NAI-N3

Product Name: NAI-N3
CAS No.: 1612756-29-2
Chemical Name: NAI-N3
Synonyms: NAI 1;NAI-N3;[2-(Azidomethyl)-3-pyridinyl]-1H-imidazol-1-yl-methanone
CBNumber: CB83356166
Formula Weight: 0
MOL File: Mol file

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NAI-N3 Property

storage temp.: Store at -20°C
solubility: Ethanol:16.67(Max Conc. mg/mL);73.05(Max Conc. mM)
DMSO:250.0(Max Conc. mg/mL);1095.46(Max Conc. mM)
form: Solid
color: White to Pale Beige
Stability:: Light sensitive, Moisture sensitive

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P314Get medical advice/attention if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Tocris

Product number: 7003
Product name: NAI-N3
Packaging: 25
Price: $245
Updated: 2021/12/16

TRC

Product number: N215005
Product name: NAI1
Packaging: 500mg
Price: $1750
Updated: 2021/12/16

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NAI-N3 Chemical Properties,Usage,Production

Description

NAI-N3 is a probe for icSHAPE (in vivo click selective 2'-hydroxyl acylation and profiling experiment). It acylates the 2'-OH in ssRNA and enables RNA structure profiling in vivo and ex vivo for all four bases. NAI-N3 can be used for site-specific RNA acylation using the RAIL (RNA Acylation at Induced Loops) method or in Apta-Seq to discover new aptamers in selected pools.

Uses

NAI 1 is used in the process of visualizing the physical basis for molecular behaviours inside living cells. RNAs are central to biological regulation and this molecule aids in the first global view of RNA secondary structures in living cells for all four bases.

in vitro

In brief, the bifunctional NAI-N3 SHAPE reagent is used to label all RNAs inside living cells (or in vitro refolded RNA) to generate covalent modifications on targeted RNAs at single-nucleotide resolution. _x000D_ _x000D_ Reference: Nat Protoc. 2016 Feb;11(2):273-90. https://pubmed.ncbi.nlm.nih.gov/26766114/

in vivo

This study has tested the NAI-N3 reagent in bacterial (Gram-negative Escherichia coli), yeast, insect and mammalian cells for SHAPE experiments. All of these systems proved to be amenable for icSHAPE modification and RNA structure determination. This study has successfully generated icSHAPE data from experiments in which the in vivo modification occurs at temperatures between 30 and 37 °C, to accommodate the specific culture temperatures. Thus, the procedure can be easily adapted to a wide variety of culture systems to allow transcriptome-wide RNA structure determination in most model systems._x000D_ _x000D_ Reference: Nat Protoc. 2016 Feb;11(2):273-90. https://pubmed.ncbi.nlm.nih.gov/26766114/

target

NAI-N3 is a RNA acylation reagent that enables RNA purification. NAI-N3 is a dual-function SHAPE (selective 2-hydroxyl acylation and profiling experiment) probe (RNA structure probe and enrichment).

NAI-N3 Preparation Products And Raw materials

Raw materials

Preparation Products

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NAI-N3 Suppliers

China 21 United States 6 Global 27

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View Lastest Price from NAI-N3 manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: NAI-N3 1612756-29-2
Price: US $0.00/mg
Min. Order: 5mg
Purity: >99.00%
Supply Ability: 5mg
Release date: 2024-03-22

1612756-29-2, NAI-N3Related Search:

[2-(Azidomethyl)-3-pyridinyl]-1H-imidazol-1-yl-methanone

NAI-N3

NAI 1

1612756-29-2