N-Boc-4-piperidinemethanol

ChemicalBook > CAS DataBase List > N-Boc-4-piperidinemethanol

N-Boc-4-piperidinemethanol

Product Name: N-Boc-4-piperidinemethanol
CAS No.: 123855-51-6
Chemical Name: N-Boc-4-piperidinemethanol
Synonyms: TERT-BUTYL 4-(HYDROXYMETHYL)PIPERIDINE-1-CARBOXYLATE;N-BOC-piperidine-4-methanol;BOC-PIC(4)-OL;BUTTPARK 75\50-52;N-Boc-4-piperidineMe;Boc-4-Piperidine methanol;N-BOC-piperidin-4-Methanol;N-BOC-4-PIPERIDINEMETHANOL;BOC-ISONICOT(HEXAHYDRO)-OL;1-BOC-4-PIPERIDINEMETHANOL
CBNumber: CB2100290
Molecular Formula: C11H21NO3
Formula Weight: 215.29
MOL File: 123855-51-6.mol

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N-Boc-4-piperidinemethanol Property

Melting point:: 78-82 °C (lit.)
Boiling point:: 308.0±15.0 °C(Predicted)
Density: 1.059±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: soluble in Methanol
pka: 14.94±0.10(Predicted)
form: Powder
color: White to brown
InChI: InChI=1S/C11H21NO3/c1-11(2,3)15-10(14)12-6-4-9(8-13)5-7-12/h9,13H,4-8H2,1-3H3
InChIKey: CTEDVGRUGMPBHE-UHFFFAOYSA-N
SMILES: N1(C(OC(C)(C)C)=O)CCC(CO)CC1
CAS DataBase Reference: 123855-51-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Safety Statements: 24/25
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 556017
Product name: N-Boc-4-piperidinemethanol
Purity: 97%
Packaging: 5g
Price: $138
Updated: 2023/06/20

TCI Chemical

Product number: B2364
Product name: 1-(tert-Butoxycarbonyl)-4-piperidinemethanol
Purity: >98.0%(GC)
Packaging: 1g
Price: $17
Updated: 2024/03/01

TCI Chemical

Product number: B2364
Product name: 1-(tert-Butoxycarbonyl)-4-piperidinemethanol
Purity: >98.0%(GC)
Packaging: 5g
Price: $32
Updated: 2024/03/01

Alfa Aesar

Product number: H26650
Product name: 1-Boc-4-piperidinemethanol, 97%
Packaging: 5g
Price: $95.65
Updated: 2024/03/01

Alfa Aesar

Product number: H26650
Product name: 1-Boc-4-piperidinemethanol, 97%
Packaging: 1g
Price: $28
Updated: 2021/12/16

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N-Boc-4-piperidinemethanol Chemical Properties,Usage,Production

Chemical Properties

White to light brown solid

Uses

N-Boc-4-piperidinemethanol is an important piperidine derivative, which can be used in organic synthesis and pharmaceutical intermediates, It may be used to synthesize:
methyl 5-methoxy-4-(1-methylpiperidin-4-ylmethoxy)-2-nitrobenzoate
N-Boc-4-piperidinecarboxaldehyde
[1-(tert-butoxycarbonyl)piperidin-4-yl]methyl methanesulfonate
Involved in the synthesis of bradycardic agents.

Application

N-Boc-4-piperidinemethanol is a curcumin analogue that binds to the epidermal growth factor receptor (EGFR) and prevents the binding of ligands. In vitro studies have shown that it can inhibit tumor growth and induce apoptosis in cancer cells. The drug is also capable of inhibiting the proliferation of normal cells, which may be due to its ability to recruit EGFR from outside the cell membrane. This process triggers signaling events that lead to cell death.

General Description

N-Boc-4-piperidinemethanol contains a tert-butyloxycarbonyl (t-BOC)-protecting group. It can be synthesized from 4-piperidinemethanol via reaction with di-tert-butyldicarbonate.

N-Boc-4-piperidinemethanol Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from N-Boc-4-piperidinemethanol manufacturers

Anhui Yiao New Material Technology Co., Ltd

Product: N-(tert-Butoxycarbonyl)-4-piperidinemethanol 123855-51-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100 tons
Release date: 2023-11-02

Anhui Yiao New Material Technology Co., Ltd

Product: N-(tert-Butoxycarbonyl)-4-piperidinemethanol 123855-51-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100 tons
Release date: 2023-11-02

Anhui Yiao New Material Technology Co., Ltd

Product: N-(tert-Butoxycarbonyl)-4-piperidinemethanol 123855-51-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100 tons
Release date: 2023-11-02

123855-51-6, N-Boc-4-piperidinemethanolRelated Search:

