ChemicalBook > CAS DataBase List > MLi-2
MLi-2
- Product Name
- MLi-2
- CAS No.
- 1627091-47-7
- Chemical Name
- MLi-2
- Synonyms
- MLi-2;MLi-2, LRRK2 inhibitor;MLi-2, LRRK2 inhibitor (DMSO solution);MLi2,MLi-2,Inhibitor,Leucine-rich repeat kinase 2,inhibit,disease,orally,LRRK2,Parkinson’s,MLi 2;rel-(2S,6R)-2,6-Dimethyl-4-(6-(5-(1-methylcyclopropoxy)-1H-indazol-3-yl)pyrimidin-4-yl)morpholine;rel-3-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-pyrimidyl]-5-[(1-methylcyclopropyl)oxy]-1H-indazole;1H-Indazole, 3-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-pyrimidinyl]-5-[(1-methylcyclopropyl)oxy]-, rel-
- CBNumber
- CB83167643
- Molecular Formula
- C21H25N5O2
- Formula Weight
- 379.46
- MOL File
- 1627091-47-7.mol
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MLi-2 Property
- Boiling point:
- 625.8±55.0 °C(Predicted)
- Density
- 1.257±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 15 mg/ml
- form
- A crystalline solid
- pka
- 11.24±0.40(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
Tocris
- Product number
- 5756
- Product name
- MLi-2
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $293
- Updated
- 2021/12/16
Tocris
- Product number
- 5756
- Product name
- MLi-2
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $1230
- Updated
- 2021/12/16
TRC
- Product number
- M425473
- Product name
- MLi-2
- Packaging
- 0.5mg
- Price
- $235
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FD157083
- Product name
- MLi-2
- Packaging
- 10mg
- Price
- $175
- Updated
- 2021/12/16
AK Scientific
- Product number
- 1437DY
- Product name
- cis-2,6-Dimethyl-4-(6-(5-(1-methylcyclopropoxy)-1H-indazol-3-yl)pyrimidin-4-yl)morpholine
- Packaging
- 10mg
- Price
- $320
- Updated
- 2021/12/16
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MLi-2 Chemical Properties,Usage,Production
Uses
MLi-2 is a leucine-rich repeat kinase 2 (LRRK2) inhibitor and may be used in the treatment and prevention of Parkinson’s disease as its a precursor to the illness.
Definition
ChEBI: MLI-2 is a member of the class of indazoles that is 1H-indazole that is substituted at position 3 by a 6-(cis-2,6-dimethylmorpholin-4-yl)pyrimidin-4-yl group and at position 5 by a (1-methylcyclopropoxy)group. It is an inhibitor of leucine-rich repeat kinase 2 (LRRK2). It has a role as an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. It is a member of indazoles, a member of pyrimidines, a member of morpholines, a member of cyclopropanes, an aromatic ether and a tertiary amino compound.
storage
Store at -20°C
MLi-2 Preparation Products And Raw materials
Raw materials
Preparation Products
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