Glecaprevir
Approval- Product Name
- Glecaprevir
- CAS No.
- 1365970-03-1
- Chemical Name
- Glecaprevir
- Synonyms
- ABT-493;CS-2616;Glecaprevir;Glecaprevir INN;Glecaprevir API;Glecaprevir 13CD3;Glecaprevir(ABT-493);ABT-493(Glecaprevir);ABT-493;ABT 493;ABT493;GLECAPREVIR;(1R,2R)-N-[[[(1R,2R)-2-[[4,4-Difluoro-4-(3-hydroxy-2-quinoxalinyl)-2-buten-1-yl]oxy]cyclopentyl]oxy]carbonyl]-3-methyl-L-valyl-(4R)-4-hydroxy-L-prolyl-1-amino-2-(difluoromethyl)-N-[(1-methylcyclopropyl)sulfonyl]cyclopropanecarboxamide cyclic (1→2)-ether
- CBNumber
- CB83159912
- Molecular Formula
- C38H46F4N6O9S
- Formula Weight
- 838.87
- MOL File
- 1365970-03-1.mol
Glecaprevir Property
- Melting point:
- >186°C (dec.)
- Density
- 1.46±0.1 g/cm3(Predicted)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 4.46±0.40(Predicted)
- form
- Solid
- color
- White to Off-White
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 27934
- Product name
- Glecaprevir
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
- Product number
- 27934
- Product name
- Glecaprevir
- Packaging
- 25mg
- Price
- $745
- Updated
- 2024/03/01
- Product number
- 27934
- Product name
- Glecaprevir
- Packaging
- 5mg
- Price
- $193
- Updated
- 2024/03/01
- Product number
- 27934
- Product name
- Glecaprevir
- Packaging
- 10mg
- Price
- $341
- Updated
- 2024/03/01
- Product number
- CS-8098
- Product name
- Glecaprevir
- Purity
- 99.93%
- Packaging
- 5mg
- Price
- $420
- Updated
- 2021/12/16
Glecaprevir Chemical Properties,Usage,Production
Approval
On 19 December 2016, AbbVie submitted a new drug application to the U.S. Food and Drug Administration for the glecaprevir/pibrentasvir (trade name Mavyret) regimen for the treatment of all major genotypes of chronic hepatitis C. On 3 August 2017 the FDA approved the combination for hepatitis C treatment. In Europe, it was approved on 17 August 2017 for the same indication, under the trade name Maviret.
Uses
Glecaprevir is an antiviral drug used in the treatment of patients with hepatitis C virus (HCV) genotype 1-6, of special interest for the treatment of patients with chronic kidney disease also suffering from HCV.
Uses
Glecaprevir (INN) is a hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease inhibitor that was identified jointly by AbbVie and Enanta Pharmaceuticals. It is being developed as a treatment of chronic hepatitis C infection in co-formulation with an HCV NS5A inhibitor pibrentasvir. Together they demonstrated potent antiviral activity against major HCV genotypes and high barriers to resistance in vitro.
Side effects
The most common adverse effects, observed in at least 10% of phase 3 trial participants, were headache and fatigue.
Glecaprevir Preparation Products And Raw materials
Raw materials
Preparation Products
Glecaprevir Suppliers
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View Lastest Price from Glecaprevir manufacturers
- Product
- Glecaprevir 1365970-03-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-02