PF-06471553

Product Name: PF-06471553
CAS No.: 1808094-07-6
Chemical Name: PF-06471553
Synonyms: PF-06471553;PF 06471553,PF06471553;1H-Isoindole-5-sulfonamide, N-(2-cyclobutyl-2H-1,2,3-triazol-4-yl)-2,3-dihydro-2-[2-(3-methoxyphenyl)acetyl]-
CBNumber: CB83355457
Molecular Formula: C23H25N5O4S
Formula Weight: 467.54
MOL File: 1808094-07-6.mol

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PF-06471553 Property

Boiling point:: 728.7±70.0 °C(Predicted)
Density: 1.46±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : ≥ 150 mg/mL (320.83 mM)
form: Solid
pka: 6.75±0.20(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0028403
Product name: PF-06471553
Purity: 98.29%
Packaging: 5mg
Price: $550
Updated: 2021/12/16

ChemScene

Product number: CS-0028403
Product name: PF-06471553
Purity: 98.29%
Packaging: 10mg
Price: $850
Updated: 2021/12/16

ChemScene

Product number: CS-0028403
Product name: PF-06471553
Purity: 98.29%
Packaging: 25mg
Price: $1750
Updated: 2021/12/16

ChemScene

Product number: CS-0028403
Product name: PF-06471553
Purity: 98.29%
Packaging: 50mg
Price: $2750
Updated: 2021/12/16

ChemScene

Product number: CS-0028403
Product name: PF-06471553
Purity: 98.29%
Packaging: 100mg
Price: $3950
Updated: 2021/12/16

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PF-06471553 Chemical Properties,Usage,Production

Description

PF-06471553 is a potent and selective Monoacylglycerol acyltransferase 3 (MGAT3) inhibitor. PF-06471553 selectively inhibits MGAT3 with high in vitro potency and cell efficacy. In the presence of a combination of diacylglycerol acyltransferases 1 and 2 (DGAT1 and DGAT2) inhibitors, an oral administration of PF-06471553 exhibited inhibition of the incorporation of deuterium-labeled glycerol into TAG in mouse model. Inhibition of triacylglycerol (TAG) biosynthetic enzymes has been suggested as a promising strategy to treat insulin resistance, diabetes, dyslipidemia, and hepatic steatosis.

PF-06471553 Preparation Products And Raw materials

Raw materials

Preparation Products

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PF-06471553 Suppliers

China 16 United States 2 Global 18

Nanjing Norris-Pharm Technology Co., Ltd

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Shanghai EFE Biological Technology Co., Ltd.

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Fan De(Beijing) Biotechnology Co., Ltd.

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Shanghai Akasaka Biotechnology Co., Ltd.

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Nanjing Meihao Pharmaceutical Technology Co., Ltd.

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TargetMol Chemicals Inc.

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InvivoChem

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1808094-07-6, PF-06471553Related Search:

PF-06471553

PF 06471553,PF06471553

1H-Isoindole-5-sulfonamide, N-(2-cyclobutyl-2H-1,2,3-triazol-4-yl)-2,3-dihydro-2-[2-(3-methoxyphenyl)acetyl]-

1808094-07-6