ChemicalBook > CAS DataBase List > ROSE BENGAL LACTONE

ROSE BENGAL LACTONE

Product Name
ROSE BENGAL LACTONE
CAS No.
4159-77-7
Chemical Name
ROSE BENGAL LACTONE
Synonyms
Solvent Red 141;ROSE BENGAL LACTONE;4’,5’,7’-tetraiodo-droxy-2;C.I.Solvent Red 141:C.I.45440:1;4,5,6,7-Tetrachloro-2’,4’,5’,7’-tetraiodofluorescein;spiro[isobenzofuran-1(3h),9’-[9h]xanthen]-3-one,4,5,6,7-tetrachloro-3’,6’-dihy;4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro[2-benzofuran-3,9'-xanthene]-1-one;4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one;4',5',6',7'-Tetrachloro-3,6-dihydroxy-2,4,5,7-tetraiodospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one;3,6-Dihydroxy-2,4,5,7-tetraiodo-4',5',6',7'-tetrachlorospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
CBNumber
CB8331887
Molecular Formula
C20H4Cl4I4O5
Formula Weight
973.67
MOL File
4159-77-7.mol
More
Less

ROSE BENGAL LACTONE Property

Melting point:
280 °C (dec.)(lit.)
storage temp. 
room temp
Boiling point:
741.8±60.0 °C(Predicted)
Density 
2.96±0.1 g/cm3(Predicted)
pka
7.03±0.20(Predicted)
form 
powder
color 
pink to red
λmax
557 nm
ε(extinction coefficient)
≥10000 at 317-323nm
≥30000 at 516-522nm
≥95000 at 554-560nm
EPA Substance Registry System
Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo- (4159-77-7)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
328960
Product name
Rose Bengal lactone
Purity
95%
Packaging
1g
Price
$116
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
DYE0000553
Product name
ROSE BENGAL LACTONE
Purity
95.00%
Packaging
1G
Price
$626.43
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
DYE0000553
Product name
ROSE BENGAL LACTONE
Purity
95.00%
Packaging
5G
Price
$1163.45
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
DYE0000553
Product name
ROSE BENGAL LACTONE
Purity
95.00%
Packaging
10G
Price
$1765.08
Updated
2021/12/16
Chem-Impex
Product number
42054
Product name
RoseBengallactone,≥94%(HPLC),suitableforHematology&Histology
Purity
≥94%(HPLC)
Packaging
1G
Price
$95.51
Updated
2021/12/16
More
Less

ROSE BENGAL LACTONE Chemical Properties,Usage,Production

Description

Rose bengal lactone is a potent inhibitor of human metabolism that binds to the proteasome pathway and inhibits the polymerization of tubulin. It has been shown to bind with high affinity to microtubules and inhibit their assembly, which leads to cell death. Rose bengal lactone also binds with high affinity to potassium ion, which may contribute to its anti-cancer effects. This compound has also been found to be an effective inhibitor of goiters in rats by binding with aliphatic hydrocarbons such as cholesterol.

Chemical Properties

Bluish-pink powder. Soluble in water.

Uses

Biological stain; colorant for inks, cellulosics, foods, cosmetics, medicine (diagnostic aid).

Preparation

will Resorcinol and 4,5,6,7-Tetrachloroisobenzofuran-1,3-dione condensation, The resulting 4,5,6,7 – tetrachloro-fluorescein tetraiodide.

Properties and Applications

blue light red. Soluble in water for blue light yellow, no fluorescence, in concentrated sulfuric acid for brown, dilution after hot pink precipitation. Used in cosmetics coloring.

Standard Light Fastness Heat-resistant(℃) water Sodium Carbonate(5%) Hydrochloric acid(5%)
Melting point Stable
ISO Poor Insoluble

ROSE BENGAL LACTONE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

ROSE BENGAL LACTONE Suppliers

Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
Alfa Chemistry
Tel
--
Fax
--
Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
Frontier Scientific Services, Inc.
Tel
--
Fax
--
Email
customerservice@frontierssi.com
Country
United States
ProdList
1575
Advantage
0
Amfinecom Inc.
Tel
--
Fax
--
Email
sales@amfinecom.com
Country
United States
ProdList
3062
Advantage
50
Reagent World
Tel
--
Fax
--
Email
Sales@ReagentWorld.com
Country
United States
ProdList
1637
Advantage
50
Panslavia Chemicals, LLC
Tel
--
Fax
--
Country
United States
ProdList
310
Advantage
50
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
ASDI Incorporated
Tel
--
Fax
--
Email
customerservice@asdi.net
Country
United States
ProdList
6922
Advantage
67

4159-77-7, ROSE BENGAL LACTONERelated Search:


  • 4’,5’,7’-tetraiodo-droxy-2
  • spiro[isobenzofuran-1(3h),9’-[9h]xanthen]-3-one,4,5,6,7-tetrachloro-3’,6’-dihy
  • ROSE BENGAL LACTONE
  • 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one
  • 2,4,5,7-Tetraiodo-3,6-dihydroxy-4',5',6',7'-tetrachlorospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
  • 3,6-Dihydroxy-2,4,5,7-tetraiodo-4',5',6',7'-tetrachlorospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
  • 4',5',6',7'-Tetrachloro-3,6-dihydroxy-2,4,5,7-tetraiodospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
  • Solvent Red 141
  • 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro[2-benzofuran-3,9'-xanthene]-1-one
  • C.I.Solvent Red 141:C.I.45440:1
  • 4,5,6,7-Tetrachloro-2’,4’,5’,7’-tetraiodofluorescein
  • 4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one
  • 4159-77-7
  • C20H4Cl4I4O5
  • Q-R
  • Stains and Dyes
  • Stains&Dyes, A to