Z-TRP-OME

Product Name: Z-TRP-OME
CAS No.: 2717-76-2
Chemical Name: Z-TRP-OME
Synonyms: Z-TRP-OME;Cbz-L-Trp-OMe;Z-TRP-OME USP/EP/BP;Cbz-L-Tryptophan-methyl ester;Z-L-tryptophan beta-Methyl ester;N-Carbobenzoxy-L-tryptophan methyl ester;Methyl ((benzyloxy)carbonyl)-L-tryptophanate;L-Tryptophan, N-[(phenylmethoxy)carbonyl]-, methyl ester;(S)-methyl 2-(benzyloxycarbonylamino)-3-(1H-indol-3-yl)propanoate;methyl (2S)-2-{[(benzyloxy)carbonyl]amino}-3-(1H-indol-3-yl)propanoate
CBNumber: CB5713572
Molecular Formula: C20H20N2O4
Formula Weight: 352.38
MOL File: 2717-76-2.mol

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Z-TRP-OME Property

Boiling point:: 579.3±50.0 °C(Predicted)
Density: 1.269±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 10.95±0.46(Predicted)
Appearance: Off-white to yellow Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific

Product number: 0581AP
Product name: Z-Trp-Ome
Packaging: 10g
Price: $151
Updated: 2021/12/16

chempep

Product number: 411803
Product name: Z-Trp-OMe
Purity: >=98%
Packaging: 25g
Price: $228
Updated: 2021/12/16

ChemPep

Product number: 411803
Product name: Z-Trp-OMe
Purity: ≥98%
Packaging: 100g
Price: $535
Updated: 2021/12/16

Ambeed

Product number: A367173
Product name: Z-Trp-OMe
Purity: 95%
Packaging: 250mg
Price: $7
Updated: 2021/12/16

Ambeed

Product number: A367173
Product name: Z-Trp-OMe
Purity: 95%
Packaging: 1g
Price: $9
Updated: 2021/12/16

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Z-TRP-OME Chemical Properties,Usage,Production

Synthesis

67-56-1

7432-21-5

2717-76-2

Under nitrogen protection, (S)-N-benzyloxycarbonyl-L-tryptophan (2.45 g, 7.2 mmol) was suspended in 10 mL of anhydrous dichloromethane and 4-dimethylaminopyridine (DMAP, 0.1 g, 0.82 mmol) and methanol (0.28 g, 11.8 mmol) were added. The reaction mixture was cooled to 0 °C and a solution of N,N'-dicyclohexylcarbodiimide (DCC) dissolved in dichloromethane was slowly added dropwise. After the dropwise addition, the reaction system was gradually warmed up to room temperature and stirred continuously for 12 hours. After completion of the reaction, the insoluble material was removed by filtration and the filtrate was concentrated under reduced pressure. The crude product was purified by fast column chromatography (eluent: n-hexane/ethyl acetate, 4:1 to 2:1 gradient elution) to afford the target compound (S)-methyl (S)-2-(((benzyloxy)carbonyl)amino)-3-(1H-indol-3-yl)propanoate (2.5 g, 98%) as a colorless oil. Thin layer chromatography (TLC) Rf = 0.19 (Expanding agent: ethyl acetate/hexane = 1:2). Nuclear magnetic resonance hydrogen spectrum (1H NMR, 300 MHz, CDCl3): δ 8.94 (broad peak, 1H), 7.49 (d, J = 7.7 Hz, 1H), 7.25-6.98 (multiple peaks, 9H), 6.81 (single peak, 1H), 5.84 (d, J = 8.7 Hz, 1H), 4.98 (d, J = 3.2 Hz, 2H), 4.68 (quadruple peak, 2H). 4.68 (quadruple peak, J = 7.3 Hz, 1H), 3.25 (single peak, 3H), 3.21 (multiple peaks, 2H). Nuclear magnetic resonance carbon spectrum (13C NMR, 75 MHz, CDCl3): δ 172.2, 155.9, 141.8, 136.8, 134.9, 128.6, 127.8, 126.9, 123.4, 122.3, 120.0, 118.4, 112.1, 109.4, 67.0, 65.1, 55.1. Fourier Transform Infrared Spectroscopy (FTIR, KBr, pure sample): ν 1707, 1508, 1456, 1436, 1215, 742 cm-1. High Resolution Mass Spectrometry (HRMS, EI): Calculated value C20H20O4N2 [M]+ 352.1418, measured value 352.1425.

