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N-Boc-4-piperidinemethanol

Product Name
N-Boc-4-piperidinemethanol
CAS No.
123855-51-6
Chemical Name
N-Boc-4-piperidinemethanol
Synonyms
TERT-BUTYL 4-(HYDROXYMETHYL)PIPERIDINE-1-CARBOXYLATE;N-BOC-piperidine-4-methanol;BOC-PIC(4)-OL;BUTTPARK 75\50-52;N-Boc-4-piperidineMe;Boc-4-Piperidine methanol;N-BOC-piperidin-4-Methanol;N-BOC-4-PIPERIDINEMETHANOL;BOC-ISONICOT(HEXAHYDRO)-OL;1-BOC-4-PIPERIDINEMETHANOL
CBNumber
CB2100290
Molecular Formula
C11H21NO3
Formula Weight
215.29
MOL File
123855-51-6.mol
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N-Boc-4-piperidinemethanol Property

Melting point:
78-82 °C (lit.)
Boiling point:
308.0±15.0 °C(Predicted)
Density 
1.059±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Methanol
pka
14.94±0.10(Predicted)
form 
Powder
color 
White to brown
InChI
InChI=1S/C11H21NO3/c1-11(2,3)15-10(14)12-6-4-9(8-13)5-7-12/h9,13H,4-8H2,1-3H3
InChIKey
CTEDVGRUGMPBHE-UHFFFAOYSA-N
SMILES
N1(C(OC(C)(C)C)=O)CCC(CO)CC1
CAS DataBase Reference
123855-51-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Safety Statements 
24/25
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
556017
Product name
N-Boc-4-piperidinemethanol
Purity
97%
Packaging
5g
Price
$138
Updated
2023/06/20
TCI Chemical
Product number
B2364
Product name
1-(tert-Butoxycarbonyl)-4-piperidinemethanol
Purity
>98.0%(GC)
Packaging
1g
Price
$17
Updated
2024/03/01
TCI Chemical
Product number
B2364
Product name
1-(tert-Butoxycarbonyl)-4-piperidinemethanol
Purity
>98.0%(GC)
Packaging
5g
Price
$32
Updated
2024/03/01
Alfa Aesar
Product number
H26650
Product name
1-Boc-4-piperidinemethanol, 97%
Packaging
5g
Price
$95.65
Updated
2024/03/01
Alfa Aesar
Product number
H26650
Product name
1-Boc-4-piperidinemethanol, 97%
Packaging
1g
Price
$28
Updated
2021/12/16
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N-Boc-4-piperidinemethanol Chemical Properties,Usage,Production

Chemical Properties

White to light brown solid

Uses

N-Boc-4-piperidinemethanol is an important piperidine derivative, which can be used in organic synthesis and pharmaceutical intermediates, It may be used to synthesize:
methyl 5-methoxy-4-(1-methylpiperidin-4-ylmethoxy)-2-nitrobenzoate
N-Boc-4-piperidinecarboxaldehyde
[1-(tert-butoxycarbonyl)piperidin-4-yl]methyl methanesulfonate
Involved in the synthesis of bradycardic agents.

Application

N-Boc-4-piperidinemethanol is a curcumin analogue that binds to the epidermal growth factor receptor (EGFR) and prevents the binding of ligands. In vitro studies have shown that it can inhibit tumor growth and induce apoptosis in cancer cells. The drug is also capable of inhibiting the proliferation of normal cells, which may be due to its ability to recruit EGFR from outside the cell membrane. This process triggers signaling events that lead to cell death.

General Description

N-Boc-4-piperidinemethanol contains a tert-butyloxycarbonyl (t-BOC)-protecting group. It can be synthesized from 4-piperidinemethanol via reaction with di-tert-butyldicarbonate.

N-Boc-4-piperidinemethanol Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Boc-4-piperidinemethanol Suppliers

Americas 1 China 377 Europe 3 France 3 Germany 4 India 29 Italy 2 Japan 3 Russia 1 Switzerland 3 The Netherlands 1 Ukraine 1 United Kingdom 18 United States 55 Global 501
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28398
Advantage
80
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View Lastest Price from N-Boc-4-piperidinemethanol manufacturers

Nanjing Fred Technology Co., Ltd
Product
N-Boc-4-piperidineMethanol 123855-51-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1 ton
Release date
2023-12-20
Shanghai Affida new material science and technology center
Product
N-BOC-4-piperidinemethanol 123855-51-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99
Supply Ability
50000KG/month
Release date
2024-05-08
BTC Nantong Pharmaceuticals Technology Co.,Ltd
Product
N-Boc-4-piperidinemethanol 123855-51-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
Tons
Release date
2023-04-04

123855-51-6, N-Boc-4-piperidinemethanolRelated Search:

N-Boc-Piperidine-4-carboxylic acid methyl ester DROPERIDOL N-(tert-Butoxycarbonyl)-4-piperidone Haloperidol 2,2,6,6-Tetramethyl-4-piperidinol PHENCYCLIDINE-D5 HYDROCHLORIDE tert-Butyl acetate tert-Butyl peroxyacetate 4-Piperidinemethanol tert-Butanol 1-Boc-2-piperidinemethanol,1-N-Boc-2-piperidinemethanol,1-TERT-BUTOXYCARBONYL-2-PIPERIDINEMETHANOL, N-BOC-2-PIPERIDINEMETHANOL 1-TERT-BUTOXYCARBONYL-3-PIPERIDINEMETHANOL, N-BOC-3-PIPERIDINEMETHANOL,1-Boc-3-piperidinemethanol 1-Boc-4-(2-hydroxyethyl)piperidine N-BOC-4-Hydroxypiperidine tert-Butyl 4-methylenepiperidine-1-carboxylate 1-Boc-4-cyanopiperidine N-Boc-(2R,3R,4S)-dolaproine TERT-BUTYL N-(2-HYDROXYETHYL)CARBAMATE

