N-CBZ-4-PIPERIDINEPROPIONIC ACID
- Product Name
- N-CBZ-4-PIPERIDINEPROPIONIC ACID
- CAS No.
- 63845-33-0
- Chemical Name
- N-CBZ-4-PIPERIDINEPROPIONIC ACID
- Synonyms
- 3-(1-((Benzyloxy);1-Cbz-4-Piperidinepropionic Acid;N-CBZ-4-PIPERIDINEPROPIONIC ACID;3-(1-Cbz-4-piperidyl)propanoic Acid;3-(1-(benzyloxycarbonyl)piperidin-4-yl)propanoic acid;3-(1-phenylmethoxycarbonyl-4-piperidinyl)propanoic acid;4-Piperidinepropanoic acid, 1-[(phenylmethoxy)carbonyl]-;4-(2-CARBOXY-ETHYL)-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER
- CBNumber
- CB8353599
- Molecular Formula
- C16H21NO4
- Formula Weight
- 291.34
- MOL File
- 63845-33-0.mol
N-CBZ-4-PIPERIDINEPROPIONIC ACID Property
- Boiling point:
- 469.9±28.0 °C(Predicted)
- Density
- 1.191±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 4.73±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- FC152877
- Product name
- N-Cbz-4-piperidinepropionicacid
- Packaging
- 10mg
- Price
- $203
- Updated
- 2021/12/16
- Product number
- 9778AB
- Product name
- 3-(1-((Benzyloxy)carbonyl)piperidin-4-yl)propanoicacid
- Packaging
- 1g
- Price
- $239
- Updated
- 2021/12/16
- Product number
- FC152877
- Product name
- N-Cbz-4-piperidinepropionicacid
- Packaging
- 25mg
- Price
- $405
- Updated
- 2021/12/16
- Product number
- FC152877
- Product name
- N-Cbz-4-piperidinepropionicacid
- Packaging
- 2mg
- Price
- $59
- Updated
- 2021/12/16
- Product number
- FC152877
- Product name
- N-Cbz-4-piperidinepropionicacid
- Packaging
- 5mg
- Price
- $117
- Updated
- 2021/12/16
N-CBZ-4-PIPERIDINEPROPIONIC ACID Chemical Properties,Usage,Production
Synthesis
6318-43-0
501-53-1
63845-33-0
General procedure for the synthesis of 1-CBZ-4-piperidinepropionic acid from 3-(4-pyridyl)propionic acid and benzyl chloroformate: first, PIPERIDINE-HCL (6.5 g, 33.6 mmol) was dissolved in a mixed solvent of THF (300 mL) and saturated aqueous sodium bicarbonate (100 mL), and the reaction system was subsequently cooled to 0 °C. At this temperature, a solution of benzyl chloroformate (4.8 mL, 33.6 mmol) in THF (55 mL) was slowly added dropwise, and the dropwise process was controlled to be completed within 25 minutes. After the dropwise addition was completed, the reaction mixture was kept at 0 °C to continue the reaction for 6 hours. Upon completion of the reaction, the THF solvent was removed by vacuum concentration. Subsequently, the concentrated mixture was partitioned between chloroform and 3M HCl solution until gas escape ceased and the pH reached 2-3. The solid product was collected by filtration, while the filtrate was dried with anhydrous sodium sulfate and concentrated again under vacuum to give 1-(benzyloxymethyl)-4-piperidinonanoic acid (10 g, quantitative yield) as a light yellow oil.
References
[1] Patent: WO2004/58702, 2004, A2. Location in patent: Page 46; 27
N-CBZ-4-PIPERIDINEPROPIONIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
N-CBZ-4-PIPERIDINEPROPIONIC ACID Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
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View Lastest Price from N-CBZ-4-PIPERIDINEPROPIONIC ACID manufacturers
- Product
- N-CBZ-4-PIPERIDINEPROPIONIC ACID 63845-33-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-10