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N-Boc-4-piperidinemethanol

Product Name
N-Boc-4-piperidinemethanol
CAS No.
123855-51-6
Chemical Name
N-Boc-4-piperidinemethanol
Synonyms
TERT-BUTYL 4-(HYDROXYMETHYL)PIPERIDINE-1-CARBOXYLATE;N-BOC-piperidine-4-methanol;BOC-PIC(4)-OL;BUTTPARK 75\50-52;N-Boc-4-piperidineMe;Boc-4-Piperidine methanol;N-BOC-piperidin-4-Methanol;N-BOC-4-PIPERIDINEMETHANOL;BOC-ISONICOT(HEXAHYDRO)-OL;1-BOC-4-PIPERIDINEMETHANOL
CBNumber
CB2100290
Molecular Formula
C11H21NO3
Formula Weight
215.29
MOL File
123855-51-6.mol
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N-Boc-4-piperidinemethanol Property

Melting point:
78-82 °C (lit.)
Boiling point:
308.0±15.0 °C(Predicted)
Density 
1.059±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Methanol
pka
14.94±0.10(Predicted)
form 
Powder
color 
White to brown
InChI
InChI=1S/C11H21NO3/c1-11(2,3)15-10(14)12-6-4-9(8-13)5-7-12/h9,13H,4-8H2,1-3H3
InChIKey
CTEDVGRUGMPBHE-UHFFFAOYSA-N
SMILES
N1(C(OC(C)(C)C)=O)CCC(CO)CC1
CAS DataBase Reference
123855-51-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Safety Statements 
24/25
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
556017
Product name
N-Boc-4-piperidinemethanol
Purity
97%
Packaging
5g
Price
$138
Updated
2023/06/20
TCI Chemical
Product number
B2364
Product name
1-(tert-Butoxycarbonyl)-4-piperidinemethanol
Purity
>98.0%(GC)
Packaging
1g
Price
$17
Updated
2025/07/31
TCI Chemical
Product number
B2364
Product name
1-(tert-Butoxycarbonyl)-4-piperidinemethanol
Purity
>98.0%(GC)
Packaging
5g
Price
$32
Updated
2025/07/31
TCI Chemical
Product number
B2364
Product name
1-(tert-Butoxycarbonyl)-4-piperidinemethanol
Purity
>98.0%(GC)
Packaging
25g
Price
$97
Updated
2025/07/31
Usbiological
Product number
261747
Product name
N-Boc-4-piperidinemethanol
Packaging
25g
Price
$319
Updated
2021/12/16
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N-Boc-4-piperidinemethanol Chemical Properties,Usage,Production

Chemical Properties

White to light brown solid

Uses

N-Boc-4-piperidinemethanol is an important piperidine derivative, which can be used in organic synthesis and pharmaceutical intermediates, It may be used to synthesize:
methyl 5-methoxy-4-(1-methylpiperidin-4-ylmethoxy)-2-nitrobenzoate
N-Boc-4-piperidinecarboxaldehyde
[1-(tert-butoxycarbonyl)piperidin-4-yl]methyl methanesulfonate
Involved in the synthesis of bradycardic agents.

Application

N-Boc-4-piperidinemethanol is a curcumin analogue that binds to the epidermal growth factor receptor (EGFR) and prevents the binding of ligands. In vitro studies have shown that it can inhibit tumor growth and induce apoptosis in cancer cells. The drug is also capable of inhibiting the proliferation of normal cells, which may be due to its ability to recruit EGFR from outside the cell membrane. This process triggers signaling events that lead to cell death.

General Description

N-Boc-4-piperidinemethanol contains a tert-butyloxycarbonyl (t-BOC)-protecting group. It can be synthesized from 4-piperidinemethanol via reaction with di-tert-butyldicarbonate.

