2-MERCAPTO-5-NITROBENZIMIDAZOLE
- Product Name
- 2-MERCAPTO-5-NITROBENZIMIDAZOLE
- CAS No.
- 6325-91-3
- Chemical Name
- 2-MERCAPTO-5-NITROBENZIMIDAZOLE
- Synonyms
- 5-Nitro-1H-benzo[d]iMidazole-2-thiol;TIMTEC-BB SBB006921;LABOTEST-BB LT00455452;Ilaprazole Impurity 84;5-NITRO-2-BENZIMIDAZOLTHIOL;5-NITRO-2-BENZIMIDAZOLETHIOL;2-MERCAPTO-5-NITROBENZIMIDAZOLE;5-NITRO-2-MERCAPTO BENZIMIDAZOLE;5-Nitro-1H-benzimidazole-2-thiol;2-Mercapto-5-nitrobenzimidazole>
- CBNumber
- CB8356459
- Molecular Formula
- C7H5N3O2S
- Formula Weight
- 195.2
- MOL File
- 6325-91-3.mol
2-MERCAPTO-5-NITROBENZIMIDAZOLE Property
- Melting point:
- 274 °C (dec.) (lit.)
- Boiling point:
- 348.4±44.0 °C(Predicted)
- Density
- 1.4666 (rough estimate)
- refractive index
- 1.6740 (estimate)
- storage temp.
- -20°C Freezer, Under inert atmosphere
- solubility
- 1 M NaOH: soluble50mg/mL, opaque, dark red
- pka
- 9.22±0.30(Predicted)
- form
- Solid
- color
- Light Yellow to Light Orange
- BRN
- 172127
- InChI
- InChI=1S/C7H5N3O2S/c11-10(12)4-1-2-5-6(3-4)9-7(13)8-5/h1-3H,(H2,8,9,13)
- InChIKey
- YPXQSGWOGQPLQO-UHFFFAOYSA-N
- SMILES
- C1(=S)NC2=CC=C([N+]([O-])=O)C=C2N1
- CAS DataBase Reference
- 6325-91-3(CAS DataBase Reference)
- EPA Substance Registry System
- 2H-Benzimidazole-2-thione, 1,3-dihydro-5-nitro- (6325-91-3)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 263575
- Product name
- 2-Mercapto-5-nitrobenzimidazole
- Purity
- 97%
- Packaging
- 5g
- Price
- $34.03
- Updated
- 2025/07/31
- Product number
- M1325
- Product name
- 2-Mercapto-5-nitrobenzimidazole
- Purity
- >98.0%(HPLC)
- Packaging
- 5g
- Price
- $136
- Updated
- 2024/03/01
- Product number
- M1325
- Product name
- 2-Mercapto-5-nitrobenzimidazole
- Purity
- >98.0%(HPLC)
- Packaging
- 25g
- Price
- $543
- Updated
- 2024/03/01
- Product number
- M220488
- Product name
- 2-Mercapto-5-nitrobenzimidazole
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR53164
- Product name
- 5-Nitro-2-sulphanyl-1H-benzimidazole
- Packaging
- 1g
- Price
- $18
- Updated
- 2021/12/16
2-MERCAPTO-5-NITROBENZIMIDAZOLE Chemical Properties,Usage,Production
Chemical Properties
yellow-brown crystalline powder
Uses
2-Mercapto-5-nitrobenzimidazole is useful for treating giardiasis. Antigiardial drug.
General Description
2-Mercapto-5-nitrobenzimidazole (MNB) is a charge transfer molecule and its influence on SiO2 and Au electrode on pentacene organic thin film transistors has been investigated. The treatment of the Au electrodes of an organic bottom-contact thin film transistor with MNB, improves the current-voltage characteristics.
Synthesis
75-15-0
99-56-9
6325-91-3
GENERAL METHOD: 4-Nitro-o-phenylenediamine (0.019 mol) and water (3 mL) were sequentially added to a mixed solution containing sodium hydroxide (0.022 mol), methanol (20 mL) and carbon disulfide (0.022 mol). The reaction mixture was heated to reflux for 3 hours. Subsequently, activated carbon was added cautiously and reflux was continued for 10 minutes before the activated carbon was removed by thermal filtration. The filtrate was heated to 60-70 °C and the reaction was quenched with water (20 mL) preheated to 70 °C, followed by the slow addition of 50% acetic acid solution (9 mL) under vigorous stirring. The reaction solution was cooled in a refrigerator for 3 h to promote crystallization, and the target product 2-mercapto-5-nitrobenzimidazole was finally isolated.
References
[1] European Journal of Medicinal Chemistry, 2013, vol. 63, p. 696 - 701
[2] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 19, p. 6317 - 6326
[3] ACS Combinatorial Science, 2017, vol. 19, # 12, p. 738 - 747
[4] Journal of the Indian Chemical Society, 1984, vol. 61, # 1, p. 89 - 91
[5] Bioorganic and Medicinal Chemistry, 2005, vol. 13, # 19, p. 5550 - 5559
2-MERCAPTO-5-NITROBENZIMIDAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-MERCAPTO-5-NITROBENZIMIDAZOLE manufacturers
- Product
- 2-MERCAPTO-5-NITROBENZIMIDAZOLE 6325-91-3
- Price
- US $35.00-1.20/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-17
- Product
- 2-MERCAPTO-5-NITROBENZIMIDAZOLE 6325-91-3
- Price
- US $2.00/kg
- Min. Order
- 1kg
- Purity
- 9%
- Supply Ability
- 100kg
- Release date
- 2018-12-23