Z-TRP-OBZL

Product Name: Z-TRP-OBZL
CAS No.: 69876-37-5
Chemical Name: Z-TRP-OBZL
Synonyms: Z-TRP-OBZL;Cbz-Trp-OBzl;Z-L-Trp-OBzl;Z-L-TRYPTOPHAN BENZYL ESTER;N-a-Z-L-tryptophanbenzylester;Nα-Z-L-tryptophan benzyl ester;N-α-Z-L-tryptophan benzyl ester;N-cbz-L-tryptophan benzyl ester;N-.ALPHA.-CBZ-L-TRYPTOPHAN BENZYL ESTER;N-Carbobenzyloxy-L-tryptphan benzyl ester
CBNumber: CB3358438
Molecular Formula: C26H24N2O4
Formula Weight: 428.48
MOL File: 69876-37-5.mol

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Z-TRP-OBZL Property

Melting point:: 105-108℃
Boiling point:: 656.7±55.0 °C(Predicted)
Density: 1.266±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
form: Powder
pka: 10.93±0.46(Predicted)
color: White to off-white
optical activity: 7.70°(C=0.01g/mL, CHCL3, 20°C, 589nm)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific

Product number: V0756
Product name: Z-Trp-OBzl
Packaging: 1g
Price: $14
Updated: 2021/12/16

Chem-Impex

Product number: 06627
Product name: Z-L-tryptophan benzyl ester
Purity: ≥ 99% (HPLC)
Packaging: 1G
Price: $25.9
Updated: 2021/12/16

AK Scientific

Product number: V0756
Product name: Z-Trp-OBzl
Packaging: 5g
Price: $54
Updated: 2021/12/16

Activate Scientific

Product number: AS91250
Product name: Nalpha-Cbz-L-tryptophan Benzyl Ester
Purity: 97+% ee
Packaging: 5G
Price: $86
Updated: 2021/12/16

ChemPep

Product number: 411802
Product name: Z-Trp-OBzl
Purity: ≥98%
Packaging: 1g
Price: $98
Updated: 2021/12/16

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Z-TRP-OBZL Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Synthesis

100-51-6

7432-21-5

69876-37-5

GENERAL STEPS: To a stirred suspension of (S)-2-(((benzyloxy)carbonyl)amino)-3-(1H-indol-3-yl)propanoic acid (2.45 g, 7.2 mmol) in 10 mL of anhydrous dichloromethane, 4-dimethylaminopyridine (DMAP, 88 mg, 0.72 mmol) and benzyl alcohol (1.28 g, 11.8 mmol) were added. A 5 mL solution of N,N'-dicyclohexylcarbodiimide (DCC, 1.48 g, 7.2 mmol) in dichloromethane was slowly added at 0 °C. The reaction was carried out at 0 °C with the addition of N,N'-dicyclohexylcarbodiimide (DCC, 1.48 g, 7.2 mmol). The reaction mixture was slowly warmed to room temperature and stirred overnight. The white precipitate was removed by filtration and the solvent was subsequently removed by distillation under reduced pressure to afford the colorless oily product Cbz-L-tryptophan benzyl ester (3 g, 98%). The product had a rotativity of [α]D20 = +50 (c = 1.0, CHCl3, 365 nm). Thin layer chromatography (TLC) showed Rf = 0.29 (ethyl acetate:hexane = 1:2).1H NMR (400 MHz, CDCl3) δ: 8.26 (br, 1H), 7.56 (d, J = 8.0 Hz, 1H), 7.41-7.33 (m, 9H), 7.26-7.20 (m, 3H), 7.12 (t, J = 8.0 Hz , 1H), 6.76 (d, J = 2.0 Hz, 1H), 5.47 (d, J = 8.0 Hz, 1H), 5.18-5.10 (m, 4H), 4.82 (q, J = 8.0 Hz, 1H), 3.34 (d, J = 5.1 Hz, 2H).13C NMR (100 MHz, CDCl3) δ: 171.8, 155.8 , 136.1, 136.0, 135.1, 128.5, 128.4, 128.3, 128.0, 127.5, 127.4, 126.9, 122.9, 122.0, 119.5, 118.5, 111.2, 109.4, 67.1, 66.8, 54.6, 27.8.Fourier transform infrared (FTIR) spectroscopy ( FTIR, pure sample) showed absorption peaks located at 3395, 3343, 1742, 1458, 1377, 721 cm-1. High resolution mass spectrometry (HRMS, ESI) calculated value of C20H20O4N2 [M + H]+ was 429.1814 and measured value was 429.1821.