N-Boc-4-piperidinemethanol Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Boc-4-piperidinemethanol Suppliers

Americas 1 China 366 Europe 3 France 3 Germany 4 India 26 Italy 2 Japan 3 Russia 1 Switzerland 3 The Netherlands 1 Ukraine 1 United Kingdom 18 United States 54 Global 486
Anhui Dexinjia Biopharm Co., Ltd
Tel
0531-82375892 15553111391
Email
3276840968@qq.com
Country
China
ProdList
301
Advantage
58
Shanghai Hobor Chemical Co., Ltd
Tel
021-57790084; 13918007836
Fax
021-51685238
Email
sales@hoborchem.com
Country
China
ProdList
392
Advantage
60
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
YuChen Biological Medicine
Tel
0535-7295056 15692356085
Email
sdycc1234@163.com
Country
China
ProdList
158
Advantage
58
BTC Pharmaceutical CO. Ltd
Tel
15716293042 18862996710
Fax
0513-68015394
Email
15050603958@163.com
Country
China
ProdList
694
Advantage
55
Shanghai Tuolei Chemical Reagents Co., Ltd.
Tel
86-021-50318510
Fax
021-58650104
Country
China
ProdList
69
Advantage
55
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
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View Lastest Price from N-Boc-4-piperidinemethanol manufacturers

Dideu Industries Group Limited
Product
N-Boc-4-piperidinemethanol 123855-51-6
Price
US $1.10/g
Min. Order
1g
Purity
99.0% Min
Supply Ability
100 Tons
Release date
2025-04-09
Anhui Yiao New Material Technology Co., Ltd
Product
N-(tert-Butoxycarbonyl)-4-piperidinemethanol 123855-51-6
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 tons
Release date
2023-11-02
Anhui Yiao New Material Technology Co., Ltd
Product
N-(tert-Butoxycarbonyl)-4-piperidinemethanol 123855-51-6
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 tons
Release date
2023-11-02

123855-51-6, N-Boc-4-piperidinemethanolRelated Search:

N-Boc-Piperidine-4-carboxylic acid methyl ester DROPERIDOL N-(tert-Butoxycarbonyl)-4-piperidone Haloperidol 2,2,6,6-Tetramethyl-4-piperidinol PHENCYCLIDINE-D5 HYDROCHLORIDE tert-Butyl acetate tert-Butyl peroxyacetate 4-Piperidinemethanol tert-Butanol 1-Boc-2-piperidinemethanol,1-N-Boc-2-piperidinemethanol,1-TERT-BUTOXYCARBONYL-2-PIPERIDINEMETHANOL, N-BOC-2-PIPERIDINEMETHANOL 1-TERT-BUTOXYCARBONYL-3-PIPERIDINEMETHANOL, N-BOC-3-PIPERIDINEMETHANOL,1-Boc-3-piperidinemethanol 1-Boc-4-(2-hydroxyethyl)piperidine N-BOC-4-Hydroxypiperidine tert-Butyl 4-methylenepiperidine-1-carboxylate 1-Boc-4-cyanopiperidine N-Boc-(2R,3R,4S)-dolaproine TERT-BUTYL N-(2-HYDROXYETHYL)CARBAMATE

