NS 1619
- Product Name
- NS 1619
- CAS No.
- 153587-01-0
- Chemical Name
- NS 1619
- Synonyms
- NS 161;NS 1619;NS1619;NS 1619;NS 1619 (1,3-DIHYDRO-1-(2-HYDROXY-5-(TRI FLUOROMETHYL)PHEN;1-(2-hydroxy-5-(trifluoroMethyl)phenyl)-5-(trifluoroMethyl)-1H-b;1-(2-Hydroxy-5-(Trifluoromethyl)Phenyl)-5-(Trifluoromethyl)-1H-Benzo[D]Imidazol-2-Ol;1-(2-hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one;1,3-DIHYDRO-1-[2-HYDROXY-5-(TRIFLUOROMETHYL)PHENYL]-5-(TRIFLUOROMETHYL)-2H-BENZIMIDAZOL-2-ONE;1-[2-Hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-1,3-dihydro-2H-benzimidazol-2-one;2H-Benzimidazol-2-one, 1,3-dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-
- CBNumber
- CB8359809
- Molecular Formula
- C15H8F6N2O2
- Formula Weight
- 362.23
- MOL File
- 153587-01-0.mol
NS 1619 Property
- Density
- 1.563±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.47 mg/mL
- pka
- 8.32±0.48(Predicted)
- form
- solid
- color
- white
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- N170
- Product name
- NS 1619
- Purity
- powder
- Packaging
- 5mg
- Price
- $180
- Updated
- 2024/03/01
- Product number
- N170
- Product name
- NS 1619
- Purity
- powder
- Packaging
- 25mg
- Price
- $645
- Updated
- 2024/03/01
- Product number
- 18876
- Product name
- NS 1619
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $37
- Updated
- 2024/03/01
- Product number
- 18876
- Product name
- NS 1619
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $81
- Updated
- 2024/03/01
- Product number
- 18876
- Product name
- NS 1619
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $142
- Updated
- 2024/03/01
NS 1619 Chemical Properties,Usage,Production
Uses
NS 1619 is a large conductance calcium-activated potassium channels (BKCa) activator and has been shown to induce precondition in the heart.
Definition
ChEBI: A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It i an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).
Biochem/physiol Actions
NS 1619 is a selective large conductance Ca2+-activated K+-channel activator. The compound is known for its vasodilating and anti-proliferative properties. It is studied that NS 1619 can protect cardiac muscle against ischemia and reperfusion injury.
storage
+4°C
NS 1619 Preparation Products And Raw materials
Raw materials
Preparation Products
NS 1619 Suppliers
- Tel
- --
- Fax
- --
- Country
- Switzerland
- ProdList
- 6896
- Advantage
- 91
View Lastest Price from NS 1619 manufacturers
- Product
- NS 1619 153587-01-0
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-13