ChemicalBook > CAS DataBase List > (S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid
(S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid
- Product Name
- (S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid
- CAS No.
- 70396-18-8
- Chemical Name
- (S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid
- Synonyms
- (tert-Butoxycarbonyl)-L-valyl-L-alanine;Boc-Val-Ala;Boc-L-Val-Ala-OH;Boc-L-Valyl- L-Alanin;N-Boc-L-valyl- L-alanine;(Tert-Butoxy)Carbonyl Val-Ala-OH;L-Alanine, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-;(S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid;(S)-2-((S)-2-((tert-Butoxycarbonyl)amino)-3-methylbutylamide)propionic acid;(2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]propanoic acid
- CBNumber
- CB92561447
- Molecular Formula
- C13H24N2O5
- Formula Weight
- 288.34
- MOL File
- 70396-18-8.mol
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(S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid Property
- Boiling point:
- 493.3±30.0 °C(Predicted)
- Density
- 1.121±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- form
- Solid
- pka
- 3.50±0.10(Predicted)
- color
- White to off-white
- InChI
- InChI=1S/C13H24N2O5/c1-7(2)9(10(16)14-8(3)11(17)18)15-12(19)20-13(4,5)6/h7-9H,1-6H3,(H,14,16)(H,15,19)(H,17,18)/t8-,9-/m0/s1
- InChIKey
- FHBCSPANXVQYCP-IUCAKERBSA-N
- SMILES
- C(O)(=O)[C@H](C)NC(=O)[C@H](C(C)C)NC(OC(C)(C)C)=O
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
AK Scientific
- Product number
- 4510CV
- Product name
- (S)-2-((S)-2-(Tert-butoxycarbonylamino)-3-methylbutanamido)propanoicacid
- Packaging
- 1g
- Price
- $132
- Updated
- 2021/12/16
Ambeed
- Product number
- A266251
- Product name
- Boc-Val-Ala-OH
- Purity
- 95%
- Packaging
- 5g
- Price
- $198
- Updated
- 2021/12/16
Acrotein
- Product number
- NA-1269
- Product name
- N-Boc-L-valyl-L-alanine
- Purity
- 97%
- Packaging
- 5g
- Price
- $220
- Updated
- 2021/12/16
Acrotein
- Product number
- NA-1269
- Product name
- N-Boc-L-valyl-L-alanine
- Purity
- 97%
- Packaging
- 25g
- Price
- $660
- Updated
- 2021/12/16
Crysdot
- Product number
- CD22001871
- Product name
- Boc-Val-Ala-OH
- Purity
- 95+%
- Packaging
- 1g
- Price
- $923
- Updated
- 2021/12/16
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(S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid Chemical Properties,Usage,Production
Description
Boc-Val-Ala-OH is a cleavable ADC linker. The Val-Ala is effectively cleaved by lysosomal proteolytic enzymes while being highly stable in human plasma, making this a potentent stragy in ADC linker design. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Uses
(tert-Butoxycarbonyl)-L-valyl-L-alanine is an alanine derivative[1].
References
[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1080. DOI:10.1080/10408398.2012.708368
(S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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(S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid Suppliers
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View Lastest Price from (S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid manufacturers
Shanghai Joiny Pharmaceutical Co.,LTD
- Product
- Boc-Val-Ala-OH 70396-18-8
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2025-05-08
Sichuan HongRi Pharma-Tech Co.,Ltd
- Product
- Boc-Val-Ala 70396-18-8
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%+
- Supply Ability
- 1T+
- Release date
- 2024-04-10
Xian confluore Biological Technology Co., Ltd.
- Product
- Boc-Val-Ala-OH 70396-18-8
- Price
- US $0.00/g
- Min. Order
- 25g
- Purity
- >95.00%
- Supply Ability
- 25g
- Release date
- 2024-03-29