ChemicalBook > CAS DataBase List > N-BOC-4-Hydroxypiperidine

N-BOC-4-Hydroxypiperidine

Product Name
N-BOC-4-Hydroxypiperidine
CAS No.
109384-19-2
Chemical Name
N-BOC-4-Hydroxypiperidine
Synonyms
TERT-BUTYL 4-HYDROXYPIPERIDINE-1-CARBOXYLATE;1-BOC-4-HYDROXYPIPERIDINE;4-HYDROXY-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;N-(TERT-BUTOXYCARBONYL)-4-PIPERIDINOL;1-(TERT-BUTOXYCARBONYL)-4-HYDROXYPIPERIDINE;Boc-4-piperidinol;1-Bocpiperidin-4-ol;RARECHEM AH CK 0055;N-BOC-4-PIPERIDINOL;1-BOC-4-PIPERIDINOL
CBNumber
CB7382529
Molecular Formula
C10H19NO3
Formula Weight
201.26
MOL File
109384-19-2.mol
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N-BOC-4-Hydroxypiperidine Property

Melting point:
61-65 °C (lit.)
Boiling point:
292.3±33.0 °C(Predicted)
Density 
1.107±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform, Ethyl Acetate
pka
14.80±0.20(Predicted)
form 
Powder
color 
White to cream
BRN 
7202094
InChI
InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-8(12)5-7-11/h8,12H,4-7H2,1-3H3
InChIKey
PWQLFIKTGRINFF-UHFFFAOYSA-N
SMILES
N1(C(OC(C)(C)C)=O)CCC(O)CC1
CAS DataBase Reference
109384-19-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
495484
Product name
1-Boc-4-hydroxypiperidine
Purity
97%
Packaging
5g
Price
$48.94
Updated
2025/07/31
Sigma-Aldrich
Product number
495484
Product name
1-Boc-4-hydroxypiperidine
Purity
97%
Packaging
25g
Price
$103.61
Updated
2025/07/31
TCI Chemical
Product number
B2671
Product name
1-(tert-Butoxycarbonyl)-4-hydroxypiperidine
Purity
>97.0%(GC)
Packaging
5g
Price
$16
Updated
2025/07/31
TCI Chemical
Product number
B2671
Product name
1-(tert-Butoxycarbonyl)-4-hydroxypiperidine
Purity
>97.0%(GC)
Packaging
25g
Price
$40
Updated
2025/07/31
TRC
Product number
B656660
Product name
N-Boc-4-Hydroxypiperidine
Packaging
100g
Price
$110
Updated
2021/12/16
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N-BOC-4-Hydroxypiperidine Chemical Properties,Usage,Production

Chemical Properties

White to cream powder

Uses

Used in a synthesis of N-heterocyclic alkyl ethers via the Mitsunobu reaction.

Uses

N-Boc-4-hydroxypiperidine is a 4-hydroxypyridine with a boc protecting group used in the preparation of neurologically active agents and other pharmaceutical compounds.

Preparation

A mixture of 4-hydroxypiperidine (10.0 g, 98. 9 mmol), aqueous sodiumhydrogen carbonate (150 mL, 1 M), DI-FERT-BUTYL dicarbonate (21. 6 g, 98.9 mmol) and dichloromethane was stirred for 15 h. The phases were separated and the product (N-BOC-4-Hydroxypiperidine) was isolated as an oil in quantitative yield (19.9 g).

N-BOC-4-Hydroxypiperidine Preparation Products And Raw materials

Raw materials

Preparation Products

4-Amino-1-Boc-piperidine
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N-BOC-4-Hydroxypiperidine Suppliers

Americas 1 Belgium 2 Canada 3 China 308 Europe 3 France 4 Germany 10 India 48 Japan 3 Russia 1 Switzerland 3 The Netherlands 1 United Kingdom 18 United States 74 Global 479
Fuxin Kaituo Fine Chemical Technology Co., Ltd
Tel
15714082442
Email
3757845877@qq.com
Country
China
ProdList
346
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58
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2208
Advantage
55
Shanghai Tuolei Chemical Reagents Co., Ltd.
Tel
86-021-50318510
Fax
021-58650104
Country
China
ProdList
69
Advantage
55
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
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View Lastest Price from N-BOC-4-Hydroxypiperidine manufacturers

Shandong Xuhuang New material CoLTD
Product
N-boc-4-hydroxypiperidine 109384-19-2
Price
US $100.00-50.00/kg
Min. Order
1kg
Purity
99.99%
Supply Ability
500
Release date
2025-02-19
Shaanxi Dideu New Materials Co. Ltd
Product
N-BOC-4-Hydroxypiperidine 109384-19-2
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-02-27
Anhui Zhongda Biotechnology Co., Ltd
Product
N-BOC-4-Hydroxypiperidine 109384-19-2
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100tons
Release date
2023-10-24

109384-19-2, N-BOC-4-HydroxypiperidineRelated Search:

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  • Boc-4-piperidinol
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  • Pozitinib intermediate 6
  • 4-Hydroxy-piperidin-1-carboxylic acid tert-butyl ester