OSW-1
- Product Name
- OSW-1
- CAS No.
- 145075-81-6
- Chemical Name
- OSW-1
- Synonyms
- OSW-1;Orsaponin;OSW-1 (Orsaponin);OSW-1, >90% (Orsaponin);16beta-[2-O-Acetyl-3-O-[2-O-(4-Methoxybenzoyl)-beta-D-xylopyranosyl)-alpha-L-arabinopyranosyloxy]-3b;(3β,16β)-16-[[2-O-Acetyl-3-O-[2-O-(4-methoxybenzoyl)-β-D-xylopyranosyl]-α-L-arabinopyranosyl]oxy]-3,17-dihydroxycholest-5-en-22-one;Cholest-5-en-22-one,16-[[2-O-acetyl-3-O-[2-O-(4-methoxybenzoyl)-b-D-xylopyranosyl]-a-L-arabinopyranosyl]oxy]-3,17-dihydroxy-, (3b,16b)-;Cholest-5-en-22-one, 16-[[2-O-acetyl-3-O-[2-O-(4-methoxybenzoyl)-β-D-xylopyranosyl]-α-L-arabinopyranosyl]oxy]-3,17-dihydroxy-, (3β,16β)-;16beta-[2-O-Acetyl-3-O-[2-O-(4-methoxybenzoyl)-beta-D-xylopyranosyl)-alpha-L-arabinopyranosyloxy]-3beta,17alpha-dihydroxycholest-5-en-22-one
- CBNumber
- CB8339904
- Molecular Formula
- C47H68O15
- Formula Weight
- 873.03
- MOL File
- 145075-81-6.mol
OSW-1 Property
- Boiling point:
- 932.5±65.0 °C(Predicted)
- Density
- 1.31±0.1 g/cm3(Predicted)
- storage temp.
- Hygroscopic, Refrigerator, under inert atmosphere
- solubility
- Chloroform (Slightly), Methanol (Slightly), Pyridine (Slightly)
- pka
- 12.65±0.70(Predicted)
- form
- Solid
- color
- White to Off-White
N-Bromosuccinimide Price
- Product number
- 30310
- Product name
- OSW-1
- Packaging
- 1mg
- Price
- $452
- Updated
- 2024/03/01
- Product number
- 30310
- Product name
- OSW-1
- Packaging
- 5mg
- Price
- $947
- Updated
- 2024/03/01
- Product number
- 30310
- Product name
- OSW-1
- Packaging
- 500μg
- Price
- $238
- Updated
- 2024/03/01
- Product number
- O703583
- Product name
- OSW-1,>90%(Orsaponin)
- Packaging
- 2.5mg
- Price
- $910
- Updated
- 2021/12/16
- Product number
- CHM1053098
- Product name
- OSW-1
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $801.71
- Updated
- 2021/12/16
OSW-1 Chemical Properties,Usage,Production
Description
OSW-1 is a saponin that has been found in O. saundersiae and has antiviral and anticancer activities. It is an inhibitor of oxysterol-binding protein (OSBP) and its paralog OSBP-related protein 4 (ORP4) with Ki values of 16 and 71 nM, respectively, in radioligand binding assays using HEK293T cell lysates. It induces OSBP translocalization from the cytoplasm to the trans-Golgi network and decreases intracellular levels of OSBP in HEK293 cells. OSW-1 inhibits replication of a variety of enteroviruses (IC50s = 2.4-9.4 nM), including replication of coxsackievirus B3 (CVB3) in infected HeLa R19 cells in an OSBP-dependent manner when used at a concentration of 3 nM. It also inhibits replication of hepatitis C virus (HCV) but not mouse hepatitis virus (MHV), a coronavirus. It protects against CVA9 and echovirus 2 infection in HeLa cells when used at a concentration of 10 nM. OSW-1 inhibits growth of HeLa and HEK293 cells (GI50s = 0.33 and 0.22 nM, respectively).
Uses
OSW-1 is a unique steroidal saponin displaying selective cytotoxicity against cancer cell lines. From Ornithogalum Saundersiae bulbs.
OSW-1 Preparation Products And Raw materials
Raw materials
Preparation Products
OSW-1 Suppliers
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 19892
- Advantage
- 58
- Tel
- +1-631-485-4226
- Fax
- 1-631-614-7828
- inquiry@bocsci.com
- Country
- United States
- ProdList
- 19553
- Advantage
- 58
View Lastest Price from OSW-1 manufacturers
- Product
- OSW-1 145075-81-6
- Price
- US $8.00/KG
- Min. Order
- 1g
- Purity
- Min98% HPLC/GC
- Supply Ability
- g/kg/ton
- Release date
- 2020-10-27