ChemicalBook > CAS DataBase List > (S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid

(S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid

Product Name
(S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid
CAS No.
70396-18-8
Chemical Name
(S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid
Synonyms
(tert-Butoxycarbonyl)-L-valyl-L-alanine;Boc-Val-Ala;Boc-L-Val-Ala-OH;Boc-L-Valyl- L-Alanin;N-Boc-L-valyl- L-alanine;(Tert-Butoxy)Carbonyl Val-Ala-OH;L-Alanine, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-;(S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid;(S)-2-((S)-2-((tert-Butoxycarbonyl)amino)-3-methylbutylamide)propionic acid;(2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]propanoic acid
CBNumber
CB92561447
Molecular Formula
C13H24N2O5
Formula Weight
288.34
MOL File
70396-18-8.mol
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(S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid Property

Boiling point:
493.3±30.0 °C(Predicted)
Density 
1.121±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
form 
Solid
pka
3.50±0.10(Predicted)
color 
White to off-white
InChI
InChI=1S/C13H24N2O5/c1-7(2)9(10(16)14-8(3)11(17)18)15-12(19)20-13(4,5)6/h7-9H,1-6H3,(H,14,16)(H,15,19)(H,17,18)/t8-,9-/m0/s1
InChIKey
FHBCSPANXVQYCP-IUCAKERBSA-N
SMILES
C(O)(=O)[C@H](C)NC(=O)[C@H](C(C)C)NC(OC(C)(C)C)=O
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific
Product number
4510CV
Product name
(S)-2-((S)-2-(Tert-butoxycarbonylamino)-3-methylbutanamido)propanoicacid
Packaging
1g
Price
$132
Updated
2021/12/16
Ambeed
Product number
A266251
Product name
Boc-Val-Ala-OH
Purity
95%
Packaging
5g
Price
$198
Updated
2021/12/16
Acrotein
Product number
NA-1269
Product name
N-Boc-L-valyl-L-alanine
Purity
97%
Packaging
5g
Price
$220
Updated
2021/12/16
Acrotein
Product number
NA-1269
Product name
N-Boc-L-valyl-L-alanine
Purity
97%
Packaging
25g
Price
$660
Updated
2021/12/16
Crysdot
Product number
CD22001871
Product name
Boc-Val-Ala-OH
Purity
95+%
Packaging
1g
Price
$923
Updated
2021/12/16
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(S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid Chemical Properties,Usage,Production

Description

Boc-Val-Ala-OH is a cleavable ADC linker. The Val-Ala is effectively cleaved by lysosomal proteolytic enzymes while being highly stable in human plasma, making this a potentent stragy in ADC linker design. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Uses

(tert-Butoxycarbonyl)-L-valyl-L-alanine is an alanine derivative[1].

References

[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1080. DOI:10.1080/10408398.2012.708368

(S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid Suppliers

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View Lastest Price from (S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid manufacturers

Shanghai Joiny Pharmaceutical Co.,LTD
Product
Boc-Val-Ala-OH 70396-18-8
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2025-05-08
Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Boc-Val-Ala 70396-18-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%+
Supply Ability
1T+
Release date
2024-04-10
Xian confluore Biological Technology Co., Ltd.
Product
Boc-Val-Ala-OH 70396-18-8
Price
US $0.00/g
Min. Order
25g
Purity
>95.00%
Supply Ability
25g
Release date
2024-03-29

70396-18-8, (S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acidRelated Search:

(2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid

  • (S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoic acid
  • (Tert-Butoxy)Carbonyl Val-Ala-OH
  • N-Boc-L-valyl- L-alanine
  • (2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]propanoic acid
  • (tert-Butoxycarbonyl)-L-valyl-L-alanine
  • L-Alanine, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-
  • Boc-Val-Ala
  • Boc-L-Valyl- L-Alanin
  • Boc-L-Val-Ala-OH
  • (S)-2-((S)-2-((tert-Butoxycarbonyl)amino)-3-methylbutylamide)propionic acid
  • 70396-18-8