Z-VAL-OSU
- Product Name
- Z-VAL-OSU
- CAS No.
- 3496-11-5
- Chemical Name
- Z-VAL-OSU
- Synonyms
- Z-VAL-OSU;3496/11/5;NSC 322480;Z-L-Val-OSu;CBZ-Val-Osu;Z-VALINE-OSU;Z-L-Val-ONSu;CBZ-L-VALINE-OSU;Z-VAL-OSU USP/EP/BP;Z-L-VALINE HYDROXYSUCCINIMIDESTER
- CBNumber
- CB1233469
- Molecular Formula
- C17H20N2O6
- Formula Weight
- 348.35
- MOL File
- 3496-11-5.mol
Z-VAL-OSU Property
- Melting point:
- 114-118℃
- Density
- 1.30±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- Soluble in 1mmol in 2mL DCM.
- pka
- 10.51±0.46(Predicted)
- form
- Powder
- color
- White to off-white
- optical activity
- -21.534°(C=0.01 g/ml Dioxane)
- CAS DataBase Reference
- 3496-11-5
Safety
- HS Code
- 2933.79.8500
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- S790613
- Product name
- CARBOBENZYLOXY-L-VALINE N-HYDROXYSUCCINIMIDE ESTER
- Purity
- Aldrich<sup>CPR</sup>
- Packaging
- 1 unit
- Price
- $113
- Updated
- 2025/07/31
- Product number
- S790613
- Product name
- CARBOBENZYLOXY-L-VALINE N-HYDROXYSUCCINIMIDE ESTER
- Purity
- AldrichCPR
- Packaging
- 250MG
- Price
- $110
- Updated
- 2024/03/01
- Product number
- C2334
- Product name
- N-Carbobenzoxy-L-valine Succinimidyl Ester
- Purity
- >98.0%(HPLC)
- Packaging
- 5g
- Price
- $38
- Updated
- 2025/07/31
- Product number
- 291993
- Product name
- Z-L-valine N-hydroxysuccinimide ester
- Packaging
- 10g
- Price
- $333
- Updated
- 2021/12/16
- Product number
- C178265
- Product name
- N-Carbobenzoxy-L-valine Succinimidyl Ester
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
Z-VAL-OSU Chemical Properties,Usage,Production
Chemical Properties
White to off- white powder
Uses
N-Benzyloxycarbonyl-L-valine N-succinimidyl ester, is an amino acid which is widely used in pharmaceutical and food industry.
Synthesis
6066-82-6
1149-26-4
3496-11-5
Step 1. To a stirred solution of N-hydroxybutanediimide (1 g, 4 mmol) and CBZ-L-valine (459 mg, 4 mmol) in tetrahydrofuran (THF, 20 mL) was added N,N'-dicyclohexylcarbodiimide (DCC, 908 mg, 4.4 mmol) at 0° C. The reaction was carried out at room temperature. The reaction mixture was stirred at room temperature for 16 hours. After completion of the reaction, the mixture was filtered and the filtrate was concentrated to afford (S)-2,5-dioxopyrrolidin-1-yl 2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate (yield: 90%).
References
[1] Chemical Communications, 2015, vol. 51, # 67, p. 13213 - 13216
[2] Organic and Biomolecular Chemistry, 2015, vol. 13, # 28, p. 7736 - 7749
[3] Patent: WO2015/95227, 2015, A2. Location in patent: Page/Page column 133
[4] Journal of Medicinal Chemistry, 2018, vol. 61, # 3, p. 989 - 1000
[5] Journal of the American Chemical Society, 2003, vol. 125, # 22, p. 6677 - 6686
Z-VAL-OSU Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Z-VAL-OSU manufacturers
- Product
- N-Carbobenzoxy-L-valine SucciniMidyl Ester 3496-11-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 20T
- Release date
- 2024-07-10
- Product
- Z-VAL-OSU 3496-11-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2018-08-09