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NARINGENIN

Product Name
NARINGENIN
CAS No.
67604-48-2
Chemical Name
NARINGENIN
Synonyms
5,7-DIHYDROXY-2-(4-HYDROXYPHENYL)CHROMAN-4-ONE;rac Naringenin;BE-14348A;()-Naringenin;Naringenin-RM;D4-Naringenin;(±)-Naringenin;(R,S)-Naringenin;TIMTEC-BB SBB006461;Naringenin Standard
CBNumber
CB8325312
Molecular Formula
C15H12O5
Formula Weight
272.25
MOL File
67604-48-2.mol
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NARINGENIN Property

Melting point:
247-250 °C (lit.)
Boiling point:
577.5±50.0 °C(Predicted)
Density 
1.485
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
7.52±0.40(Predicted)
form 
Solid
color 
Pale Yellow to Pale Brown
biological source
Citrus paradisi Macf.
Water Solubility 
Soluble in ethanol (50 mg/ml), DMSO, methanol, and ammonium hydroxide (50 mg/ml). Insoluble in water (almost)
Merck 
14,6424
InChI
InChI=1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2
InChIKey
FTVWIRXFELQLPI-UHFFFAOYSA-N
SMILES
C1(C2=CC=C(O)C=C2)OC2=CC(O)=CC(O)=C2C(=O)C1
CAS DataBase Reference
67604-48-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
3077
WGK Germany 
3
RTECS 
DJ2981530
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W530098
Product name
Naringenin
Purity
natural (US), 98%
Packaging
1 unit
Price
$49.38
Updated
2025/07/31
Sigma-Aldrich
Product number
W530098
Product name
Naringenin
Purity
natural (US), 98%
Packaging
1 unit
Price
$49.38
Updated
2025/07/31
Sigma-Aldrich
Product number
N5893
Product name
(±)-Naringenin
Purity
≥95%
Packaging
1g
Price
$58.2
Updated
2025/07/31
Sigma-Aldrich
Product number
52186
Product name
(±)-Naringenin
Purity
analytical standard
Packaging
50mg
Price
$155
Updated
2025/07/31
TCI Chemical
Product number
N0072
Product name
Naringenin
Purity
>93.0%(HPLC)(T)
Packaging
5g
Price
$66
Updated
2025/07/31
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NARINGENIN Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow to Pale Brown Solid

Uses

A PI 3-kinase inhibitor.

Uses

The aglucon of Naringin. Inhibitory mechanism of Naringenin against carcinogenic acrylamide formation and nonenzymic browning in Maillard model reactions.

Definition

ChEBI: Naringenin is a trihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5, 6 and 4'. It is a trihydroxyflavanone and a member of 4'-hydroxyflavanones.

General Description

Naringenin is a bioactive flavonoid found in citrus and grapefruit.

in vivo

(±)-Naringenin (50 mg/kg, orally, once a day for ten days) significantly reduces the severity of DSS-induced colitis in mice and downregulats pro-inflammatory mediators (iNOS, ICAM-1, MCP-1, Cox2, TNF-α, and IL-6 mRNA) in the colonic mucosa[2].

Animal Model:C57BL/6[2]
Dosage:50 mg/kg
Administration:Oral; daily; 10 days
Result:Reduced the severity of DSS-induced colitis in mice, downregulated pro-inflammatory mediators (iNOS, ICAM-1, MCP-1, Cox2, TNF-α, and IL-6 mRNA) in the colonic mucosa, inhibited the increase in TLR4 mRNA and protein levels, and reduced the phosphorylated NF-κB p65 protein level.

IC 50

NF-κB; Caspase 9

NARINGENIN Preparation Products And Raw materials

Raw materials

Preparation Products

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NARINGENIN Suppliers

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View Lastest Price from NARINGENIN manufacturers

Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd.
Product
Naringenin 67604-48-2
Price
US $172.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
50kg
Release date
2020-06-13
Baoji Guokang Healthchem co.,ltd
Product
NARINGENIN 67604-48-2
Price
US $80.00/kg/bag
Min. Order
1公斤/袋
Purity
98%
Supply Ability
5000T
Release date
2021-06-07
Zhuozhou Wenxi import and Export Co., Ltd
Product
(+/-)-Naringenin >=95% 67604-48-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

67604-48-2, NARINGENINRelated Search:


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  • TIMTEC-BB SBB006461
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  • 5,7-DIHYDROXY-2-(4-HYDROXYPHENYL)CHROMAN-4-ONE
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  • 4μ,5,7-Trihydroxyflavanone, (±)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
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  • 2-(4-Hydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-1-benzopyran-4-one
  • 4',5,7-Trihydroxy-2,3-dihydroflavone
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  • Potassium Channel,inhibit,(±)Naringenin,(±)-Naringenin,myocytes,vasorelaxant,(±) Naringenin,Inhibitor,KcsA
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  • 67604-48-2
  • Chemopreventive Agents
  • Cancer Research
  • BioChemical
  • Flavonoids
  • Enzyme Inhibitors
  • and Flavanols
  • Benzopyrans
  • Bioactive Small Molecules
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  • Chemical Synthesis
  • Citrus aurantium (Seville orange)
  • Flavonols
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