Z-SER(BZL)-OH

Product Name: Z-SER(BZL)-OH
CAS No.: 20806-43-3
Chemical Name: Z-SER(BZL)-OH
Synonyms: Z-SER(BZL)-OH;CBZ-SER(BZL)-OH;Z-L-Ser(Bzl)-OH;Z-SERINE(BZL)-OH;Cbz-L-Ser(Bzl)-OH;Z-Ser(Bzl)-OH,95 %;Z-O-BENZYL-L-SERINE;Cbz -O-benzyl-L-serine;Z-O-benzyl-L-serine99%;N-Cbz-O-Benzyl-L-Ser-OH
CBNumber: CB8346456
Molecular Formula: C18H19NO5
Formula Weight: 329.35
MOL File: 20806-43-3.mol

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Z-SER(BZL)-OH Property

Boiling point:: 537.1±50.0 °C(Predicted)
Density: 1.253±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Powder
pka: 3.51±0.10(Predicted)
color: White to off-white
optical activity: Consistent with structure
Water Solubility: Slightly soluble in water.
CAS DataBase Reference: 20806-43-3(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S776963
Product name: CARBOBENZYLOXY-O-BENZYL-L-SERINE
Purity: Aldrich<sup>CPR</sup>
Packaging: 1 unit
Price: $113
Updated: 2025/07/31

Sigma-Aldrich

Product number: S776963
Product name: CARBOBENZYLOXY-O-BENZYL-L-SERINE
Purity: AldrichCPR
Packaging: 50MG
Price: $110
Updated: 2024/03/01

Chem-Impex

Product number: 02252
Product name: Z-O-benzyl-L-serine,98.5%(HPLC)
Purity: 98.5%(HPLC)
Packaging: 1G
Price: $17.36
Updated: 2021/12/16

AK Scientific

Product number: E378
Product name: Cbz-Ser(bzl)-OH
Packaging: 5g
Price: $38
Updated: 2021/12/16

Activate Scientific

Product number: AS39016
Product name: Cbz-Ser(Bzl)-OH
Purity: 95% ee
Packaging: 5G
Price: $46
Updated: 2021/12/16

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Z-SER(BZL)-OH Chemical Properties,Usage,Production

Uses

Cbz-Ser(Bzl)-OH is used in preparation of Aminoamide derivatives as anticancer agents.

Synthesis

4726-96-9

31139-36-3

20806-43-3

At room temperature, O-benzyl-L-serine (25.0 g, 128 mmol) was dissolved in a mixed solvent of water (200 mL) and dioxane (100 mL) and sodium carbonate (7.46 g, 70 mmol) was added. Subsequently, a solution of dibenzyl dicarbonate (36.1 g, 126 mmol) in dioxane (100 mL) was slowly added dropwise and the reaction mixture was stirred at room temperature for 18 hours. Upon completion of the reaction, the dioxane was removed by vacuum evaporation and the remaining aqueous phase was extracted with ether. The organic phases were combined, dried over anhydrous sodium sulfate and concentrated under vacuum to give the crude product N-benzyloxycarbonyl-O-benzyl-L-serine (39.57 g, 95% yield) as a white solid, which was finally purified by washing with hexane.

References

[1] Liebigs Annalen der Chemie, 1994, # 6, p. 641 - 644
[2] Patent: US5030654, 1991, A
[3] Patent: EP274234, 1991, B1

Z-SER(BZL)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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Z-SER(BZL)-OH Suppliers

China 118 Germany 4 Hungary 1 India 4 Japan 3 South Korea 1 Switzerland 1 United Kingdom 3 United States 16 Global 151

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
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GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
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Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
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Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
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Chemsky (shanghai) International Co.,Ltd

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Email: shchemsky@sina.com
Country: China
ProdList: 15402
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Shandong Xiya Chemical Co., Ltd

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China Langchem Inc.

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Country: China
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ChemPep, Inc.

Tel: +1 (888) 615-9178 / (561) 791-8787
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Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
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Beijing HuaMeiHuLiBiological Chemical

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Email: waley188@sohu.com
Country: China
ProdList: 12335
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View Lastest Price from Z-SER(BZL)-OH manufacturers

Career Henan Chemical Co

Product: Z-SER(BZL)-OH 20806-43-3
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2020-01-30

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20806-43-3