NARINGENIN
- Product Name
- NARINGENIN
- CAS No.
- 67604-48-2
- Chemical Name
- NARINGENIN
- Synonyms
- 5,7-DIHYDROXY-2-(4-HYDROXYPHENYL)CHROMAN-4-ONE;rac Naringenin;BE-14348A;()-Naringenin;Naringenin-RM;D4-Naringenin;(±)-Naringenin;(R,S)-Naringenin;TIMTEC-BB SBB006461;Naringenin Standard
- CBNumber
- CB8325312
- Molecular Formula
- C15H12O5
- Formula Weight
- 272.25
- MOL File
- 67604-48-2.mol
NARINGENIN Property
- Melting point:
- 247-250 °C (lit.)
- Boiling point:
- 577.5±50.0 °C(Predicted)
- Density
- 1.485
- storage temp.
- 2-8°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 7.52±0.40(Predicted)
- form
- Solid
- color
- Pale Yellow to Pale Brown
- biological source
- Citrus paradisi Macf.
- Water Solubility
- Soluble in ethanol (50 mg/ml), DMSO, methanol, and ammonium hydroxide (50 mg/ml). Insoluble in water (almost)
- Merck
- 14,6424
- InChI
- InChI=1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2
- InChIKey
- FTVWIRXFELQLPI-UHFFFAOYSA-N
- SMILES
- C1(C2=CC=C(O)C=C2)OC2=CC(O)=CC(O)=C2C(=O)C1
- CAS DataBase Reference
- 67604-48-2(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- W530098
- Product name
- Naringenin
- Purity
- natural (US), 98%
- Packaging
- 1 unit
- Price
- $49.38
- Updated
- 2025/07/31
- Product number
- W530098
- Product name
- Naringenin
- Purity
- natural (US), 98%
- Packaging
- 1 unit
- Price
- $49.38
- Updated
- 2025/07/31
- Product number
- N5893
- Product name
- (±)-Naringenin
- Purity
- ≥95%
- Packaging
- 1g
- Price
- $58.2
- Updated
- 2025/07/31
- Product number
- 52186
- Product name
- (±)-Naringenin
- Purity
- analytical standard
- Packaging
- 50mg
- Price
- $155
- Updated
- 2025/07/31
- Product number
- N0072
- Product name
- Naringenin
- Purity
- >93.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $66
- Updated
- 2025/07/31
NARINGENIN Chemical Properties,Usage,Production
Chemical Properties
Pale Yellow to Pale Brown Solid
Uses
A PI 3-kinase inhibitor.
Uses
The aglucon of Naringin. Inhibitory mechanism of Naringenin against carcinogenic acrylamide formation and nonenzymic browning in Maillard model reactions.
Definition
ChEBI: Naringenin is a trihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5, 6 and 4'. It is a trihydroxyflavanone and a member of 4'-hydroxyflavanones.
General Description
Naringenin is a bioactive flavonoid found in citrus and grapefruit.
in vivo
(±)-Naringenin (50 mg/kg, orally, once a day for ten days) significantly reduces the severity of DSS-induced colitis in mice and downregulats pro-inflammatory mediators (iNOS, ICAM-1, MCP-1, Cox2, TNF-α, and IL-6 mRNA) in the colonic mucosa[2].
| Animal Model: | C57BL/6[2] |
| Dosage: | 50 mg/kg |
| Administration: | Oral; daily; 10 days |
| Result: | Reduced the severity of DSS-induced colitis in mice, downregulated pro-inflammatory mediators (iNOS, ICAM-1, MCP-1, Cox2, TNF-α, and IL-6 mRNA) in the colonic mucosa, inhibited the increase in TLR4 mRNA and protein levels, and reduced the phosphorylated NF-κB p65 protein level. |
IC 50
NF-κB; Caspase 9
NARINGENIN Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from NARINGENIN manufacturers
- Product
- Naringenin 67604-48-2
- Price
- US $172.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 50kg
- Release date
- 2020-06-13
- Product
- NARINGENIN 67604-48-2
- Price
- US $80.00/kg/bag
- Min. Order
- 1公斤/袋
- Purity
- 98%
- Supply Ability
- 5000T
- Release date
- 2021-06-07
- Product
- (+/-)-Naringenin >=95% 67604-48-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27