N-BOC-4-CARBOXYMETHOXY-PIPERIDINE

Product Name: N-BOC-4-CARBOXYMETHOXY-PIPERIDINE
CAS No.: 161948-70-5
Chemical Name: N-BOC-4-CARBOXYMETHOXY-PIPERIDINE
Synonyms: ST5313750;ASN 07731208;ASINEX-REAG BAS 07731208;N-BOC-4-CARBOXYMETHOXY-PIPERIDINE;1-Boc-4-Carboxymethoxy-Piperidine;(1-Boc-4-piperidinyloxy)acetic acid;2-[(1-Boc-4-piperidyl)oxy]acetic Acid;(1-Boc-4-piperidinyloxy)aceticacid,95%;(1-Boc-4-piperidinyloxy)acetic acid, 95%;(1-Boc-4-piperidinyloxy)acetic acid - [C0836]
CBNumber: CB8317696
Molecular Formula: C12H21NO5
Formula Weight: 259.3
MOL File: 161948-70-5.mol

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N-BOC-4-CARBOXYMETHOXY-PIPERIDINE Property

Melting point:: 105-107℃
Boiling point:: 406.7±35.0 °C(Predicted)
Density: 1.17±0.1 g/cm3(Predicted)
storage temp.: Store at room temperature
pka: 3.42±0.10(Predicted)
Appearance: White to off-white Solid
InChI: InChI=1S/C12H21NO5/c1-12(2,3)18-11(16)13-6-4-9(5-7-13)17-8-10(14)15/h9H,4-8H2,1-3H3,(H,14,15)
InChIKey: YHUAHIMRWSVXCN-UHFFFAOYSA-N
SMILES: N1(C(OC(C)(C)C)=O)CCC(OCC(O)=O)CC1

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Safety

Hazard Codes: Xi,T
Risk Statements: 25
Safety Statements: 45
HazardClass: IRRITANT
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Matrix Scientific

Product number: 018889
Product name: 4-Carboxymethoxy-piperidine-1-carboxylic acidtert-butyl ester
Packaging: 1g
Price: $186
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB13074
Product name: {[1-(tert-Butoxycarbonyl)piperidin-4-yl]oxy}acetic acid
Packaging: 500mg
Price: $200
Updated: 2021/12/16

Apolloscientific

Product number: OR962583
Product name: (1-Boc-4-piperidinyloxy)aceticacid
Purity: 97%
Packaging: 500mg
Price: $207
Updated: 2021/12/16

Apolloscientific

Product number: OR962583
Product name: (1-Boc-4-piperidinyloxy)aceticacid
Purity: 97%
Packaging: 1g
Price: $332
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB13074
Product name: {[1-(tert-Butoxycarbonyl)piperidin-4-yl]oxy}acetic acid
Packaging: 1g
Price: $340
Updated: 2021/12/16

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N-BOC-4-CARBOXYMETHOXY-PIPERIDINE Chemical Properties,Usage,Production

Synthesis

189889-45-0

161948-70-5

GENERAL STEPS: To a 100 mL round bottom flask was added tert-butyl 4-(2-ethoxy-2-oxoethoxy)piperidine-1-carboxylate (5.00 g, 17.4 mmol), sodium hydroxide (3.00 g, 75.0 mmol), water (20 mL), and ethanol (20 mL). The reaction mixture was stirred at room temperature for 48 hours. Upon completion of the reaction, the mixture was concentrated under reduced pressure to remove the solvent. The pH of the residue was adjusted with 3 mol/L hydrochloric acid solution to 2. Subsequently, the aqueous phase was extracted with ethyl acetate (2 x 20 mL), and the organic layers were combined and concentrated under reduced pressure to afford 4.00 g (89% yield) of 2-([1-[(tert-butoxy)carbonyl]piperidin-4-yl]oxy)acetic acid as an oil. Thin layer chromatography (TLC) analytical conditions: dichloromethane/methanol = 5/1, Rf = 0.4.