  • 1-N-BOC-4-HYDROXYMETHYL-PIPERIDINE
  • 1-(TERT-BUTOXYCARBONYL)-4-(HYDROXYMETHYL)PIPERIDINE
  • 1-(TERT-BUTOXYCARBONYL)-4-PIPERIDINEMETHANOL
  • TERT-BUTYL 4-(HYDROXYMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE
  • TERT-BUTYL 4-(HYDROXYMETHYL)PIPERIDINE-1-CARBOXYLATE
  • N-T-BUTOXYCARBONYL-HEXAHYDROISONICOTINOL
  • N-T-BUTOXYCARBONYL-4-HYDROXYMETHYL-PIPERIDINE
  • N-T-BUTOXYCARBONYL-4-PIPECOLINOL
  • N-T-BUTOXYCARBONYL-4-PIPERIDINEMETHANOL
  • N-(TERT-BUTOXYCARBONYL)-4-(HYDROXYMETHYL)PIPERIDINE
  • N-(TERT-BUTOXYCARBONYL)-4-PIPERIDINEMETHANOL
  • 1-Boc-4-(hydroxymethyl)piperidine 1-Boc-4-piperidinemethanol 1-(tert-Butoxycarbonyl)-4-(hydroxymethyl)piperidine
  • N-Boc-4-piperidineMe
  • N-BOC-piperidine-4-methanol
  • 1-piperidinecarboxylic acid, 4-(hydroxymethyl)-, 1,1-dimet
  • N-Boc-4-piperidinemethanol ,97%
  • N-Boc-4-piperidinemethanol,N-tert-Butyloxycarbonyl-4-piperidinemethanol
  • 4-(Hydroxymethyl)piperidine, N-BOC protected 97%
  • 1-Boc-4-(hydroxymethyl)-p...
  • tert-Butyl 4-(hydroxymethyl)piperidine-1-carboxylate, 1-(tert-Butoxycarbonyl)-4-(hydroxymethyl)piperidine
  • t-Butyl 4-(hydroxymethyl)piperidine-1-carboxylate
  • tert-butyl 4-(hydroxyMethyl)piperidin-1-carboxylate
  • N-BOC-piperidin-4-Methanol
  • N-Boc-4-piperidineMethanol, 95+%
  • N - bok - 4 - piperidine Methanol
  • 1-Boc-4-piperidinemethanol Synonyms N-tert-Butyloxycarbonyl-4-piperidinemethanol
  • N-Boc-4-piperidinemethanol 97%
  • 1,1-Dimethylethyl 4-(hydroxymethyl)-1-piperidinecarboxylate
  • n-tert-butyloxycarbonyl-4-piperidinemethanol
  • N-BOC-4-HYDROXYLMETHYLENE-PIPERIDINE
  • N-BOC-4-HYDROXYMETHYLPIPERIDINE
  • N-BOC-4-PIPERIDINEMETHANOL
  • 1-N-Boc-4-piperidinemethanol
  • tert-Butyl 4-(hydroxymethyl)-1-piperidinecarboxylate
  • 1-(TERT-BUTOXYCARBONYL)-4-PYRROLIDINEMETHANOL
  • (1-Boc-Piperidin-4-yl)methanol
  • 1-TERT-BUTOXYCARBONYL-4-PIPERIDINEMETHANOL, N-BOC-4-PIPERIDINEMETHANOL
  • N-BOC-4-HYDROXYMETHYLPIPERDINE
  • N-(tert-Butoxycarbonyl)-4-(Hydroxymethyl)piperidine, 98 %
  • 1-Piperidinecarboxylic acid, 4-(hydroxymethyl)-, 1,1-dimethylethyl ester
  • 1-Boc-4-Hyroxymethyl-Piperidine
  • 4-Hydroxylmethyl-N-( tert-butylcarboxylate)piperidine
  • BUTTPARK 75\50-52
  • BOC-PIC(4)-OL
  • BOC-ISONICOT(HEXAHYDRO)-OL
  • 4-HYDROXYMETHYL-1-TERT-BUTOXYCARBONYLPIPERIDINE
  • 4-HYDROXYMETHYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
  • 4-(HYDROXYMETHYL)PIPERIDINE-N-BOC PROTECTED
  • 1-BOC-4-(HYDROXYMETHYL)PIPERIDINE
  • 1-BOC-4-PIPERIDINEMETHANOL
  • tert-Butyl 4-(hydroxymethyl)-1
  • 1-(tert-Butoxycarbonyl)-4-piperidinemethanol &gt
  • Boc-4-Piperidine methanol
  • N-Boc-4-piperidinyl alcohol
  • N-Boc 4-piperdine methanol
  • N-Boc-4-piperidinemethanol 123855-51-6
  • 4-Hydroxymethyl-piperidin-1-carboxylic acid tert-butyl ester
  • <i>N</i>-Boc-4-piperidinemethanol