References

[1] Organic and Biomolecular Chemistry, 2003, vol. 1, # 20, p. 3492 - 3494
[2] Advanced Synthesis and Catalysis, 2010, vol. 352, # 7, p. 1107 - 1112
[3] Patent: US2011/269972, 2011, A1. Location in patent: Page/Page column 18-19

Z-TRP-OME Preparation Products And Raw materials

Raw materials

Preparation Products

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Z-TRP-OME Suppliers

China 57 Germany 1 India 1 United Kingdom 2 United States 5 Global 66

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

ChemPep, Inc.

Tel: +1 (888) 615-9178 / (561) 791-8787
Fax: +1 (561) 791-8728
Email: service@chempep.com
Country: United States
ProdList: 2138
Advantage: 57

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

NINGBO INNO PHARMCHEM CO.,LTD.

Tel: 86-574-27787657
Fax: 86-574-27912196
Email: info@dearchem.com
Country: China
ProdList: 4613
Advantage: 58

Zhengzhou Alfachem Co., Ltd.

Tel: 0371-53765687 18937137882
Fax: QQ:2885373884
Email: 2853979813@qq.com
Country: China
ProdList: 7992
Advantage: 55

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 6687
Advantage: 55

Shanghai GL Peptide Ltd.

Tel: +86-21-61263340; 17609490614 13764994101
Fax: 021-61263399
Email: fisherwang@glschina.com
Country: China
ProdList: 8258
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Wuxi Asia Peptide Biotechnology Limited Company

Tel: 0510-83583050 13771062561
Fax: 0510-83583039
Email: willsun@peptide-search.com
Country: China
ProdList: 6716
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Nanjing Peptide Biotech Ltd.

Tel: 025-58361106-805 15951641583
Fax: 025-58361106-806
Email: zhao.xu@njpeptide.com
Country: China
ProdList: 9979
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View Lastest Price from Z-TRP-OME manufacturers

Sichuan Jiaying Lai Technology Co.,LTD

Product: Cbz-L-Trp-ome 2717-76-2
Price: US $1.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 100KG
Release date: 2019-07-22

2717-76-2, Z-TRP-OMERelated Search:

N-Cbz-L-Tryptophan Z-Trp-OEt Z-TRP-OBZL Z-TRP-ONP Z-SER(TOS)-OME Z-ORN(BOC)-OH DCHA Z-ILE-OSU Z-ORN(FMOC)-OH Z-VAL-OET Z-TRP(BOC)-OH DCHA Z-TYR-OH Z-VAL-OSU Z-VAL-NH2 Z-VAL-PHE-OME Z-TLE-OH DCHA Z-TYR(TBU)-OSU Z-TYR-ONP Z-TYR-OME

Z-TRP-OME

(S)-methyl 2-(benzyloxycarbonylamino)-3-(1H-indol-3-yl)propanoate

Cbz-L-Tryptophan-methyl ester

Z-L-tryptophan beta-Methyl ester

N-Carbobenzoxy-L-tryptophan methyl ester

Cbz-L-Trp-OMe

methyl (2S)-2-{[(benzyloxy)carbonyl]amino}-3-(1H-indol-3-yl)propanoate

L-Tryptophan, N-[(phenylmethoxy)carbonyl]-, methyl ester

Z-TRP-OME USP/EP/BP

Methyl ((benzyloxy)carbonyl)-L-tryptophanate

2717-76-2

Z-Amino Acids and Derivatives

Z-Amino acid series