References

[1] Patent: WO2017/89390, 2017, A1. Location in patent: Page/Page column 97; 98
[2] European Journal of Medicinal Chemistry, 1999, vol. 34, # 5, p. 363 - 380
[3] Patent: WO2014/151958, 2014, A1. Location in patent: Paragraph 00290

N-BOC-4-CARBOXYMETHOXY-PIPERIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-BOC-4-CARBOXYMETHOXY-PIPERIDINE Suppliers

Canada 1 China 52 France 1 Germany 1 India 2 Russia 1 United Kingdom 2 United States 13 Global 73

Hefei Mokai Pharmaceutical Technology Co., Ltd

Tel: 18130062233
Email: 3362556465@qq.com
Country: China
ProdList: 8100
Advantage: 58

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

NovoChemy Ltd.

Tel: 021-31261262/ 49 (0)17662837245
Fax: (0)21-33250524
Email: sales@novochemy.com
Country: Germany
ProdList: 6328
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9874
Advantage: 55

Chengdu Firster Pharmaceutical Co., Ltd.

Tel: 028-87078428 028-87074958
Fax: 8772-8116
Email: chengzhenyong@cdfirster.com
Country: China
ProdList: 2598
Advantage: 60

Shanghai AQBioPharma Co., Ltd.

Tel: 13661411401
Fax: 51370935-8011
Email: yinglv.que@aqbiopharma.com.cn
Country: China
ProdList: 2930
Advantage: 58

Shanghai Xingui Biotechnology Co., Ltd.

Tel: 15121041756
Email: xingui2022@126.com
Country: China
ProdList: 9976
Advantage: 58

SanoChem (Chengdu) Tech. Co., Ltd.

Tel: 28-87999436 02887999436
Fax: QQ:2746983436
Email: sales@sano-chem.com
Country: China
ProdList: 3795
Advantage: 55

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View Lastest Price from N-BOC-4-CARBOXYMETHOXY-PIPERIDINE manufacturers

Career Henan Chemical Co

Product: N-BOC-4-CARBOXYMETHOXY-PIPERIDINE 161948-70-5
Price: US $6.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg, 5kg, 50kg
Release date: 2020-01-09

161948-70-5, N-BOC-4-CARBOXYMETHOXY-PIPERIDINERelated Search:

N-BOC-3-CARBOXYMETHOXY-PIPERIDINE 1-Boc- 4-(2-(Benzyloxy)-2-Oxoethoxy)Piperidine 1-Boc-3-(2-tert-butoxy-2-oxoethoxy)piperidine 1-Boc- 4-(2-Methoxy-2-Oxoethoxy)Piperidine 1-Boc-3-(2-(Benzyloxy)-2-Oxoethoxy)Piperidine 1-Boc-3-Carboxymethoxy-Piperidine N-BOC-4-CARBOXYMETHOXY-PIPERIDINE 1-Boc-4-methoxypiperidine 1-BOC-4-ETHOXYCARBONYLMETHOXYPIPERIDINE (PIPERIDIN-4-YLOXY)-ACETIC ACID Isopropyl 4-hydroxypiperidine-1-carboxylate Ethyl 4-hydroxypiperidine-1-carboxylate BENZYL-4-[N-BOC-PIPERIDINOXY] ACETATE 4-METHOXYCARBONYLMETHOXY-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER N-BOC-4-Hydroxypiperidine

ASINEX-REAG BAS 07731208

1-Boc-4-Carboxymethoxy-Piperidine

N-BOC-4-CARBOXYMETHOXY-PIPERIDINE

4-CARBOXYMETHOXY-PIPERIDINE-1-CARBOXYLIC ACIDTERT-BUTYL ESTER

2-[(1-tert-Butoxycarbonyl-4-piperidyl)oxy]acetic acid

(1-Boc-4-piperidinyloxy)acetic acid, 95%

{[1-(tert-butoxycarbonyl)piperidin-4-yl]oxy}acetic acid

2-[[1-(tert-butoxy-oxomethyl)-4-piperidinyl]oxy]acetic acid

2-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]oxyacetic acid

2-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]oxyethanoic acid

ASN 07731208

ST5313750

2-[[1-[(2-methylpropan-2-yl)oxy-oxomethyl]-4-piperidinyl]oxy]acetate

1-Piperidinecarboxylic acid, 4-(carboxymethoxy)-, 1-(1,1-dimethylethyl) ester

(1-Boc-4-piperidinyloxy)aceticacid,95%

2-[(1-Boc-4-piperidyl)oxy]acetic Acid

(1-Boc-4-piperidinyloxy)acetic acid - [C0836]

(1-Boc-4-piperidinyloxy)acetic acid

161948-70-5

pharmacetical