(2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid

Product Name: (2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid
CAS No.: 870487-08-4
Chemical Name: (2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid
Synonyms: Boc-Val-Cit;Boc-Val-Cit-OH;Boc-L-Val-Cit-OH;Boc-L-valyl-L-citrulline;N-Boc-L-valyl-N5-(aminocarbonyl)-L-ornithine;L-Ornithine, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-;(R)-2-((R)-2-((tert-butoxycarbonyl)amino)-3-methylbutanamido)-5-ureidopentanoic acid;ADC Linkers,Inhibitor,Boc Val Cit OH,BocValCitOH,Antibody-drug conjugates linkers,inhibit;(2S)-2-[[(2S)-2-(tert-butoxycarbonylamino)-3-methyl-butanoyl]amino]-5-ureido-pentanoic acid;(2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid
CBNumber: CB83373136
Molecular Formula: C16H30N4O6
Formula Weight: 374.43
MOL File: 870487-08-4.mol

More

Less

(2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid Property

Boiling point:: 624.8±55.0 °C(Predicted)
Density: 1.183±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
solubility: Soluble in DMSO
pka: 3.44±0.10(Predicted)
form: Solid
color: White to off-white
InChIKey: ZZLNUAVYYRBTOZ-QWRGUYRKSA-N
SMILES: C(O)(=O)[C@H](CCCNC(N)=O)NC(=O)[C@H](C(C)C)NC(OC(C)(C)C)=O

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

BroadPharm

Product number: bp-24173
Product name: Boc-Val-Cit
Purity: 99%
Packaging: 500MG
Price: $180
Updated: 2026/05/24

BroadPharm

Product number: bp-24173
Product name: Boc-Val-Cit
Purity: 99%
Packaging: 1G
Price: $240
Updated: 2026/05/24

BroadPharm

Product number: bp-24173
Product name: Boc-Val-Cit
Purity: 99%
Packaging: 5G
Price: $705
Updated: 2026/05/24

BroadPharm

Product number: bp-24173
Product name: Boc-Val-Cit
Purity: 99%
Packaging: 10G
Price: $1200
Updated: 2026/05/24

Synthonix

Product number: B63237
Product name: (S)-2-((S)-2-((tert-Butoxycarbonyl)amino)-3-methylbutanamido)-5-ureidopentanoic acid
Purity: >98%
Packaging: 1g
Price: $35
Updated: 2026/05/06

More

Less

(2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid Chemical Properties,Usage,Production

Description

Boc-Val-Cit is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. Boc group can be removed under acidic condition.

Uses

Boc-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC 50

Protease Cleavable Linker; Cleavable Linker

References

[1] Kevin HAMBLETT, et al. Anti-her2 biparatopic antibody-drug conjugates and methods of use. WO2019173911A1.

(2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid Suppliers

China 107 United States 6 Global 113

Kanghua (Shanghai) New Drug Development Co., Ltd.

Tel: 021-61263370 18516560301
Email: xingli@glbiochem.com
Country: China
ProdList: 5637
Advantage: 58

YangZhou Ruihong Biotech Co., Ltd.

Tel: 15380367604 15850576331
Email: 591834516@qq.com
Country: China
ProdList: 808
Advantage: 58

Sichuan Tongsheng Amino acids Co.,Ltd.

Tel: 0838-2274206 13908101207
Fax: +86-838-2274207
Email: sales@biots.cn
Country: China
ProdList: 279
Advantage: 66

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: marketing@accelachem.com
Country: China
ProdList: 10977
Advantage: 64

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9520
Advantage: 58

Emeishan Hongsen Biopharmaceutical Co., Ltd.

Tel: 0833-6186278 19162541913
Email: sales@hongshengpharm.com
Country: China
ProdList: 99
Advantage: 60

Tianjin Chempharmatech Co.,Ltd.

Tel: 022-66211079 13212288319
Fax: qq1405432731
Email: sales@chempharmatech.com
Country: China
ProdList: 925
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-400-164-7117 18317119277
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 40000
Advantage: 60

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66028182 17714375163
Email: yftan@aikonchem.com
Country: China
ProdList: 16676
Advantage: 50

Shanghai GL Peptide Ltd.

Tel: +86-21-61263340; 17609490614 13764994101
Fax: 021-61263399
Email: fisherwang@glschina.com
Country: China
ProdList: 8252
Advantage: 55

More

Less

View Lastest Price from (2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid manufacturers

Shanghai Joiny Pharmaceutical Co.,LTD

Product: Boc-Val-Cit-OH 870487-08-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2025-05-08

Xian confluore Biological Technology Co., Ltd.

Product: Boc-Val-Cit 870487-08-4
Price: US $0.00/g
Min. Order: 25g
Purity: >95.00%
Supply Ability: 25g
Release date: 2024-03-29

870487-08-4, (2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acidRelated Search:

(S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid

(2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid

Boc-Val-Cit-OH

Boc-Val-Cit

L-Ornithine, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-

(R)-2-((R)-2-((tert-butoxycarbonyl)amino)-3-methylbutanamido)-5-ureidopentanoic acid

Boc-L-valyl-L-citrulline

ADC Linkers,Inhibitor,Boc Val Cit OH,BocValCitOH,Antibody-drug conjugates linkers,inhibit

N-Boc-L-valyl-N5-(aminocarbonyl)-L-ornithine

Boc-L-Val-Cit-OH

(2S)-2-[[(2S)-2-(tert-butoxycarbonylamino)-3-methyl-butanoyl]amino]-5-ureido-pentanoic acid

870487-08-4

Linker

ADC LINKER