References

[1] Patent: US2011/269972, 2011, A1. Location in patent: Page/Page column 20

Z-TRP-OBZL Preparation Products And Raw materials

Raw materials

Preparation Products

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Z-TRP-OBZL Suppliers

China 79 Germany 2 India 2 Japan 1 Switzerland 1 United Kingdom 3 United States 8 Global 96

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

ChemPep, Inc.

Tel: +1 (888) 615-9178 / (561) 791-8787
Fax: +1 (561) 791-8728
Email: service@chempep.com
Country: United States
ProdList: 2138
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Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12335
Advantage: 58

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
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Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
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Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
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Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9637
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NINGBO INNO PHARMCHEM CO.,LTD.

Tel: 86-574-27787657
Fax: 86-574-27912196
Email: info@dearchem.com
Country: China
ProdList: 4613
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View Lastest Price from Z-TRP-OBZL manufacturers

Career Henan Chemical Co

Product: Z-TRP-OBZL 69876-37-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2018-08-09

Career Henan Chemical Co

Product: Z-TRP-OBZL 69876-37-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20kg
Release date: 2018-08-15

69876-37-5, Z-TRP-OBZLRelated Search:

N-Cbz-L-Tryptophan Z-TRP-NH2 Z-TRP-OME Z-VAL-TRP-OH Z-TRP-OSU Z-TRP(BOC)-OH DCHA Z-PHE-ALA-OH Z-TRP-TRP-OH Z-PHE-TRP-OH Z-SER-NHNH2 Z-TRP-ONP Z-TRP(FOR)-OH Z-Trp(For)-OH.DCHA Z-Trp-Lys(Boc)-NH2 tert-butyl N-[(5S)-6-amino-5-[[(2S)-3-(1H-indol-3-yl)-2-(phenylmethoxycarbonylamino)propanoyl]amino]-6-oxohexyl]carbamate N-Cbz-O-tert-butyl-L-serine Z-TYR(TBU)-OH Z-LYS-SBZL HCL

N-.ALPHA.-CBZ-L-TRYPTOPHAN BENZYL ESTER

N-Carbobenzyloxy-L-tryptphan benzyl ester

(S)-benzyl 2-(benzyloxycarbonylamino)-3-(1H-indol-3-yl)propanoate

Benzyl (S)-2-(benzyloxycarbonylamino)-3-(1H-indol-3-yl)propanoate

N-[(Phenylmethoxy)carbonyl]-L-tryptophan phenylmethyl ester

N-ALPHA-CARBOBENZOXY-L-TRYPTOPHAN ALPHA-BENZYL ESTER

Z-L-TRYPTOPHAN BENZYL ESTER

Z-TRP-OBZL

Cbz-Trp-OBzl

N-α-Z-L-tryptophan benzyl ester

N-a-Z-L-tryptophanbenzylester

Nα-Z-L-tryptophan benzyl ester≥ 99% (HPLC)

Z-L-Trp-OBzl

N-Benzyloxycarbonyl-L-tryptophan benzyl ester

benzyl (2S)-2-{[(benzyloxy)carbonyl]amino}-3-(1H-indol-3-yl)propanoate

L-Tryptophan, N-[(phenylmethoxy)carbonyl]-, phenylmethyl ester

Nα-Z-L-tryptophan benzyl ester

benzyl (2S)-2-(benzyloxycarbonylamino)-3-(1H-indol-3-yl)prop...

N-cbz-L-tryptophan benzyl ester

Benzyl N-[(benzyloxy)carbonyl]-L-tryptophanate

69876-37-5

C26H24N2O4

Tryptophan [Trp, W]

Z-Amino Acids and Derivatives

Z-Amino acid series