NAI-N3
- Product Name
- NAI-N3
- CAS No.
- 1612756-29-2
- Chemical Name
- NAI-N3
- Synonyms
- NAI 1;NAI-N3;[2-(Azidomethyl)-3-pyridinyl]-1H-imidazol-1-yl-methanone
- CBNumber
- CB83356166
- Formula Weight
- 0
- MOL File
- Mol file
NAI-N3 Property
- storage temp.
- Store at -20°C
- solubility
- Ethanol:16.67(Max Conc. mg/mL);73.05(Max Conc. mM)
DMSO:250.0(Max Conc. mg/mL);1095.46(Max Conc. mM) - form
- Solid
- color
- White to Pale Beige
- Stability:
- Light sensitive, Moisture sensitive
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P314Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P322Specific measures (see …on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 7003
- Product name
- NAI-N3
- Packaging
- 25
- Price
- $245
- Updated
- 2021/12/16
- Product number
- N215005
- Product name
- NAI1
- Packaging
- 500mg
- Price
- $1750
- Updated
- 2021/12/16
NAI-N3 Chemical Properties,Usage,Production
Description
NAI-N3 is a probe for icSHAPE (in vivo click selective 2'-hydroxyl acylation and profiling experiment). It acylates the 2'-OH in ssRNA and enables RNA structure profiling in vivo and ex vivo for all four bases. NAI-N3 can be used for site-specific RNA acylation using the RAIL (RNA Acylation at Induced Loops) method or in Apta-Seq to discover new aptamers in selected pools.
Uses
NAI 1 is used in the process of visualizing the physical basis for molecular behaviours inside living cells. RNAs are central to biological regulation and this molecule aids in the first global view of RNA secondary structures in living cells for all four bases.
in vitro
In brief, the bifunctional NAI-N3 SHAPE reagent is used to label all RNAs inside living cells (or in vitro refolded RNA) to generate covalent modifications on targeted RNAs at single-nucleotide resolution. _x000D_ _x000D_ Reference: Nat Protoc. 2016 Feb;11(2):273-90. https://pubmed.ncbi.nlm.nih.gov/26766114/
in vivo
This study has tested the NAI-N3 reagent in bacterial (Gram-negative Escherichia coli), yeast, insect and mammalian cells for SHAPE experiments. All of these systems proved to be amenable for icSHAPE modification and RNA structure determination. This study has successfully generated icSHAPE data from experiments in which the in vivo modification occurs at temperatures between 30 and 37 °C, to accommodate the specific culture temperatures. Thus, the procedure can be easily adapted to a wide variety of culture systems to allow transcriptome-wide RNA structure determination in most model systems._x000D_ _x000D_ Reference: Nat Protoc. 2016 Feb;11(2):273-90. https://pubmed.ncbi.nlm.nih.gov/26766114/
target
NAI-N3 is a RNA acylation reagent that enables RNA purification. NAI-N3 is a dual-function SHAPE (selective 2-hydroxyl acylation and profiling experiment) probe (RNA structure probe and enrichment).
NAI-N3 Preparation Products And Raw materials
Raw materials
Preparation Products
NAI-N3 Suppliers
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View Lastest Price from NAI-N3 manufacturers
- Product
- NAI-N3 1612756-29-2
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- >99.00%
- Supply Ability
- 5mg
- Release date
- 2024-03-22