Drug Approval Medical efficacy
ChemicalBook > CAS DataBase List > Tegoprazan

Tegoprazan

Drug Approval Medical efficacy
Product Name
Tegoprazan
CAS No.
942195-55-3
Chemical Name
Tegoprazan
Synonyms
7-[[(4S)-5,7-difluoro-3,4-dihydro-2H-chromen-4-yl]oxy]-N,N,2-trimethyl-3H-benzimidazole-5-carboxamide;1H-Benzimidazole-5-carboxamide, 7-[[(4S)-5,7-difluoro-3,4-dihydro-2H-1-benzopyran-4-yl]oxy]-N,N,2-trimethyl-;RQ-4;CJ 12420;Tegoprazan;RQ-00000004;Tegoprazan API;Tegoprazan (B);Tegoprazan Emixustat HCL Hydrochloride;pentagastrin,Proton Pump,acid,Tegoprazan,gastric,secretion,inhibit,Inhibitor
CBNumber
CB83159891
Molecular Formula
C20H19F2N3O3
Formula Weight
387.38
MOL File
942195-55-3.mol
More
Less

Tegoprazan Property

Boiling point:
596.5±50.0 °C(Predicted)
Density 
1.371±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: soluble
form 
A solid
pka
9.73±0.30(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
More
Less

N-Bromosuccinimide Price

TRC
Product number
T145030
Product name
Tegoprazan
Packaging
0.5mg
Price
$235
Updated
2021/12/16
TRC
Product number
T145030
Product name
Tegoprazan
Packaging
5mg
Price
$2365
Updated
2021/12/16
ChemScene
Product number
CS-0014702
Product name
Tegoprazan
Purity
98.85%
Packaging
50mg
Price
$1450
Updated
2021/12/16
ChemScene
Product number
CS-0014702
Product name
Tegoprazan
Purity
98.85%
Packaging
100mg
Price
$2250
Updated
2021/12/16
ChemScene
Product number
CS-0014702
Product name
Tegoprazan
Purity
98.85%
Packaging
5mg
Price
$300
Updated
2021/12/16
More
Less

Tegoprazan Chemical Properties,Usage,Production

Drug Approval

Tegoprazan was approved by the Ministry of Food and Drug Safety (MFDS) for marketing in July 2018 for the treatment of gastroesophageal reflux disease and erosive esophagitis. Tegoprazan was originally developed by Pfizer. In 2008, it was licensed to RaQualiaPharma (separated from Pfizer) for joint development. In 2014, Tegoprazan was licensed to CJHealthCare by RaQualiaPharma. Finally, CJHealthCare was successfully developed and marketed in Korea. The drug was first marketed in South Korea.

Medical efficacy

Tegoprazan is medicine for treating gastroesophageal reflux disease and erosive esophagitis. Proton pump hydrogen ion/potassium ion exchange ATPase is the main pharmacological target for the treatment of gastric acid-related diseases. Potassium-competitive acid blocker (P-CAB) can inhibit gastric acid secretion by competitively binding to K+ with H+/K+-ATPase. Research finds that Tegoprazan is such a potassium-competitive acid blocker and is considered to be the most advanced drug for treating gastroesophageal reflux disease, because proton pump inhibitors are the most commonly used drugs for treating gastroesophageal reflux disease.

Uses

Tegoprazan is used for remedying and treating nocturnal acid breakthrough symptoms, such as GERD, ulcer, Barrett''s esophagus, and heartburn.

Tegoprazan Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Tegoprazan Suppliers

Kaifeng Mingren Pharmaceutical Co.,LTD
Tel
0371-65741762
Fax
QQ:2860768577
Email
sales@hasunny.com
Country
China
ProdList
2380
Advantage
58
Hunan Furui Biopharma Technology Co., Ltd.
Tel
15902102743
Fax
0731-57805668
Email
shelley@furuipharma.com
Country
China
ProdList
435
Advantage
55
Joyochem Co.,Ltd
Tel
531-82687558 13290333633
Email
sales@joyochem.com
Country
China
ProdList
19
Advantage
58
Anhui Lianchuang Biological Medicine Co.,Ltd
Tel
0551-68779238 18056025720
Email
sales3@lcywhx.com
Country
China
ProdList
168
Advantage
57
Shanghai Synmedia Chemical Co., Ltd.
Tel
021-38681880 13817889927
Fax
0213390-8196
Email
sales@synmedia-chem.com
Country
China
ProdList
249
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17982
Advantage
56
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7892
Advantage
56
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4121
Advantage
55
ATK CHEMICAL COMPANY LIMITED
Tel
3429815786 13301662590
Fax
+86-21-51619052
Email
sales@atkchemical.com
Country
China
ProdList
10006
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9709
Advantage
58
More
Less

View Lastest Price from Tegoprazan manufacturers

airuikechemical co., ltd.
Product
Tegoprazan 942195-55-3
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-04-08
Zibo Wei Bin Import & Export Trade Co. Ltd.
Product
Tegoprazan 942195-55-3
Price
US $100.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1t
Release date
2023-07-11
Zhengzhou Anbu Chem Co.,Ltd
Product
Tegoprazan 942195-55-3
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1000KGS
Release date
2023-06-19

942195-55-3, TegoprazanRelated Search:


  • 7-[[(4S)-5,7-difluoro-3,4-dihydro-2H-chromen-4-yl]oxy]-N,N,2-trimethyl-3H-benzimidazole-5-carboxamide
  • CJ 12420
  • RQ-00000004
  • RQ-4
  • 1H-Benzimidazole-5-carboxamide, 7-[[(4S)-5,7-difluoro-3,4-dihydro-2H-1-benzopyran-4-yl]oxy]-N,N,2-trimethyl-
  • 7-[[(4S)-5,7-difluoro-3,4-dihydro-2H-1-benzopyran-4-yl]oxy]-N,N,2-trimethyl-1H-benzimidazole-5-carboxamide
  • Tegoprazan Emixustat HCL Hydrochloride
  • Tegoprazan
  • (S)-4-((5,7-difluorochroman-4-yl)oxy)-N,N,2-trimethyl-1H-benzo[d]imidazole-6-carboxamide
  • pentagastrin,Proton Pump,acid,Tegoprazan,gastric,secretion,inhibit,Inhibitor
  • Tegoprazan API
  • Tegoprazan (B)
  • 942195-55-3
  • C20H19F2N3O3
  • Tegoprazan
  • API