  • 1-N-BOC-4-HYDROXYMETHYL-PIPERIDINE
  • 1-(TERT-BUTOXYCARBONYL)-4-(HYDROXYMETHYL)PIPERIDINE
  • 1-(TERT-BUTOXYCARBONYL)-4-PIPERIDINEMETHANOL
  • TERT-BUTYL 4-(HYDROXYMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE
  • TERT-BUTYL 4-(HYDROXYMETHYL)PIPERIDINE-1-CARBOXYLATE
  • N-T-BUTOXYCARBONYL-HEXAHYDROISONICOTINOL
  • N-T-BUTOXYCARBONYL-4-HYDROXYMETHYL-PIPERIDINE
  • N-T-BUTOXYCARBONYL-4-PIPECOLINOL
  • N-T-BUTOXYCARBONYL-4-PIPERIDINEMETHANOL
  • N-(TERT-BUTOXYCARBONYL)-4-(HYDROXYMETHYL)PIPERIDINE
  • N-(TERT-BUTOXYCARBONYL)-4-PIPERIDINEMETHANOL
  • 1-Boc-4-(hydroxymethyl)piperidine 1-Boc-4-piperidinemethanol 1-(tert-Butoxycarbonyl)-4-(hydroxymethyl)piperidine
  • N-Boc-4-piperidineMe
  • N-BOC-piperidine-4-methanol
  • 1-piperidinecarboxylic acid, 4-(hydroxymethyl)-, 1,1-dimet
  • N-Boc-4-piperidinemethanol ,97%
  • N-Boc-4-piperidinemethanol,N-tert-Butyloxycarbonyl-4-piperidinemethanol
  • 4-(Hydroxymethyl)piperidine, N-BOC protected 97%
  • 1-Boc-4-(hydroxymethyl)-p...
  • tert-Butyl 4-(hydroxymethyl)piperidine-1-carboxylate, 1-(tert-Butoxycarbonyl)-4-(hydroxymethyl)piperidine
  • t-Butyl 4-(hydroxymethyl)piperidine-1-carboxylate
  • tert-butyl 4-(hydroxyMethyl)piperidin-1-carboxylate
  • N-BOC-piperidin-4-Methanol
  • N-Boc-4-piperidineMethanol, 95+%
  • N - bok - 4 - piperidine Methanol
  • 1-Boc-4-piperidinemethanol Synonyms N-tert-Butyloxycarbonyl-4-piperidinemethanol
  • N-Boc-4-piperidinemethanol 97%
  • 1,1-Dimethylethyl 4-(hydroxymethyl)-1-piperidinecarboxylate
  • n-tert-butyloxycarbonyl-4-piperidinemethanol
  • N-BOC-4-HYDROXYLMETHYLENE-PIPERIDINE
  • N-BOC-4-HYDROXYMETHYLPIPERIDINE
  • N-BOC-4-PIPERIDINEMETHANOL
  • 1-N-Boc-4-piperidinemethanol
  • tert-Butyl 4-(hydroxymethyl)-1-piperidinecarboxylate
  • 1-(TERT-BUTOXYCARBONYL)-4-PYRROLIDINEMETHANOL
  • (1-Boc-Piperidin-4-yl)methanol
  • 1-TERT-BUTOXYCARBONYL-4-PIPERIDINEMETHANOL, N-BOC-4-PIPERIDINEMETHANOL
  • N-BOC-4-HYDROXYMETHYLPIPERDINE
  • N-(tert-Butoxycarbonyl)-4-(Hydroxymethyl)piperidine, 98 %
  • 1-Piperidinecarboxylic acid, 4-(hydroxymethyl)-, 1,1-dimethylethyl ester
  • 1-Boc-4-Hyroxymethyl-Piperidine
  • 4-Hydroxylmethyl-N-( tert-butylcarboxylate)piperidine
  • BUTTPARK 75\50-52
  • BOC-PIC(4)-OL
  • BOC-ISONICOT(HEXAHYDRO)-OL
  • 4-HYDROXYMETHYL-1-TERT-BUTOXYCARBONYLPIPERIDINE
  • 4-HYDROXYMETHYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
  • 4-(HYDROXYMETHYL)PIPERIDINE-N-BOC PROTECTED
  • 1-BOC-4-(HYDROXYMETHYL)PIPERIDINE
  • 1-BOC-4-PIPERIDINEMETHANOL
  • tert-Butyl 4-(hydroxymethyl)-1
  • 1-(tert-Butoxycarbonyl)-4-piperidinemethanol &gt
  • Boc-4-Piperidine methanol
  • N-Boc-4-piperidinyl alcohol
  • N-Boc 4-piperdine methanol
  • N-Boc-4-piperidinemethanol 123855-51-6
  • 4-Hydroxymethyl-piperidin-1-carboxylic acid tert-butyl ester
  • 123855-51-6