N-BOC-4-Hydroxypiperidine

Product Name: N-BOC-4-Hydroxypiperidine
CAS No.: 109384-19-2
Chemical Name: N-BOC-4-Hydroxypiperidine
Synonyms: TERT-BUTYL 4-HYDROXYPIPERIDINE-1-CARBOXYLATE;1-BOC-4-HYDROXYPIPERIDINE;4-HYDROXY-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;N-(TERT-BUTOXYCARBONYL)-4-PIPERIDINOL;1-(TERT-BUTOXYCARBONYL)-4-HYDROXYPIPERIDINE;Boc-4-piperidinol;1-Bocpiperidin-4-ol;RARECHEM AH CK 0055;N-BOC-4-PIPERIDINOL;1-BOC-4-PIPERIDINOL
CBNumber: CB7382529
Molecular Formula: C10H19NO3
Formula Weight: 201.26
MOL File: 109384-19-2.mol

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N-BOC-4-Hydroxypiperidine Property

Melting point:: 61-65 °C (lit.)
Boiling point:: 292.3±33.0 °C(Predicted)
Density: 1.107±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Chloroform, Ethyl Acetate
pka: 14.80±0.20(Predicted)
form: Powder
color: White to cream
BRN: 7202094
InChI: InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-8(12)5-7-11/h8,12H,4-7H2,1-3H3
InChIKey: PWQLFIKTGRINFF-UHFFFAOYSA-N
SMILES: N1(C(OC(C)(C)C)=O)CCC(O)CC1
CAS DataBase Reference: 109384-19-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 495484
Product name: 1-Boc-4-hydroxypiperidine
Purity: 97%
Packaging: 5g
Price: $59.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: 495484
Product name: 1-Boc-4-hydroxypiperidine
Purity: 97%
Packaging: 25g
Price: $126
Updated: 2024/03/01

TCI Chemical

Product number: B2671
Product name: 1-(tert-Butoxycarbonyl)-4-hydroxypiperidine
Purity: >97.0%(GC)
Packaging: 5g
Price: $16
Updated: 2024/03/01

TCI Chemical

Product number: B2671
Product name: 1-(tert-Butoxycarbonyl)-4-hydroxypiperidine
Purity: >97.0%(GC)
Packaging: 25g
Price: $40
Updated: 2024/03/01

Alfa Aesar

Product number: L19275
Product name: 1-Boc-4-hydroxypiperidine, 98%
Packaging: 5g
Price: $66.6
Updated: 2023/06/20

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N-BOC-4-Hydroxypiperidine Chemical Properties,Usage,Production

Chemical Properties

White to cream powder

Uses

Used in a synthesis of N-heterocyclic alkyl ethers via the Mitsunobu reaction.

Uses

N-Boc-4-hydroxypiperidine is a 4-hydroxypyridine with a boc protecting group used in the preparation of neurologically active agents and other pharmaceutical compounds.

Preparation

A mixture of 4-hydroxypiperidine (10.0 g, 98. 9 mmol), aqueous sodiumhydrogen carbonate (150 mL, 1 M), DI-FERT-BUTYL dicarbonate (21. 6 g, 98.9 mmol) and dichloromethane was stirred for 15 h. The phases were separated and the product (N-BOC-4-Hydroxypiperidine) was isolated as an oil in quantitative yield (19.9 g).

N-BOC-4-Hydroxypiperidine Preparation Products And Raw materials

Raw materials

Preparation Products

4-Amino-1-Boc-piperidine

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N-BOC-4-Hydroxypiperidine Suppliers

Americas 1 Belgium 2 Canada 3 China 398 Europe 3 France 4 Germany 10 India 50 Japan 3 Russia 1 Switzerland 3 The Netherlands 1 United Kingdom 18 United States 75 Global 572

ASCHEM GmbH

Tel: --
Fax: --
Email: info@aschem.ch
Country: Switzerland
ProdList: 897
Advantage: 58

Matrix Fine Chemicals GmbH

Tel: --
Fax: --
Email: nfo@matrix-fine-chemicals.com
Country: Switzerland
ProdList: 6968
Advantage: 58

SIGMA-RBI

Tel: --
Fax: --
Country: Switzerland
ProdList: 6896
Advantage: 91

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View Lastest Price from N-BOC-4-Hydroxypiperidine manufacturers

Hebei Dangtong Import and export Co LTD

Product: N-BOC-4-Hydroxypiperidine 109384-19-2
Price: US $107.00-95.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2023-09-15

Shanghai Longyu Biotechnology Co., Ltd.

