ChemicalBook > CAS DataBase List > 2-MERCAPTO-5-NITROBENZIMIDAZOLE

2-MERCAPTO-5-NITROBENZIMIDAZOLE

Product Name: 2-MERCAPTO-5-NITROBENZIMIDAZOLE
CAS No.: 6325-91-3
Chemical Name: 2-MERCAPTO-5-NITROBENZIMIDAZOLE
Synonyms: 5-Nitro-1H-benzo[d]iMidazole-2-thiol;TIMTEC-BB SBB006921;LABOTEST-BB LT00455452;Ilaprazole Impurity 84;5-NITRO-2-BENZIMIDAZOLTHIOL;5-NITRO-2-BENZIMIDAZOLETHIOL;2-MERCAPTO-5-NITROBENZIMIDAZOLE;5-NITRO-2-MERCAPTO BENZIMIDAZOLE;5-Nitro-1H-benzimidazole-2-thiol;2-Mercapto-5-nitrobenzimidazole>
CBNumber: CB8356459
Molecular Formula: C7H5N3O2S
Formula Weight: 195.2
MOL File: 6325-91-3.mol

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2-MERCAPTO-5-NITROBENZIMIDAZOLE Property

Melting point:: 274 °C (dec.) (lit.)
Boiling point:: 348.4±44.0 °C(Predicted)
Density: 1.4666 (rough estimate)
refractive index: 1.6740 (estimate)
storage temp.: -20°C Freezer, Under inert atmosphere
solubility: 1 M NaOH: soluble50mg/mL, opaque, dark red
pka: 9.22±0.30(Predicted)
form: Solid
color: Light Yellow to Light Orange
BRN: 172127
InChI: InChI=1S/C7H5N3O2S/c11-10(12)4-1-2-5-6(3-4)9-7(13)8-5/h1-3H,(H2,8,9,13)
InChIKey: YPXQSGWOGQPLQO-UHFFFAOYSA-N
SMILES: C1(=S)NC2=CC=C([N+]([O-])=O)C=C2N1
CAS DataBase Reference: 6325-91-3(CAS DataBase Reference)
EPA Substance Registry System: 2H-Benzimidazole-2-thione, 1,3-dihydro-5-nitro- (6325-91-3)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
TSCA: Yes
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 263575
Product name: 2-Mercapto-5-nitrobenzimidazole
Purity: 97%
Packaging: 5g
Price: $34.03
Updated: 2025/07/31

TCI Chemical

Product number: M1325
Product name: 2-Mercapto-5-nitrobenzimidazole
Purity: >98.0%(HPLC)
Packaging: 5g
Price: $136
Updated: 2024/03/01

TCI Chemical

Product number: M1325
Product name: 2-Mercapto-5-nitrobenzimidazole
Purity: >98.0%(HPLC)
Packaging: 25g
Price: $543
Updated: 2024/03/01

TRC

Product number: M220488
Product name: 2-Mercapto-5-nitrobenzimidazole
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: OR53164
Product name: 5-Nitro-2-sulphanyl-1H-benzimidazole
Packaging: 1g
Price: $18
Updated: 2021/12/16

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2-MERCAPTO-5-NITROBENZIMIDAZOLE Chemical Properties,Usage,Production

Chemical Properties

yellow-brown crystalline powder

Uses

2-Mercapto-5-nitrobenzimidazole is useful for treating giardiasis. Antigiardial drug.

General Description

2-Mercapto-5-nitrobenzimidazole (MNB) is a charge transfer molecule and its influence on SiO₂ and Au electrode on pentacene organic thin film transistors has been investigated. The treatment of the Au electrodes of an organic bottom-contact thin film transistor with MNB, improves the current-voltage characteristics.

Synthesis

75-15-0

99-56-9

6325-91-3

GENERAL METHOD: 4-Nitro-o-phenylenediamine (0.019 mol) and water (3 mL) were sequentially added to a mixed solution containing sodium hydroxide (0.022 mol), methanol (20 mL) and carbon disulfide (0.022 mol). The reaction mixture was heated to reflux for 3 hours. Subsequently, activated carbon was added cautiously and reflux was continued for 10 minutes before the activated carbon was removed by thermal filtration. The filtrate was heated to 60-70 °C and the reaction was quenched with water (20 mL) preheated to 70 °C, followed by the slow addition of 50% acetic acid solution (9 mL) under vigorous stirring. The reaction solution was cooled in a refrigerator for 3 h to promote crystallization, and the target product 2-mercapto-5-nitrobenzimidazole was finally isolated.

