t-Boc-Aminooxy-PEG4-CH2CO2H

Product Name: t-Boc-Aminooxy-PEG4-CH2CO2H
CAS No.: 2028281-90-3
Chemical Name: t-Boc-Aminooxy-PEG4-CH2CO2H
Synonyms: t-Boc-Aminooxy-PEG4-CH2CO2H;t-Boc-Aminooxy-PEG4-CH2COOH;N-Boc-Aminooxy-PEG4-CH2COOH;t-Boc-Aminooxy-PEG4-CH2CO2H boc;3,6,9,12,15-Pentaoxa-2-azaheptadecanedioic acid, 1-(1,1-dimethylethyl) ester
CBNumber: CB83364004
Molecular Formula: C15H29NO9
Formula Weight: 367.39
MOL File: 2028281-90-3.mol

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t-Boc-Aminooxy-PEG4-CH2CO2H Property

Density: 1.166±0.06 g/cm3(Predicted)
pka: 3.39±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23353
Product name: t-Boc-Aminooxy-PEG4-CH2CO2H
Purity: 98%
Packaging: 100mg
Price: $320
Updated: 2021/12/16

BroadPharm

Product number: BP-23353
Product name: t-Boc-Aminooxy-PEG4-CH2CO2H
Purity: 98%
Packaging: 250mg
Price: $540
Updated: 2021/12/16

BroadPharm

Product number: BP-23353
Product name: t-Boc-Aminooxy-PEG4-CH2CO2H
Purity: 98%
Packaging: 500mg
Price: $780
Updated: 2021/12/16

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t-Boc-Aminooxy-PEG4-CH2CO2H Chemical Properties,Usage,Production

Description

t-Boc-Aminooxy-PEG4-CH2CO2H is a crosslinking reagent with a Boc-protected aminooxy group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU). The Boc-protected amine can be deprotected under mild acidic conditions. PEG4 spacer increases solubility in aqueous media.

Uses

Boc-Aminooxy-PEG4-CH2CO2H is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

Alkyl/ether; PEGs

References

[1] Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413. DOI:10.1124/pr.118.015651

t-Boc-Aminooxy-PEG4-CH2CO2H Preparation Products And Raw materials

Raw materials

Preparation Products

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t-Boc-Aminooxy-PEG4-CH2CO2H Suppliers

China 18 United States 2 Global 20

Jinan elephant international trading co., LTD

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2028281-90-3, t-Boc-Aminooxy-PEG4-CH2CO2HRelated Search:

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t-Boc-Aminooxy-PEG4-CH2CO2H

3,6,9,12,15-Pentaoxa-2-azaheptadecanedioic acid, 1-(1,1-dimethylethyl) ester

t-Boc-Aminooxy-PEG4-CH2CO2H boc

N-Boc-Aminooxy-PEG4-CH2COOH

t-Boc-Aminooxy-PEG4-CH2COOH

2028281-90-3

C15H29NO9