ChemicalBook > CAS DataBase List > N-BOC-4-Hydroxypiperidine

N-BOC-4-Hydroxypiperidine

Product Name
N-BOC-4-Hydroxypiperidine
CAS No.
109384-19-2
Chemical Name
N-BOC-4-Hydroxypiperidine
Synonyms
TERT-BUTYL 4-HYDROXYPIPERIDINE-1-CARBOXYLATE;1-BOC-4-HYDROXYPIPERIDINE;4-HYDROXY-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;N-(TERT-BUTOXYCARBONYL)-4-PIPERIDINOL;1-(TERT-BUTOXYCARBONYL)-4-HYDROXYPIPERIDINE;Boc-4-piperidinol;1-Bocpiperidin-4-ol;RARECHEM AH CK 0055;N-BOC-4-PIPERIDINOL;1-BOC-4-PIPERIDINOL
CBNumber
CB7382529
Molecular Formula
C10H19NO3
Formula Weight
201.26
MOL File
109384-19-2.mol
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N-BOC-4-Hydroxypiperidine Property

Melting point:
61-65 °C (lit.)
Boiling point:
292.3±33.0 °C(Predicted)
Density 
1.107±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform, Ethyl Acetate
pka
14.80±0.20(Predicted)
form 
Powder
color 
White to cream
BRN 
7202094
InChI
InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-8(12)5-7-11/h8,12H,4-7H2,1-3H3
InChIKey
PWQLFIKTGRINFF-UHFFFAOYSA-N
SMILES
N1(C(OC(C)(C)C)=O)CCC(O)CC1
CAS DataBase Reference
109384-19-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
495484
Product name
1-Boc-4-hydroxypiperidine
Purity
97%
Packaging
5g
Price
$59.6
Updated
2024/03/01
Sigma-Aldrich
Product number
495484
Product name
1-Boc-4-hydroxypiperidine
Purity
97%
Packaging
25g
Price
$126
Updated
2024/03/01
TCI Chemical
Product number
B2671
Product name
1-(tert-Butoxycarbonyl)-4-hydroxypiperidine
Purity
>97.0%(GC)
Packaging
5g
Price
$16
Updated
2024/03/01
TCI Chemical
Product number
B2671
Product name
1-(tert-Butoxycarbonyl)-4-hydroxypiperidine
Purity
>97.0%(GC)
Packaging
25g
Price
$40
Updated
2024/03/01
Alfa Aesar
Product number
L19275
Product name
1-Boc-4-hydroxypiperidine, 98%
Packaging
5g
Price
$66.6
Updated
2023/06/20
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N-BOC-4-Hydroxypiperidine Chemical Properties,Usage,Production

Chemical Properties

White to cream powder

Uses

Used in a synthesis of N-heterocyclic alkyl ethers via the Mitsunobu reaction.

Uses

N-Boc-4-hydroxypiperidine is a 4-hydroxypyridine with a boc protecting group used in the preparation of neurologically active agents and other pharmaceutical compounds.

Preparation

A mixture of 4-hydroxypiperidine (10.0 g, 98. 9 mmol), aqueous sodiumhydrogen carbonate (150 mL, 1 M), DI-FERT-BUTYL dicarbonate (21. 6 g, 98.9 mmol) and dichloromethane was stirred for 15 h. The phases were separated and the product (N-BOC-4-Hydroxypiperidine) was isolated as an oil in quantitative yield (19.9 g).

N-BOC-4-Hydroxypiperidine Preparation Products And Raw materials

Raw materials

Preparation Products

4-Amino-1-Boc-piperidine
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N-BOC-4-Hydroxypiperidine Suppliers

Americas 1 Belgium 2 Canada 3 China 398 Europe 3 France 4 Germany 10 India 50 Japan 3 Russia 1 Switzerland 3 The Netherlands 1 United Kingdom 18 United States 75 Global 572
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View Lastest Price from N-BOC-4-Hydroxypiperidine manufacturers

Hebei Dangtong Import and export Co LTD
Product
N-BOC-4-Hydroxypiperidine 109384-19-2
Price
US $107.00-95.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2023-09-15
Shanghai Longyu Biotechnology Co., Ltd.
Product
N-BOC-4-hydroxypiperidine 109384-19-2
Price
US $1.00/kg
Min. Order
1kg
Purity
99.99
Supply Ability
200tons
Release date
2024-11-20
Shaanxi Dideu Medichem Co. Ltd
Product
N-BOC-4-Hydroxypiperidine 109384-19-2
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
99%
Supply Ability
2000tons
Release date
2019-12-31

109384-19-2, N-BOC-4-HydroxypiperidineRelated Search:

