug was first marketed in South Korea.

Medical efficacy

Tegoprazan is medicine for treating gastroesophageal reflux disease and erosive esophagitis. Proton pump hydrogen ion/potassium ion exchange ATPase is the main pharmacological target for the treatment of gastric acid-related diseases. Potassium-competitive acid blocker (P-CAB) can inhibit gastric acid secretion by competitively binding to K+ with H+/K+-ATPase. Research finds that Tegoprazan is such a potassium-competitive acid blocker and is considered to be the most advanced drug for treating gastroesophageal reflux disease, because proton pump inhibitors are the most commonly used drugs for treating gastroesophageal reflux disease.

Uses

Tegoprazan is used for remedying and treating nocturnal acid breakthrough symptoms, such as GERD, ulcer, Barrett''s esophagus, and heartburn.

Tegoprazan Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Tegoprazan Suppliers

China 133 India 5 United States 4 Global 142

Kaifeng Mingren Pharmaceutical Co.,LTD

Tel: 0371-65741762
Fax: QQ：2860768577
Email: sales@hasunny.com
Country: China
ProdList: 2380
Advantage: 58

Joyochem Co.,Ltd

Tel: 531-82687558 13290333633
Email: sales@joyochem.com
Country: China
ProdList: 19
Advantage: 58

Hubei wei shi reagent group ltd., company

Tel: 027-02759101766 13125137661
Email: 2853877621@qq.com
Country: China
ProdList: 5799
Advantage: 58

Anhui Lianchuang Biological Medicine Co.,Ltd

Tel: 0551-68779238 18056025720
Email: sales3@lcywhx.com
Country: China
ProdList: 159
Advantage: 57

Beijing Zhongshuo Pharmaceutical Technology Development Co., Ltd

Tel: 010-53679529 13801208576
Fax: 010-64215766
Email: sales.2@chinazhongshuo.com
Country: China
ProdList: 99
Advantage: 65

Shanghai Synmedia Chemical Co., Ltd.

Tel: 021-38681880 13817889927
Fax: 0213390-8196
Email: sales@synmedia-chem.com
Country: China
ProdList: 249
Advantage: 58

Hunan Furui Biopharma Technology Co., Ltd.

Tel: 15902102743
Fax: 0731-57805668
Email: shelley@furuipharma.com
Country: China
ProdList: 452
Advantage: 55

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3239
Advantage: 55

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18070
Advantage: 56

More

Less

View Lastest Price from Tegoprazan manufacturers

HangZhou RunYan Pharma Technology Co.,LTD.

Product: Tegoprazan 942195-55-3
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 10000
Release date: 2024-09-04

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Tegoprazan 942195-55-3
Price: US $45.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000kg/Week
Release date: 2024-05-10

BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.

Product: Tegoprazan 942195-55-3
Price: US $0.00/g
Min. Order: 1g
Purity: More Than 99%
Supply Ability: 100kg/Month
Release date: 2024-07-23

942195-55-3, TegoprazanRelated Search:

7-[[(4S)-5,7-difluoro-3,4-dihydro-2H-chromen-4-yl]oxy]-N,N,2-trimethyl-3H-benzimidazole-5-carboxamide

CJ 12420

RQ-00000004

RQ-4

1H-Benzimidazole-5-carboxamide, 7-[[(4S)-5,7-difluoro-3,4-dihydro-2H-1-benzopyran-4-yl]oxy]-N,N,2-trimethyl-

7-[[(4S)-5,7-difluoro-3,4-dihydro-2H-1-benzopyran-4-yl]oxy]-N,N,2-trimethyl-1H-benzimidazole-5-carboxamide

Tegoprazan Emixustat HCL Hydrochloride

Tegoprazan

(S)-4-((5,7-difluorochroman-4-yl)oxy)-N,N,2-trimethyl-1H-benzo[d]imidazole-6-carboxamide

pentagastrin,Proton Pump,acid,Tegoprazan,gastric,secretion,inhibit,Inhibitor

Tegoprazan API

Tegoprazan (B)

(S)-7-((5,7-Difluorochroman-4-yl)oxy)-N,N,2-trimethyl-1H-benzo[d]imidazole-5-carboxamide

Tegopmsam Al

Tigorasan

942195-55-3

C20H19F2N3O3

Tegoprazan

API