Product: N-BOC-4-hydroxypiperidine 109384-19-2
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99.99
Supply Ability: 200tons
Release date: 2024-11-20

Shaanxi Dideu Medichem Co. Ltd

Product: N-BOC-4-Hydroxypiperidine 109384-19-2
Price: US $0.00-0.00/KG
Min. Order: 1g
Purity: 99%
Supply Ability: 2000tons
Release date: 2019-12-31

109384-19-2, N-BOC-4-HydroxypiperidineRelated Search:

2,2,6,6-Tetramethyl-4-piperidinol Haloperidol N-Carbobenzyloxyglycine tert-Butyl peroxyacetate Triacetonediamine tert-Butyl acetate tert-Butanol 4-Cyanophenol DROPERIDOL 1-Boc-4-cyanopiperidine N-Boc-4-piperidinemethanol tert-Butyl 4-methylenepiperidine-1-carboxylate 1-Boc-3-piperidone Diphenoxylate 4-Hydroxypiperidine Carbonyl iron powder (2R,4S)-N-BOC-4-HYDROXYPIPERIDINE-2-CARBOXYLIC ACID METHYL ESTER 1-Boc-4-methanesulfonyloxypiperidine

1-Boc-4-piperidinol, tert-Butyl 4-hydroxy-1-piperidinecarboxylate

N-BOC-4-Hydroxypiperidine,97%

1-Boc-4-hydroxypiperidine ,98%

N-Boc-4hydropiperidine

1-(tert-Butoxycarbonyl)-4-hydroxypiperidine, tert-Butyl 4-hydroxypiperidine-1-carboxylate

N-Boc-4-hydroxy-1-piperidine

tert-butyl 4-hydroxypiperidin-1-carboxylate

1-Boc -4-hydroxypeiperidine

4-Hydroxy-1-(tert-butoxycarbonyl)piperidine

N-BOC-4-Hydroxypiperidine, 97% 25GR

N-BOC-4-Hydroxypiperidine, 97% 5GR

tert-butyl 4-hydro×ypiperidine-1-carbo×ylate

N-BOC-4-Hydroxypiper

1-Boc-4-hydroxypiperidine 1-Boc-4-piperidinol

1-(tert-Butyloxycarbonyl)-4-piperidinol

1-Bocpiperidin-4-ol

N - bok - 4 - hydroxy piperidine

N-BOC-4-Hydroxypiperidine N-(tert-Butoxycarbonyl)-4-hydroxypiperidine

t-Butyl 4-hydroxypiperidine-1-carboxylate

Boc-(4-hydroxy)piperidine≥ 99% (GC)

RARECHEM AH CK 0055

TERT-BUTYL 4-HYDROXYPIPERIDINE-1-CARBOXYLATE

TERT-BUTYL 4-HYDROXY-1-PIPERIDINECARBOXYLATE

N-(TERT-BUTOXYCARBONYL)-4-HYDROXYPIPERIDINE

N-(TERT-BUTOXYCARBONYL)-4-PIPERIDINOL

N-BOC-4-PIPERIDINOL

N-BOC-4-HYDROXYPIPERIDINE

N-BOC-4-HYDROXYLPIPERIDINE

1-TERT-BUTOXYCARBONYL-4-PIPERIDINOL

1-(TERT-BUTOXYCARBONYL)-4-HYDROXYPIPERIDINE

1-BOC-4-PIPERIDINOL

1-BOC-4-HYDROXYPIPERIDINE

1-PIPERIDINECARBOXYLIC ACID, 4-HYDROXY-,1,1-DIMETHYLETHYL ESTER

4-HYDROXY-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

BOC-(4-HYDROXY)-PIPERIDINE

1-N-Boc-4-hydroxypiperidine

TERT-BUTYL 4-HYDROXY-1-PIPERIDINE-CARBOX

Crizotinib Impurity 11

N-BOC-4-Hydroxypiperidine/1-Boc-4-piperidinol

4-Hydroxypiperidine, N-BOC protected 98+%

1-BOC-4-HYDROXYLPIPERIDINE

1-BOC-4-HYDROXYPIPERIDINE / 1-TERT-BUTOXYCARBONYL-4-HYDROXYPIPERIDINE

1-BOC-4-HYDROXY-PIPERIDINE, 1-TERT-BUTOXYCARBONYL-4-HYDROXY-PIPERIDINE 99%

1-BOC-4-HYDROXYPIPERIDINE 99%

4-Hydroxypiperidine, N-BOC protected

N-(tert-butyloxycarbonyl)-4-piperidinol

(R-TERT-BUTYL 3-(HYDROXYMETHYLPYRROLIDINE-1-

1-(tert-Butoxycarbonyl)-4-hydroxypiperidine &gt

N-Boc-4-Hydroxypiperidine,>98%

Ibrutinib Impurity 53

N-tert-Butoxycarbonyl-4-hydroxy piperidine(N-BOC-4H)

Ibrutinib Impurity 63

N-Tert.Butoxycarbonyl-4-Hydroxy piperidine (or) N-boc-4-hydroxy piperidine

N-BOC-4-Hydroxypiperidinex

Boc-4-piperidinol

N-BOC-4-Hydroxypiperidine 109384-19-2

Pozitinib intermediate 6

4-Hydroxy-piperidin-1-carboxylic acid tert-butyl ester