ChemicalBook > CAS DataBase List > Z-VAL-OSU

Z-VAL-OSU

Product Name
Z-VAL-OSU
CAS No.
3496-11-5
Chemical Name
Z-VAL-OSU
Synonyms
Z-VAL-OSU;3496/11/5;NSC 322480;Z-L-Val-OSu;CBZ-Val-Osu;Z-VALINE-OSU;Z-L-Val-ONSu;CBZ-L-VALINE-OSU;Z-VAL-OSU USP/EP/BP;Z-L-VALINE HYDROXYSUCCINIMIDESTER
CBNumber
CB1233469
Molecular Formula
C17H20N2O6
Formula Weight
348.35
MOL File
3496-11-5.mol
More
Less

Z-VAL-OSU Property

Melting point:
114-118℃
Density 
1.30±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,2-8°C
solubility 
Soluble in 1mmol in 2mL DCM.
pka
10.51±0.46(Predicted)
form 
Powder
color 
White to off-white
optical activity
-21.534°(C=0.01 g/ml Dioxane)
CAS DataBase Reference
3496-11-5
More
Less

Safety

HS Code 
2933.79.8500
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S790613
Product name
CARBOBENZYLOXY-L-VALINE N-HYDROXYSUCCINIMIDE ESTER
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$113
Updated
2025/07/31
Sigma-Aldrich
Product number
S790613
Product name
CARBOBENZYLOXY-L-VALINE N-HYDROXYSUCCINIMIDE ESTER
Purity
AldrichCPR
Packaging
250MG
Price
$110
Updated
2024/03/01
TCI Chemical
Product number
C2334
Product name
N-Carbobenzoxy-L-valine Succinimidyl Ester
Purity
>98.0%(HPLC)
Packaging
5g
Price
$38
Updated
2025/07/31
Usbiological
Product number
291993
Product name
Z-L-valine N-hydroxysuccinimide ester
Packaging
10g
Price
$333
Updated
2021/12/16
TRC
Product number
C178265
Product name
N-Carbobenzoxy-L-valine Succinimidyl Ester
Packaging
50mg
Price
$45
Updated
2021/12/16
More
Less

Z-VAL-OSU Chemical Properties,Usage,Production

Chemical Properties

White to off- white powder

Uses

N-Benzyloxycarbonyl-L-valine N-succinimidyl ester, is an amino acid which is widely used in pharmaceutical and food industry.

Synthesis

6066-82-6

1149-26-4

3496-11-5

Step 1. To a stirred solution of N-hydroxybutanediimide (1 g, 4 mmol) and CBZ-L-valine (459 mg, 4 mmol) in tetrahydrofuran (THF, 20 mL) was added N,N'-dicyclohexylcarbodiimide (DCC, 908 mg, 4.4 mmol) at 0° C. The reaction was carried out at room temperature. The reaction mixture was stirred at room temperature for 16 hours. After completion of the reaction, the mixture was filtered and the filtrate was concentrated to afford (S)-2,5-dioxopyrrolidin-1-yl 2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate (yield: 90%).

References

[1] Chemical Communications, 2015, vol. 51, # 67, p. 13213 - 13216
[2] Organic and Biomolecular Chemistry, 2015, vol. 13, # 28, p. 7736 - 7749
[3] Patent: WO2015/95227, 2015, A2. Location in patent: Page/Page column 133
[4] Journal of Medicinal Chemistry, 2018, vol. 61, # 3, p. 989 - 1000
[5] Journal of the American Chemical Society, 2003, vol. 125, # 22, p. 6677 - 6686

Z-VAL-OSU Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Z-VAL-OSU Suppliers

Americas 1 China 107 Europe 1 Germany 2 India 2 Japan 2 Switzerland 1 United Kingdom 4 United States 17 Global 137
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
More
Less

View Lastest Price from Z-VAL-OSU manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
N-Carbobenzoxy-L-valine SucciniMidyl Ester 3496-11-5
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
20T
Release date
2024-07-10
Career Henan Chemical Co
Product
Z-VAL-OSU 3496-11-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1ton
Release date
2018-08-09