N-Boc-Piperidine-4-carboxylic acid methyl ester DROPERIDOL N-(tert-Butoxycarbonyl)-4-piperidone Haloperidol 2,2,6,6-Tetramethyl-4-piperidinol PHENCYCLIDINE-D5 HYDROCHLORIDE tert-Butyl acetate tert-Butyl peroxyacetate 4-Piperidinemethanol tert-Butanol 1-Boc-2-piperidinemethanol,1-N-Boc-2-piperidinemethanol,1-TERT-BUTOXYCARBONYL-2-PIPERIDINEMETHANOL, N-BOC-2-PIPERIDINEMETHANOL 1-TERT-BUTOXYCARBONYL-3-PIPERIDINEMETHANOL, N-BOC-3-PIPERIDINEMETHANOL,1-Boc-3-piperidinemethanol 1-Boc-4-(2-hydroxyethyl)piperidine N-BOC-4-Hydroxypiperidine tert-Butyl 4-methylenepiperidine-1-carboxylate 1-Boc-4-cyanopiperidine N-Boc-(2R,3R,4S)-dolaproine TERT-BUTYL N-(2-HYDROXYETHYL)CARBAMATE

1-N-BOC-4-HYDROXYMETHYL-PIPERIDINE

1-(TERT-BUTOXYCARBONYL)-4-(HYDROXYMETHYL)PIPERIDINE

1-(TERT-BUTOXYCARBONYL)-4-PIPERIDINEMETHANOL

TERT-BUTYL 4-(HYDROXYMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE

TERT-BUTYL 4-(HYDROXYMETHYL)PIPERIDINE-1-CARBOXYLATE

N-T-BUTOXYCARBONYL-HEXAHYDROISONICOTINOL

N-T-BUTOXYCARBONYL-4-HYDROXYMETHYL-PIPERIDINE

N-T-BUTOXYCARBONYL-4-PIPECOLINOL

N-T-BUTOXYCARBONYL-4-PIPERIDINEMETHANOL

N-(TERT-BUTOXYCARBONYL)-4-(HYDROXYMETHYL)PIPERIDINE

N-(TERT-BUTOXYCARBONYL)-4-PIPERIDINEMETHANOL

1-Boc-4-(hydroxymethyl)piperidine 1-Boc-4-piperidinemethanol 1-(tert-Butoxycarbonyl)-4-(hydroxymethyl)piperidine

N-Boc-4-piperidineMe

N-BOC-piperidine-4-methanol

1-piperidinecarboxylic acid, 4-(hydroxymethyl)-, 1,1-dimet

N-Boc-4-piperidinemethanol ,97%

N-Boc-4-piperidinemethanol,N-tert-Butyloxycarbonyl-4-piperidinemethanol

4-(Hydroxymethyl)piperidine, N-BOC protected 97%

1-Boc-4-(hydroxymethyl)-p...

tert-Butyl 4-(hydroxymethyl)piperidine-1-carboxylate, 1-(tert-Butoxycarbonyl)-4-(hydroxymethyl)piperidine

t-Butyl 4-(hydroxymethyl)piperidine-1-carboxylate

tert-butyl 4-(hydroxyMethyl)piperidin-1-carboxylate

N-BOC-piperidin-4-Methanol

N-Boc-4-piperidineMethanol, 95+%

N - bok - 4 - piperidine Methanol

1-Boc-4-piperidinemethanol Synonyms N-tert-Butyloxycarbonyl-4-piperidinemethanol

N-Boc-4-piperidinemethanol 97%

1,1-Dimethylethyl 4-(hydroxymethyl)-1-piperidinecarboxylate

n-tert-butyloxycarbonyl-4-piperidinemethanol

N-BOC-4-HYDROXYLMETHYLENE-PIPERIDINE

N-BOC-4-HYDROXYMETHYLPIPERIDINE

N-BOC-4-PIPERIDINEMETHANOL

1-N-Boc-4-piperidinemethanol

tert-Butyl 4-(hydroxymethyl)-1-piperidinecarboxylate

1-(TERT-BUTOXYCARBONYL)-4-PYRROLIDINEMETHANOL

(1-Boc-Piperidin-4-yl)methanol

1-TERT-BUTOXYCARBONYL-4-PIPERIDINEMETHANOL, N-BOC-4-PIPERIDINEMETHANOL

N-BOC-4-HYDROXYMETHYLPIPERDINE

N-(tert-Butoxycarbonyl)-4-(Hydroxymethyl)piperidine, 98 %

1-Piperidinecarboxylic acid, 4-(hydroxymethyl)-, 1,1-dimethylethyl ester

1-Boc-4-Hyroxymethyl-Piperidine

4-Hydroxylmethyl-N-( tert-butylcarboxylate)piperidine

BUTTPARK 75\50-52

BOC-PIC(4)-OL

BOC-ISONICOT(HEXAHYDRO)-OL

4-HYDROXYMETHYL-1-TERT-BUTOXYCARBONYLPIPERIDINE

4-HYDROXYMETHYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

4-(HYDROXYMETHYL)PIPERIDINE-N-BOC PROTECTED

1-BOC-4-(HYDROXYMETHYL)PIPERIDINE

1-BOC-4-PIPERIDINEMETHANOL

tert-Butyl 4-(hydroxymethyl)-1

1-(tert-Butoxycarbonyl)-4-piperidinemethanol &gt

Boc-4-Piperidine methanol

N-Boc-4-piperidinyl alcohol

N-Boc 4-piperdine methanol

N-Boc-4-piperidinemethanol 123855-51-6

4-Hydroxymethyl-piperidin-1-carboxylic acid tert-butyl ester

<i>N</i>-Boc-4-piperidinemethanol