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Z-VAL-OSU

Product Name
Z-VAL-OSU
CAS No.
3496-11-5
Chemical Name
Z-VAL-OSU
Synonyms
Z-VAL-OSU;3496/11/5;NSC 322480;Z-L-Val-OSu;CBZ-Val-Osu;Z-VALINE-OSU;Z-L-Val-ONSu;CBZ-L-VALINE-OSU;Z-VAL-OSU USP/EP/BP;Z-L-VALINE HYDROXYSUCCINIMIDESTER
CBNumber
CB1233469
Molecular Formula
C17H20N2O6
Formula Weight
348.35
MOL File
3496-11-5.mol
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Z-VAL-OSU Property

Melting point:
114-118℃
Density 
1.30±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,2-8°C
solubility 
Soluble in 1mmol in 2mL DCM.
pka
10.51±0.46(Predicted)
form 
Powder
color 
White to off-white
optical activity
-21.534°(C=0.01 g/ml Dioxane)
CAS DataBase Reference
3496-11-5
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Safety

HS Code 
2933.79.8500
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S790613
Product name
CARBOBENZYLOXY-L-VALINE N-HYDROXYSUCCINIMIDE ESTER
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$113
Updated
2025/07/31
Sigma-Aldrich
Product number
S790613
Product name
CARBOBENZYLOXY-L-VALINE N-HYDROXYSUCCINIMIDE ESTER
Purity
AldrichCPR
Packaging
250MG
Price
$110
Updated
2024/03/01
TCI Chemical
Product number
C2334
Product name
N-Carbobenzoxy-L-valine Succinimidyl Ester
Purity
>98.0%(HPLC)
Packaging
5g
Price
$38
Updated
2025/07/31
Usbiological
Product number
291993
Product name
Z-L-valine N-hydroxysuccinimide ester
Packaging
10g
Price
$333
Updated
2021/12/16
TRC
Product number
C178265
Product name
N-Carbobenzoxy-L-valine Succinimidyl Ester
Packaging
50mg
Price
$45
Updated
2021/12/16
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Z-VAL-OSU Chemical Properties,Usage,Production

Chemical Properties

White to off- white powder

Uses

N-Benzyloxycarbonyl-L-valine N-succinimidyl ester, is an amino acid which is widely used in pharmaceutical and food industry.

Synthesis

6066-82-6

1149-26-4

3496-11-5

Step 1. To a stirred solution of N-hydroxybutanediimide (1 g, 4 mmol) and CBZ-L-valine (459 mg, 4 mmol) in tetrahydrofuran (THF, 20 mL) was added N,N'-dicyclohexylcarbodiimide (DCC, 908 mg, 4.4 mmol) at 0° C. The reaction was carried out at room temperature. The reaction mixture was stirred at room temperature for 16 hours. After completion of the reaction, the mixture was filtered and the filtrate was concentrated to afford (S)-2,5-dioxopyrrolidin-1-yl 2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate (yield: 90%).

References

[1] Chemical Communications, 2015, vol. 51, # 67, p. 13213 - 13216
[2] Organic and Biomolecular Chemistry, 2015, vol. 13, # 28, p. 7736 - 7749
[3] Patent: WO2015/95227, 2015, A2. Location in patent: Page/Page column 133
[4] Journal of Medicinal Chemistry, 2018, vol. 61, # 3, p. 989 - 1000
[5] Journal of the American Chemical Society, 2003, vol. 125, # 22, p. 6677 - 6686

Z-VAL-OSU Preparation Products And Raw materials

Raw materials

Preparation Products

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Z-VAL-OSU Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9883
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11705
Advantage
57
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View Lastest Price from Z-VAL-OSU manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
N-Carbobenzoxy-L-valine SucciniMidyl Ester 3496-11-5
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
20T
Release date
2024-07-10
Career Henan Chemical Co
Product
Z-VAL-OSU 3496-11-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1ton
Release date
2018-08-09

3496-11-5, Z-VAL-OSURelated Search:


  • Z-VALINE-OSU
  • Z-VAL-OSU
  • Z-L-VALINE HYDROXYSUCCINIMIDE ESTER
  • Z-L-VALINE N-HYDROXYSUCCINIMIDE ESTER
  • 2,5-dioxopyrrolidin-1-yl (2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanoate
  • phenyl N-[(3S)-1-(2,5-dioxopyrrolidin-1-yl)-4-methyl-2-oxopentan-3-yl]carbamate
  • (2,5-dioxopyrrolidin-1-yl) (2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoate
  • N-CARBOBENZOXY-L-VALINE-N-HYDROXYSUCCINIMIDE ESTER
  • N-ALPHA-CBZ-L-VALINE N-HYDROXYSUCCINIMIDE ESTER
  • BENZYLOXYCARBONYL-L-VALINE N-HYDROXYSUCCINIMIDE ESTER
  • CBZ-L-VALINE HYDROXYSUCCINIMIDE ESTER
  • benzyl (S)-[1-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-2-methylpropyl]carbamate
  • CBZ-L-VALINE-OSU
  • Z-VALINE 1-HYDROXYSUCCINIMDE ESTER
  • N-alpha-Benzyloxycarbonyl-L-valine succinimidyl ester
  • Z-L-Val-OSu
  • Z-L-VALINE HYDROXYSUCCINIMIDESTER
  • CBZ-L-VALINE N-HYDROXYSUCCINIMIDE ESTER
  • [(S)-1-[[(2,5-Dioxo-1-pyrrolidinyl)oxy]carbonyl]-2-methylpropyl]carbamic acid benzyl ester
  • N-(Benzyloxycarbonyl)-L-valine succinimidyl ester
  • Z-L-Val-ONSu
  • N-Carbobenzoxy-L-valine Succinimidyl Ester
  • (2,5-dioxopyrrolidin-1-yl) 3-methyl-2-(phenylmethoxycarbonylamino)butanoate
  • 2-(benzyloxycarbonylamino)-3-methyl-butyric acid succinimido ester
  • CBZ-Val-Osu
  • N-Cbz-L-valine Succinimidyl Ester Z-Val-OSu
  • N-Benzoxycarbonyl-L-valine N-succiniMidyl ester, 98%
  • (S)-2,5-Dioxopyrrolidin-1-yl 2-(((benzyloxy)carbonyl)aMino)-3-Methylbutanoate
  • L-Valine,N-[(phenylmethoxy)carbonyl]-, 2,5-dioxo-1-pyrrolidinyl ester
  • 3496/11/5
  • N-Cbz-L-valine Succinimidyl Ester
  • N-Benzyloxycarbonyl-L-valine N-succinimidyl ester
  • Z-L-valineN-hydroxysuccinimide ester≥ 98% (HPLC)
  • N-Carbobenzoxy-L-valine Succinimidyl Ester &gt
  • Z-VAL-OSU USP/EP/BP
  • NSC 322480
  • Fluvastatin Impurity 6 Sodium Salt(Fluvastatin EP Impurity F Sodium Salt)
  • CARBOBENZYLOXY-L-VALINE N-HYDROXYSUCCINIMIDE ESTER
  • N-Benzoxycarbonyl-L-valine N-succiniMidyl ester
  • 3496-11-5
  • 583238
  • Z-Amino Acids and Derivatives
  • Z-Amino acid series
  • Amino Acid Derivatives