References

[1] European Journal of Medicinal Chemistry, 2013, vol. 63, p. 696 - 701
[2] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 19, p. 6317 - 6326
[3] ACS Combinatorial Science, 2017, vol. 19, # 12, p. 738 - 747
[4] Journal of the Indian Chemical Society, 1984, vol. 61, # 1, p. 89 - 91
[5] Bioorganic and Medicinal Chemistry, 2005, vol. 13, # 19, p. 5550 - 5559

2-MERCAPTO-5-NITROBENZIMIDAZOLE Preparation Products And Raw materials

Raw materials

4-Nitro-o-phenylenediamine Potassium hydroxide Carbon disulfide Methanol Activated carbon

Preparation Products

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View Lastest Price from 2-MERCAPTO-5-NITROBENZIMIDAZOLE manufacturers

Henan Fengda Chemical Co., Ltd

Product: 2-MERCAPTO-5-NITROBENZIMIDAZOLE 6325-91-3
Price: US $35.00-1.20/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-17

Career Henan Chemical Co

Product: 2-MERCAPTO-5-NITROBENZIMIDAZOLE 6325-91-3
Price: US $2.00/kg
Min. Order: 1kg
Purity: 9%
Supply Ability: 100kg
Release date: 2018-12-23

6325-91-3, 2-MERCAPTO-5-NITROBENZIMIDAZOLERelated Search:

2-MERCAPTO-5-NITROBENZIMIDAZOLE 5-Nitrobenzimidazole 1-(2-METHOXY-PHENYL)-5-NITRO-1H-BENZOIMIDAZOLE-2-THIOL (6-NITRO-1 H-BENZOIMIDAZOL-2-YLSULFANYL)-ACETIC ACID 5-NITRO-1-PHENYL-1H-BENZIMIDAZOLE-2-THIOL ZERENEX E/5051468 2-[(2-CHLORO-4-PYRIMIDINYL)SULFANYL]-5-NITRO-1H-BENZIMIDAZOLE 2-[(6-NITRO-1H-BENZIMIDAZOL-2-YL)THIO]ACETAMIDE 2-(ISOPROPYLTHIO)-5-NITRO-1H-BENZIMIDAZOLE AKOS BBS-00001855 RARECHEM AL FL 0032 2-(METHYLTHIO)-5-NITRO-1H-BENZIMIDAZOLE 3-(5-NITRO-1H-BENZOIMIDAZOL-2-YLSULFANYL)-PROPIONIC ACID 2-(5-NITRO-1H-BENZOIMIDAZOL-2-YLSULFANYL)-PROPIONIC ACID [(5-NITRO-1-PHENYL-1H-BENZIMIDAZOL-2-YL)THIO]ACETIC ACID [(5-NITRO-1H-BENZIMIDAZOL-2-YL)THIO]ACETIC ACID 2-(5-NITRO-1H-BENZOIMIDAZOL-2-YLSULFANYL)-ACETAMIDE 5-NITRO-1-[3-(TRIFLUOROMETHYL)PHENYL]-1H-BENZIMIDAZOLE-2-THIOL

LABOTEST-BB LT00455452

2-MERCAPTO-5-NITROBENZIMIDAZOLE

TIMTEC-BB SBB006921

5-NITRO-2-BENZIMIDAZOLTHIOL

5-NITRO-2-MERCAPTO BENZIMIDAZOLE

5-NITRO-2-BENZIMIDAZOLETHIOL

2-MERCAPTO-5-NITROBENZIMIDAZOLE APPROX. 97%

2H-Benzimidazole-2-thione,1,3-dihydro-5-nitro-(9CI)

5-nitro-1H-benzo[d]iMidazole-2(3H)-thione

5-nitro-1H-1,3-benzodiazole-2-thiol

5-Nitro-1H-benzo[d]iMidazole-2-thiol

2-Mercapto-5-nitrobenzimidazole 97%

2H-Benzimidazole-2-thione, 1,3-dihydro-5-nitro-

5-nitro-1,3-dihydrobenzoimidazole-2-thione

2-Mercapto-5-nitro-1H-benzimidazole

5-Nitro-1,3-dihydro-2H-benzimidazole-2-thione

5-Nitro-1H-benzimidazole-2(3H)-thione

5-Nitro-1H-benzimidazole-2-thiol

6-Nitro-2-mercapto-1H-benzimidazole

2-Mercapto-5-nitrobenzimidazole,97%

5-Nitro-2-sulphanyl-1H-benzimidazole

5-Nitro-2-sulfanyl-1H-benzimidazole

5-nitro-1,7a-dihydrobenzimidazole-2-thione

2-Mercapto-5-nitrobenzimidazole&gt

1,3-Dihydro-5-Nitro-2H-Benzimidazole-2-Thione

2-MERCAPTO-5-NITROBENZIMIDAZOLEAPPROX.97%

5-NITRO-2-MERCAPTOBENZIMIDChemicalbookAZOLE

Ilaprazole Impurity 84

6325-91-3

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