1-Boc-3-piperidone
- Product Name
- 1-Boc-3-piperidone
- CAS No.
- 98977-36-7
- Chemical Name
- 1-Boc-3-piperidone
- Synonyms
- TERT-BUTYL 3-OXOPIPERIDINE-1-CARBOXYLATE;N-BOC-3-PIPERIDINONE;N-Boc-3-piperidone;1-BOC-piperidone;1-BOC-3-PIPERIDINONE;1-(TERT-BUTOXYCARBONYL)-3-PIPERIDONE;3-OXO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;1-Boc-3-Pipe;3-Oxopiperidine;BOC-3-PIPERIDONE
- CBNumber
- CB8428473
- Molecular Formula
- C10H17NO3
- Formula Weight
- 199.25
- MOL File
- 98977-36-7.mol
1-Boc-3-piperidone Property
- Melting point:
- 35-40 °C (lit.)
- Boiling point:
- 289.8±33.0 °C(Predicted)
- Density
- 1.099±0.06 g/cm3(Predicted)
- Flash point:
- >230 °F
- storage temp.
- 2-8°C
- pka
- -1.71±0.20(Predicted)
- form
- Liquid
- color
- Clear colorless
- Water Solubility
- It is insoluble in water.
- BRN
- 5936353
- InChI
- InChI=1S/C10H17NO3/c1-10(2,3)14-9(13)11-6-4-5-8(12)7-11/h4-7H2,1-3H3
- InChIKey
- RIFXIGDBUBXKEI-UHFFFAOYSA-N
- SMILES
- N1(C(OC(C)(C)C)=O)CCCC(=O)C1
- CAS DataBase Reference
- 98977-36-7(CAS DataBase Reference)
Safety
- Safety Statements
- 24/25
- WGK Germany
- 3
- HazardClass
- KEEP COLD
- HS Code
- 29339900
- Storage Class
- 13 - Non Combustible Solids
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 650811
- Product name
- 1-Boc-3-piperidone
- Purity
- 97%
- Packaging
- 25g
- Price
- $80.7
- Updated
- 2024/03/01
- Product number
- 650811
- Product name
- 1-Boc-3-piperidone
- Purity
- 97%
- Packaging
- 5g
- Price
- $30
- Updated
- 2023/06/20
- Product number
- B3309
- Product name
- 1-(tert-Butoxycarbonyl)-3-piperidone
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $34
- Updated
- 2026/03/19
- Product number
- B3309
- Product name
- 1-(tert-Butoxycarbonyl)-3-piperidone
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $109
- Updated
- 2026/03/19
- Product number
- 261926
- Product name
- N-Boc-3-piperidone
- Packaging
- 5g
- Price
- $333
- Updated
- 2021/12/16
1-Boc-3-piperidone Chemical Properties,Usage,Production
Chemical Properties
White to yellow low melting solid
Uses
1-Boc-3-piperidone, is used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.
Synthesis
With 179g compound 3(1-BOC-3-piperidines alcohol) drop in the 2L reaction flask, drop into pimelinketone 1300g, aluminum isopropylate 88g, methylene dichloride 400ml is warming up to 80 ℃, insulation reaction 8h, reaction finishes to be cooled to room temperature, adds 10% sodium hydroxide 200ml, stirring at normal temperature 30min, filter, the filtrate normal pressure reclaims methylene dichloride, reclaim under reduced pressure pimelinketone again, reclaim finish after, add the 300ml dichloromethane extraction three times, it is dry concentrated to merge oil reservoir, gets 1-BOC-3-piperidone crude product.
Refining: with 1-BOC-3-piperidone crude product is that 60pa, temperature are to distill under 104 ~ 105 ℃ the condition at pressure, gets 1-BOC-3-piperidone elaboration 163g, 92.9%.
References
[1] Patent: CN107573278, 2018, A. Location in patent: Paragraph 0055; 0059-0061; 0076-0077
[2] Patent: US2011/105520, 2011, A1. Location in patent: Page/Page column 36
[3] Patent: WO2009/82134, 2009, A2. Location in patent: Page/Page column 37
[4] Patent: WO2013/13308, 2013, A1. Location in patent: Paragraph 00250-00252
[5] Patent: US2003/220341, 2003, A1. Location in patent: Page/Page column 15-16
1-Boc-3-piperidone Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-Boc-3-piperidone manufacturers
- Product
- 1-Boc-3-piperidone 98977-36-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 2000tons
- Release date
- 2019-12-31
- Product
- 1-Boc-3-Piperidinone 98977-36-7
- Price
- US $10.00-8.00/kg
- Min. Order
- 1kg
- Purity
- 99.9%
- Supply Ability
- 20ton
- Release date
- 2024-06-07
- Product
- 1-Boc-3-piperidone 98977-36-7
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1 ton
- Release date
- 2023-11-02