N-Boc-4-piperidinemethanol
- Product Name
- N-Boc-4-piperidinemethanol
- CAS No.
- 123855-51-6
- Chemical Name
- N-Boc-4-piperidinemethanol
- Synonyms
- TERT-BUTYL 4-(HYDROXYMETHYL)PIPERIDINE-1-CARBOXYLATE;N-BOC-piperidine-4-methanol;BOC-PIC(4)-OL;BUTTPARK 75\50-52;N-Boc-4-piperidineMe;Boc-4-Piperidine methanol;N-BOC-piperidin-4-Methanol;N-BOC-4-PIPERIDINEMETHANOL;BOC-ISONICOT(HEXAHYDRO)-OL;1-BOC-4-PIPERIDINEMETHANOL
- CBNumber
- CB2100290
- Molecular Formula
- C11H21NO3
- Formula Weight
- 215.29
- MOL File
- 123855-51-6.mol
N-Boc-4-piperidinemethanol Property
- Melting point:
- 78-82 °C (lit.)
- Boiling point:
- 308.0±15.0 °C(Predicted)
- Density
- 1.059±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- pka
- 14.94±0.10(Predicted)
- form
- Powder
- color
- White to brown
- InChI
- InChI=1S/C11H21NO3/c1-11(2,3)15-10(14)12-6-4-9(8-13)5-7-12/h9,13H,4-8H2,1-3H3
- InChIKey
- CTEDVGRUGMPBHE-UHFFFAOYSA-N
- SMILES
- N1(C(OC(C)(C)C)=O)CCC(CO)CC1
- CAS DataBase Reference
- 123855-51-6(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 556017
- Product name
- N-Boc-4-piperidinemethanol
- Purity
- 97%
- Packaging
- 5g
- Price
- $138
- Updated
- 2023/06/20
- Product number
- B2364
- Product name
- 1-(tert-Butoxycarbonyl)-4-piperidinemethanol
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $17
- Updated
- 2024/03/01
- Product number
- B2364
- Product name
- 1-(tert-Butoxycarbonyl)-4-piperidinemethanol
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $32
- Updated
- 2024/03/01
- Product number
- H26650
- Product name
- 1-Boc-4-piperidinemethanol, 97%
- Packaging
- 5g
- Price
- $95.65
- Updated
- 2024/03/01
- Product number
- H26650
- Product name
- 1-Boc-4-piperidinemethanol, 97%
- Packaging
- 1g
- Price
- $28
- Updated
- 2021/12/16
N-Boc-4-piperidinemethanol Chemical Properties,Usage,Production
Chemical Properties
White to light brown solid
Uses
N-Boc-4-piperidinemethanol is an important piperidine derivative, which can be used in organic synthesis and pharmaceutical intermediates, It may be used to synthesize:
methyl 5-methoxy-4-(1-methylpiperidin-4-ylmethoxy)-2-nitrobenzoate
N-Boc-4-piperidinecarboxaldehyde
[1-(tert-butoxycarbonyl)piperidin-4-yl]methyl methanesulfonate
Involved in the synthesis of bradycardic agents.
Application
N-Boc-4-piperidinemethanol is a curcumin analogue that binds to the epidermal growth factor receptor (EGFR) and prevents the binding of ligands. In vitro studies have shown that it can inhibit tumor growth and induce apoptosis in cancer cells. The drug is also capable of inhibiting the proliferation of normal cells, which may be due to its ability to recruit EGFR from outside the cell membrane. This process triggers signaling events that lead to cell death.
General Description
N-Boc-4-piperidinemethanol contains a tert-butyloxycarbonyl (t-BOC)-protecting group. It can be synthesized from 4-piperidinemethanol via reaction with di-tert-butyldicarbonate.
N-Boc-4-piperidinemethanol Preparation Products And Raw materials
Raw materials
Preparation Products
N-Boc-4-piperidinemethanol Suppliers
- Tel
- 0531-82375878 15269101859
- 2710825968@qq.com
- Country
- China
- ProdList
- 297
- Advantage
- 58
- Tel
- 21-21-61026752 13918007836
- Fax
- 021-51685238
- sales@hoborchem.com
- Country
- China
- ProdList
- 345
- Advantage
- 60
- Tel
- 025-66099280 17798518460
- Fax
- (1)02557626880
- cfzhang@aikonchem.com
- Country
- China
- ProdList
- 19915
- Advantage
- 55
- Tel
- 0513-68015397; 15716293042
- Fax
- 0513-68015394
- sales12@btcpharm.com
- Country
- China
- ProdList
- 686
- Advantage
- 55
- Tel
- 0513-82104991 18068193575
- Fax
- QQ1907456386
- sales2@btcpharm.com
- Country
- China
- ProdList
- 1332
- Advantage
- 58
- Tel
- 0535-7295056 15692356085
- sdycc1234@163.com
- Country
- China
- ProdList
- 109
- Advantage
- 58
- Tel
- 86-021-50318510
- Fax
- 021-58650104
- Country
- China
- ProdList
- 69
- Advantage
- 55
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-61259108 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- +49 3493/605464
- Fax
- +49 3493/605470
- sales@intatrade.de
- Country
- Germany
- ProdList
- 3572
- Advantage
- 66
View Lastest Price from N-Boc-4-piperidinemethanol manufacturers
- Product
- N-(tert-Butoxycarbonyl)-4-piperidinemethanol 123855-51-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100 tons
- Release date
- 2023-11-02
- Product
- N-(tert-Butoxycarbonyl)-4-piperidinemethanol 123855-51-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100 tons
- Release date
- 2023-11-02
- Product
- N-(tert-Butoxycarbonyl)-4-piperidinemethanol 123855-51-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100 tons
- Release date
- 2023-11-02