3496-11-5, Z-VAL-OSURelated Search:

N-Carbobenzyloxy-L-valine Z-VAL-OET CBZ-L-VALINE METHYL ESTER Z-VAL-GLY-OH Z-VAL-ALA-OH Z-VAL-ONP Z-VAL-NH2 Z-VAL-PRO-OH Z-VAL-PHE-OH Z-TYR-OH Z-VAL-PHE-OME Z-TLE-OH DCHA Z-TRP-OME Z-TYR(TBU)-OSU Z-TYR-ONP Z-TYR-OME Zuclopenthixol Z-L-Valine NCA

  • Z-VALINE-OSU
  • Z-VAL-OSU
  • Z-L-VALINE HYDROXYSUCCINIMIDE ESTER
  • Z-L-VALINE N-HYDROXYSUCCINIMIDE ESTER
  • 2,5-dioxopyrrolidin-1-yl (2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanoate
  • phenyl N-[(3S)-1-(2,5-dioxopyrrolidin-1-yl)-4-methyl-2-oxopentan-3-yl]carbamate
  • (2,5-dioxopyrrolidin-1-yl) (2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoate
  • N-CARBOBENZOXY-L-VALINE-N-HYDROXYSUCCINIMIDE ESTER
  • N-ALPHA-CBZ-L-VALINE N-HYDROXYSUCCINIMIDE ESTER
  • BENZYLOXYCARBONYL-L-VALINE N-HYDROXYSUCCINIMIDE ESTER
  • CBZ-L-VALINE HYDROXYSUCCINIMIDE ESTER
  • benzyl (S)-[1-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-2-methylpropyl]carbamate
  • CBZ-L-VALINE-OSU
  • Z-VALINE 1-HYDROXYSUCCINIMDE ESTER
  • N-alpha-Benzyloxycarbonyl-L-valine succinimidyl ester
  • Z-L-Val-OSu
  • Z-L-VALINE HYDROXYSUCCINIMIDESTER
  • CBZ-L-VALINE N-HYDROXYSUCCINIMIDE ESTER
  • [(S)-1-[[(2,5-Dioxo-1-pyrrolidinyl)oxy]carbonyl]-2-methylpropyl]carbamic acid benzyl ester
  • N-(Benzyloxycarbonyl)-L-valine succinimidyl ester
  • Z-L-Val-ONSu
  • N-Carbobenzoxy-L-valine Succinimidyl Ester
  • (2,5-dioxopyrrolidin-1-yl) 3-methyl-2-(phenylmethoxycarbonylamino)butanoate
  • 2-(benzyloxycarbonylamino)-3-methyl-butyric acid succinimido ester
  • CBZ-Val-Osu
  • N-Cbz-L-valine Succinimidyl Ester Z-Val-OSu
  • N-Benzoxycarbonyl-L-valine N-succiniMidyl ester, 98%
  • (S)-2,5-Dioxopyrrolidin-1-yl 2-(((benzyloxy)carbonyl)aMino)-3-Methylbutanoate
  • L-Valine,N-[(phenylmethoxy)carbonyl]-, 2,5-dioxo-1-pyrrolidinyl ester
  • 3496/11/5
  • N-Cbz-L-valine Succinimidyl Ester
  • N-Benzyloxycarbonyl-L-valine N-succinimidyl ester
  • Z-L-valineN-hydroxysuccinimide ester≥ 98% (HPLC)
  • N-Carbobenzoxy-L-valine Succinimidyl Ester &gt
  • Z-VAL-OSU USP/EP/BP
  • NSC 322480
  • Fluvastatin Impurity 6 Sodium Salt(Fluvastatin EP Impurity F Sodium Salt)
  • CARBOBENZYLOXY-L-VALINE N-HYDROXYSUCCINIMIDE ESTER
  • N-Benzoxycarbonyl-L-valine N-succiniMidyl ester
  • 3496-11-5
  • 583238
  • Z-Amino Acids and Derivatives
  • Z-Amino acid series
  • Amino Acid Derivatives