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TETRAGASTRIN

Product Name
TETRAGASTRIN
CAS No.
1947-37-1
Chemical Name
TETRAGASTRIN
Synonyms
TETRAGASTRIN;CCK-4 Acetate;Trp-Met-Asp-Phe amide;Cholecystokinin(36-39);Tetragastrin hydrochloride;H-Trp-Met-Asp-Phe-NH2 acetate;Cholecystokinin, CCK Tetrapeptide;4-7-Cholecystokinin-7 (swine) (9CI);CCK-4 Acetate, Gastrin Tetrapeptide;Cholecystokinin fragment 30-33 amide
CBNumber
CB8341406
Molecular Formula
C29H36N6O6S
Formula Weight
596.7
MOL File
1947-37-1.mol
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TETRAGASTRIN Property

Melting point:
185-195 °C
Boiling point:
1070.0±65.0 °C(Predicted)
Density 
1.348±0.06 g/cm3(Predicted)
storage temp. 
-20°C
form 
Solid
pka
4.19±0.10(Predicted)
color 
White to off-white
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Safety

WGK Germany 
3
Toxicity
dog,LD,intravenous,> 100mg/kg (100mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITINGGASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"BEHAVIORAL: EXCITEMENT,Oyo Yakuri. Pharmacometrics. Vol. 3, Pg. 121, 1969.
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T6515
Product name
Cholecystokinin Fragment 30-33 Amide
Purity
≥95% (HPLC)
Packaging
100mg
Price
$284
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
PEP0011758
Product name
TETRAGASTRIN
Purity
95.00%
Packaging
5MG
Price
$496.32
Updated
2021/12/16
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TETRAGASTRIN Chemical Properties,Usage,Production

Uses

Cholecystokinin Fragment 30-33 Amide can be used for inactivating the CCK8 antiserum. The product can also be used as an antigen utilized in absorption control for testing the specificity of antisera.

Definition

ChEBI: Tetragastrin is a tetrapeptide composed of L-tryptophan, L-methione, L-aspartic acid and L-phenylalaninamide residues joined in sequence. It has a role as an anxiogenic and a human metabolite. It is a tetrapeptide and a peptidyl amide.

Hazard

Moderately toxic by ingestion

Biochem/physiol Actions

Cholecystokinin Fragment 30-33 Amide also referred to as CCK-4 or Trp-Met-Asp-Phe amide is a peptide fragment derived from peptide hormone cholecystokinin. CCK-4 is a panicogenic agent that induces panic attacks in humans. This property of the compound can be used in scientific research for testing the new anxiolytic drugs.

TETRAGASTRIN Preparation Products And Raw materials

Raw materials

Preparation Products

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1947-37-1, TETRAGASTRINRelated Search:

Tetrapeptide-30 Tetrapeptide-16 Tetrapeptide-14 Tetrapeptide-21 PENTAGASTRIN Cholecystokinin Carbobenzoxy-D,L-tryptophanamide Z-TRP-NH2 Z-TRP-NHME TETRAGASTRIN

  • (3S)-3-[[(1S)-1-carbamoyl-2-phenyl-ethyl]carbamoyl]-3-[[(2S)-2-[[(2S)-3-(1H-indol-3-yl)-2-phenylmethoxycarbonylamino-propanoyl]amino]-4-methylsulfanyl-butanoyl]amino]propanoic acid
  • 4-7-Cholecystokinin-7 (swine) (9CI)
  • Alaninamide, L-tryptophyl-L-methionyl-L-aspartylphenyl- (7CI)
  • Alaninamide, L-tryptophyl-L-methionyl-L-aspartylphenyl-, L- (8CI)
  • Cholecystokinin C-terminal tetrapeptide
  • Cholecystokinin(36-39)
  • L-Phenylalaninamide, L-tryptophyl-L-methionyl-L-a-aspartyl-
  • Cholecystokinin fragment 30-33 amide
  • Cholecystokinin Tetrapeptide, Cholecystokinin Octapeptide (5-8), CCK-4, Gastrin (14-17) (huMan)
  • H-Trp-Met-Asp-Phe-NH2 acetate
  • Tetragastrin hydrochloride
  • Trp-Met-Asp-Phe amide
  • CCK-4 Acetate
  • Cholecystokinin, CCK Tetrapeptide
  • TETRAGASTRIN
  • CCK-4 Acetate, Gastrin Tetrapeptide
  • L-Phenylalaninamide, L-tryptophyl-L-methionyl-L-α-aspartyl-
  • Cholecystokinin Fragment 30-33 Amide >=95% (HPLC)
  • Gastrin Tetrapeptide H-Trp-Met-Asp-Phe-NH2
  • 1947-37-1