ChemicalBook > CAS DataBase List > 2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER

2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER

Product Name
2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER
CAS No.
660867-80-1
Chemical Name
2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER
Synonyms
CAS:660867-80-1;2-Methylpyridine-4-;2-aMino-4-pyridine boronic ester;2-Picoline-4-boronic acid pinacolate;2-Picoline-4-boronic acid pinacol ester;2-Methylpyridine-4-boronic acid pinacol;2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER;2-Methyl-4-pyridineboronic acid pinacol ester;2-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine;2-(2-Methyl-4-pyridyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CBNumber
CB8332208
Molecular Formula
C12H18BNO2
Formula Weight
219.09
MOL File
660867-80-1.mol
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2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER Property

Melting point:
66-71°C
Boiling point:
315.9±30.0 °C(Predicted)
Density 
1.02
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
soluble in Methanol
form 
powder to crystal
pka
5.11±0.10(Predicted)
color 
White to Almost white
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Safety

Hazard Codes 
Xi
Risk Statements 
37/38-41
Safety Statements 
26-39
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CDS007583
Product name
2-methylpyridine-4-boronic acid pinacol ester
Purity
Aldrich<SUP>CPR</SUP>
Packaging
500 mg
Price
$107
Updated
2025/07/31
TCI Chemical
Product number
M2867
Product name
2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
Purity
>98.0%(T)
Packaging
1g
Price
$146
Updated
2025/07/31
TCI Chemical
Product number
M2867
Product name
2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
Purity
>98.0%(T)
Packaging
5g
Price
$583
Updated
2025/07/31
AK Scientific
Product number
X0928
Product name
2-Methylpyridine-4-boronicacidpinacolester
Packaging
10g
Price
$321
Updated
2021/12/16
SynQuest Laboratories
Product number
8H60-1-6M
Product name
2-Methylpyridine-4-boronic acid, pinacol ester
Packaging
5G
Price
$160
Updated
2021/12/16
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2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER Chemical Properties,Usage,Production

Synthesis

22282-99-1

73183-34-3

660867-80-1

The general procedure for the synthesis of 2-methyl-4-pyridylboronic acid pinacol ester from 4-bromo-2-methylpyridine (0.500 g, 2.906 mmol) and pinacol ester of bis(diphenylphosphine) (0.812 g, 3.997 mmol) is as follows: in an inert atmosphere, 4-bromo-2-methylpyridine, pinacol ester of bis(boronic acid), potassium acetate (0.854 g, 8.720 mmol) and [1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloride (0.021 g, 0.029 mmol) were dissolved in degassed 1,4-dioxane (5 mL) in a 50 mL sealed tube. The reaction mixture was stirred at 80 °C for 4 hours. Upon completion of the reaction, the solvent was removed by rotary evaporation and the crude product was purified by silica gel column chromatography (eluent: ethyl acetate/ether = 30:70) to afford 2-methyl-4-pyridinylboronic acid pinacol ester (0.250 g, 39% yield) as an off-white solid. m/z 220.1 [M + H]+ was shown by LCMS analysis.

References

[1] Patent: WO2014/111871, 2014, A1. Location in patent: Page/Page column 199
[2] Patent: WO2004/14913, 2004, A2. Location in patent: Page 82
[3] Patent: US2011/190269, 2011, A1. Location in patent: Page/Page column 36
[4] Patent: WO2011/92272, 2011, A1. Location in patent: Page/Page column 73
[5] Patent: WO2011/119518, 2011, A1. Location in patent: Page/Page column 47-48

2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER manufacturers

Henan Fengda Chemical Co., Ltd
Product
2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER 660867-80-1
Price
US $36.00-1.10/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08
Dideu Industries Group Limited
Product
2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER 660867-80-1
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-08-26
Career Henan Chemical Co
Product
2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER 660867-80-1
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-01-13

660867-80-1, 2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTERRelated Search:

2-CHLORO-3-METHYLPYRIDINE-5-BORONIC ACID PINACOL ESTER 2-ACETYLPYRIDINE-4-BORONIC ACID PINACOL ESTER 1-METHYL-5-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDIN-2-YL]PIPERAZINE 2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER 6-Methylpyridine-3-boronic acid pinacol ester,2-Methylpyridine-5-boronic acid pinacol ester 2-Methylpyridine-4-boronic acid 2-CYANOPYRIDINE-4-BORONIC ACID PINACOL ESTER 2-(Methoxycarbonyl)-4-pyridineboronic acid, pinacol ester ETHYL PYRIDINE-4-BORONIC ACID PINACOL ESTER-2-CARBOXYLATE 2-ETHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER 2-CHLORO-6-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER 2-(TRIFLUOROMETHYL)PYRIDINE-4-BORONIC ACID PINACOL ESTER 2-FLUORO-6-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER 2-PHENYLPYRIDINE-4-BORONIC ACID PINACOL ESTER 2-METHYLPYRIDINE-3-BORONIC ACID PINACOL ESTER 2-BROMO-5-METHYLPYRIDINE-3-BORONIC ACID PINACOL ESTER 2-FLUORO-5-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER 6-TERT-BUTYLOXYCARBONYLAMINO-2-METHYLPYRIDINE-3-BORONIC ACID PINACOL ESTER

  • 2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER
  • 2-METHYL-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE
  • 2-Picoline-4-boronic acid pinacol ester
  • 2-Picoline-4-boronic acid pinacolate
  • 2-Methyl-4-pyridineboronic acid pinacol ester
  • 2-Methylpyridine-4-boronic acid pinacol
  • 2-Methylpyridine-4-boronic acid pinacol ester, 95%, May contain up to 3% water
  • 2-aMino-4-pyridine boronic ester
  • 2-Methylpyridine-4-
  • Pyridine, 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
  • 2-(2-Methyl-4-pyridyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • 2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER ISO 9001：2015 REACH
  • 2-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
  • CAS:660867-80-1
  • 660867-80-1
  • 660876-80-1
  • Organic boronic acid
  • Boronic ester
  • Organoborons
  • Pyridine