7-Chloro-2-methylquinoline

Product Name: 7-Chloro-2-methylquinoline
CAS No.: 4965-33-7
Chemical Name: 7-Chloro-2-methylquinoline
Synonyms: 7-CHLOROQUINALDINE;2-METHYL-7-CHLOROQUINOLINE;Chloroquinaldine;Chloroquinaldine,98%;7-Chloro-2-methylqui;7-Chloroquildine, 99%;7-Chloroquinaldine>7-CHLOROQUINALDINE 99%;7-chloroquine pyridine;7-ChloroQuinaldine98.5%
CBNumber: CB8348955
Molecular Formula: C10H8ClN
Formula Weight: 177.63
MOL File: 4965-33-7.mol

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7-Chloro-2-methylquinoline Property

Melting point:: 74-78 °C (lit.)
Boiling point:: 87 °C / 0.5mmHg
Density: 1.1810 (rough estimate)
refractive index: 1.6000 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
pka: 4.25±0.50(Predicted)
form: Solid
color: Pale Yellow to Light Beige
BRN: 115318
InChI: InChI=1S/C10H8ClN/c1-7-2-3-8-4-5-9(11)6-10(8)12-7/h2-6H,1H3
InChIKey: WQZQFYRSYLXBGP-UHFFFAOYSA-N
SMILES: N1C2C(=CC=C(Cl)C=2)C=CC=1C
CAS DataBase Reference: 4965-33-7(CAS DataBase Reference)
NIST Chemistry Reference: Quinoline, 7-chloro-2-methyl-(4965-33-7)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29334900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 357669
Product name: 7-Chloroquinaldine
Purity: 99%
Packaging: 1g
Price: $64.7
Updated: 2023/01/07

TCI Chemical

Product number: C1453
Product name: 7-Chloroquinaldine
Purity: >98.0%(GC)
Packaging: 5g
Price: $26
Updated: 2025/07/31

TCI Chemical

Product number: C1453
Product name: 7-Chloroquinaldine
Purity: >98.0%(GC)
Packaging: 25g
Price: $72
Updated: 2025/07/31

TRC

Product number: C381200
Product name: 7-Chloroquinaldine
Packaging: 1g
Price: $65
Updated: 2021/12/16

AK Scientific

Product number: J93995
Product name: 7-Chloroquinaldine
Packaging: 5g
Price: $10
Updated: 2021/12/16

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7-Chloro-2-methylquinoline Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

7-Chloroquinaldine is used as the starting material in the synthesis of (E)-1-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-2-propen-1-ol (C381415); an intermediate in the synthesis of the antiasthmatic, Montelukast Sodium Salt (M568000).

Synthesis

109-92-2

108-42-9

4965-33-7

To a 50 mL round-bottomed flask equipped with a condenser and a PTFE stirrer was added m-chloroaniline (1 mmol), acetonitrile (5 mL), Catalyst 1 (10 mol%), and vinyl ether (3 mmol). The reaction mixture was heated in air at 80 °C for the reaction time referred to Table 1. The progress of the reaction was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the solvent was removed by distillation under reduced pressure and the residue was purified by silica gel column chromatography (eluent: hexane/ethyl acetate) to afford 7-chloro-2-methylquinoline. The structure of the product was confirmed by comparing the spectral data reported in the literature.

References

[1] Tetrahedron Letters, 2014, vol. 55, # 15, p. 2406 - 2409

7-Chloro-2-methylquinoline Preparation Products And Raw materials

Raw materials

Preparation Products

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7-Chloro-2-methylquinoline Suppliers

Americas 1 China 303 Europe 4 Germany 2 India 58 Japan 3 Slovakia 1 South Korea 1 Switzerland 1 Ukraine 3 United Kingdom 18 United States 41 Global 436

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View Lastest Price from 7-Chloro-2-methylquinoline manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd

Product: 7-Chloro-2-methylquinoline 4965-33-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: Customise
Release date: 2025-11-19

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 7-Chloro-2-methylquinoline 4965-33-7
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 5000kg/month
Release date: 2022-01-07

Hebei Chuanghai Biotechnology Co., Ltd

Product: 7-Chloro-2-methylquinoline 4965-33-7
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-25

4965-33-7, 7-Chloro-2-methylquinolineRelated Search:

7-CHLOROQUINOLINE METHYL THIOPHENE-2-CARBOXYLATE Methyl acetate Hydroxychloroquine sulfate Kresoxim-methyl Chloroquine sulfate Chloroquine diphosphate 5,7-Dichloro-8-hydroxyquinaldine CHLOROQUINE Hydroxychloroquine Methylparaben Bensulfuron methyl Methyl acrylate Thiophanate-methyl Methyl Parathion-methyl Difluorochloromethane 7-CHLORO-4-HYDROXY-2-(TRIFLUOROMETHYL)QUINOLINE

7ChloroQuinaldineMontelukast

7-CHLOROQUINALDINE 99%

7-Chloroquinaldine ,99%

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7-Chloroquinaldine, 7-Chloro-2-methyl-1-azanaphthalene

2-Methyl-7-chloroquinline

7-Chloro-2-methylquinoline 2-Methyl-7-chloroquinoline

Chloroquinaldine

Chloroquinaldine,98%

Montelukast7-ChloroQuinaldine

7-ChloroQuinaldine98.5%

Quinoline, 7-chloro-2-methyl-

7-Chloroquildine, 99%

7-CHLOROQUINALDINE

7-CHLORO-2-METHYLQUINOLINE

2-METHYL-7-CHLOROQUINOLINE

7-Chloroquinaldine&gt

7-Chloro-2-methylquinoline ISO 9001：2015 REACH

-Chloro-2-methylquinoline

7-chloroquine pyridine

4965-33-7

C10ClH8N

C10H8ClN

Haloquinolines

Alkylquinolines

Quinolines

Building Blocks

Quinaldines

Halogenated Heterocycles

Heterocyclic Building Blocks

Alkylquinolines

Haloquinolines

Quinolines

Quinolines, Isoquinolines & Quinoxalines

Quinolines, Quinazolines and derivatives

Halides

Quinolines, Isoquinolines & Quinoxalines

Quinoline&Isoquinoline

API

4965-33-7