2,2,6,6-Tetramethyl-4-piperidinol Haloperidol N-Carbobenzyloxyglycine tert-Butyl peroxyacetate Triacetonediamine tert-Butyl acetate tert-Butanol 4-Cyanophenol DROPERIDOL 1-Boc-4-cyanopiperidine N-Boc-4-piperidinemethanol tert-Butyl 4-methylenepiperidine-1-carboxylate 1-Boc-3-piperidone Diphenoxylate 4-Hydroxypiperidine Carbonyl iron powder (2R,4S)-N-BOC-4-HYDROXYPIPERIDINE-2-CARBOXYLIC ACID METHYL ESTER 1-Boc-4-methanesulfonyloxypiperidine

  • 1-Boc-4-piperidinol, tert-Butyl 4-hydroxy-1-piperidinecarboxylate
  • N-BOC-4-Hydroxypiperidine,97%
  • 1-Boc-4-hydroxypiperidine ,98%
  • N-Boc-4hydropiperidine
  • 1-(tert-Butoxycarbonyl)-4-hydroxypiperidine, tert-Butyl 4-hydroxypiperidine-1-carboxylate
  • N-Boc-4-hydroxy-1-piperidine
  • tert-butyl 4-hydroxypiperidin-1-carboxylate
  • 1-Boc -4-hydroxypeiperidine
  • 4-Hydroxy-1-(tert-butoxycarbonyl)piperidine
  • N-BOC-4-Hydroxypiperidine, 97% 25GR
  • N-BOC-4-Hydroxypiperidine, 97% 5GR
  • tert-butyl 4-hydro×ypiperidine-1-carbo×ylate
  • N-BOC-4-Hydroxypiper
  • 1-Boc-4-hydroxypiperidine 1-Boc-4-piperidinol
  • 1-(tert-Butyloxycarbonyl)-4-piperidinol
  • 1-Bocpiperidin-4-ol
  • N - bok - 4 - hydroxy piperidine
  • N-BOC-4-Hydroxypiperidine N-(tert-Butoxycarbonyl)-4-hydroxypiperidine
  • t-Butyl 4-hydroxypiperidine-1-carboxylate
  • Boc-(4-hydroxy)piperidine≥ 99% (GC)
  • RARECHEM AH CK 0055
  • TERT-BUTYL 4-HYDROXYPIPERIDINE-1-CARBOXYLATE
  • TERT-BUTYL 4-HYDROXY-1-PIPERIDINECARBOXYLATE
  • N-(TERT-BUTOXYCARBONYL)-4-HYDROXYPIPERIDINE
  • N-(TERT-BUTOXYCARBONYL)-4-PIPERIDINOL
  • N-BOC-4-PIPERIDINOL
  • N-BOC-4-HYDROXYPIPERIDINE
  • N-BOC-4-HYDROXYLPIPERIDINE
  • 1-TERT-BUTOXYCARBONYL-4-PIPERIDINOL
  • 1-(TERT-BUTOXYCARBONYL)-4-HYDROXYPIPERIDINE
  • 1-BOC-4-PIPERIDINOL
  • 1-BOC-4-HYDROXYPIPERIDINE
  • 1-PIPERIDINECARBOXYLIC ACID, 4-HYDROXY-,1,1-DIMETHYLETHYL ESTER
  • 4-HYDROXY-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
  • BOC-(4-HYDROXY)-PIPERIDINE
  • 1-N-Boc-4-hydroxypiperidine
  • TERT-BUTYL 4-HYDROXY-1-PIPERIDINE-CARBOX
  • Crizotinib Impurity 11
  • N-BOC-4-Hydroxypiperidine/1-Boc-4-piperidinol
  • 4-Hydroxypiperidine, N-BOC protected 98+%
  • 1-BOC-4-HYDROXYLPIPERIDINE
  • 1-BOC-4-HYDROXYPIPERIDINE / 1-TERT-BUTOXYCARBONYL-4-HYDROXYPIPERIDINE
  • 1-BOC-4-HYDROXY-PIPERIDINE, 1-TERT-BUTOXYCARBONYL-4-HYDROXY-PIPERIDINE 99%
  • 1-BOC-4-HYDROXYPIPERIDINE 99%
  • 4-Hydroxypiperidine, N-BOC protected
  • N-(tert-butyloxycarbonyl)-4-piperidinol
  • (R-TERT-BUTYL 3-(HYDROXYMETHYLPYRROLIDINE-1-
  • 1-(tert-Butoxycarbonyl)-4-hydroxypiperidine &gt
  • N-Boc-4-Hydroxypiperidine,>98%
  • Ibrutinib Impurity 53
  • N-tert-Butoxycarbonyl-4-hydroxy piperidine(N-BOC-4H)
  • Ibrutinib Impurity 63
  • N-Tert.Butoxycarbonyl-4-Hydroxy piperidine (or) N-boc-4-hydroxy piperidine
  • N-BOC-4-Hydroxypiperidinex
  • Boc-4-piperidinol
  • N-BOC-4-Hydroxypiperidine 109384-19-2
  • Pozitinib intermediate 6
  • 4-Hydroxy-piperidin-1-carboxylic acid tert-butyl ester